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What is an Antibody Library?

Antibody libraries are increasingly being used by researchers to find new drug targets, antibodies, biomarkers of disease, and so forth.

13 May 2021

Computational Modeling in Medicine

Computational modeling has provided ever-more sophisticated data for the field of medical research and medicine.

12 May 2021

What is an Epitope?

An epitope is the part of an antigen that the host’s immune system recognizes, eliciting the immune response to an invading pathogen.

10 May 2021

What is Exon Skipping?

Exon skipping has shown promise as a therapy for inherited conditions such as Duchenne muscular dystrophy.

7 May 2021

What is SiRNA?

siRNAs are currently being evaluated as to how they can be exploited in the drug development process and as therapeutic agents.

4 May 2021

What is Preclinical Immunogenicity Assessment?

Assessing the immunogenicity of any drug or therapeutic is essential to assessing efficacy and toxicity at the early stages of drug discovery.

3 May 2021

The Future of Precision Medicine

Precision medicine aims to create specialized treatment regimens that are tailored to each individual’s unique genetics, environment, and lifestyle.

26 Apr 2021

The Development of DNA Vaccines

DNA vaccines have been widely studied for their ability to induce both cellular and humoral immune responses against certain infectious agents.

22 Apr 2021

Nanotechnology: The Answer to Opioid Therapy?

An international research group has focused on using nanoparticle use to transport non-opioid drugs into nerves for pain relief.

20 Apr 2021

Nanobowls in Medicine

Nanobowls represent a cutting-edge solution for the medical sciences and research is ongoing into their continued use for the field.

19 Apr 2021

Computational Modeling in Developmental Biology

Computational modeling is increasingly used to improve understanding of complex systems such as those in developmental biology.

14 Apr 2021

What are Morpholinos?

A morpholino is a synthetic oligomer molecule that contains DNA bases on a methylene morpholine backbone. The name comes from morpholine oligomer.

12 Apr 2021

Testing for Hormone-like Effects of Chemicals

Many chemicals are structurally similar to endogenous hormones and can disrupt the normal functioning of the endocrine system.

24 Mar 2021

What is the Global Preclinical Antibacterial Pipeline?

Antibacterial resistance requires prompt global action to ensure that new antibacterial drugs are continuously developed against mutating strains of bacteria.

23 Mar 2021

The Thermal Inactivation of SARS-CoV-2

Viruses like SARS-CoV-2 are sensitive to thermal inactivation - temperature extremes that denature their constituent proteins and disable their function.

22 Mar 2021

Human Tumor Xenograft Models

In human tumor xenograft models, human tumor cells are transplanted into immunocompromised mice that do not reject human cells.

19 Mar 2021

What is Quantitative Systems Pharmacology (QSP) Modeling?

Quantitative systems pharmacology (QSP) is a field of biomedical research that aims to model the mechanisms behind disease progression.

18 Mar 2021

What are RNA Therapeutics?

RNA therapeutics utilize exogenously delivered RNA to instruct for the production of proteins, disrupt the production of proteins, or act as a targeting ligand.

17 Mar 2021

Primary vs Secondary Assays in Preclinical Testing

During the preclinical testing phase of drug discovery, compounds go through primary and secondary assays to determine potential for treatment of a disease.

12 Mar 2021