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What are Anti-PEG Antibodies and Why are they Useful?

PEG, or polyethylene glycol, is a synthetically constructed polymer, made of repeating units of ethylene glycol (-CH2-CH2-O-).

30 Jan 2020

What are Biotinylated Antibodies?

The term biotinylation refers to the process of binding biotin to either a protein or a nucleic acid, or in some cases to another type of molecule.

30 Jan 2020

An Overview of Red Blood Cell Lysis

Red blood cell lysis is more commonly known as hemolysis, or sometimes haemolysis

30 Jan 2020

What is Tumorigenesis?

A tumor is an abnormal growth of cells, usually facilitated by a lack of apoptosis, therefore allowing for uncontrolled growth of unwanted or damaged cells.

30 Jan 2020

How Can Animal Cell Lines Reduce Lab Animal Use?

The use of animals in research came about as scientists tried to understand the disease process and find ways of treating or curing diseases.

30 Jan 2020

Recent Progress of In Vitro Toxicity Assays in Drug Discovery

Investigating the potential toxicity of any new drug is vital for its progress into the marketplace.

30 Jan 2020

Validating the In-Silico Model for Toxicity Studies

Any experimental model or simulation must adhere to a series of validity requirements that confirm its applicability and reliability.

30 Jan 2020

$What Role does X-Ray Diffraction have in Drug Analysis?$

What Role does X-Ray Diffraction have in Drug Analysis?

X-ray techniques have been used for decades by authorities to prevent crime and keep people safe. Perhaps their most well-known use is for the detection of dangerous and banned items or substances.

20 Jan 2020

What is Time-Resolved Fluorescence Spectroscopy?

Time-resolved fluorescence spectroscopy is a spectroscopy technique used to monitor interactions between molecules and motions that occur in the short periods. The ability to measure changes in the picosecond or nanosecond time range makes it a useful technique in biomolecular structure analysis and dynamics.

17 Jan 2020

What is Point Accumulation for Imaging in Nanoscale Topography (PAINT)?

Biological systems are incredibly complex, with numerous types of cells working together in tissues and organs, performing processes necessary to sustain life. To fully understand these processes and their implications a variety of techniques have been developed and refined over the years.

17 Jan 2020

What is Fluorescence Force Microscopy?

Fluorescence force microscopy is a combination of atomic force microscopy and fluorescence microscopy, which allows molecular dynamics to be studied. The technique can be applied to single molecules, allowing a more in-depth study of protein folding, for example in cellular dynamics and cell movement.

17 Jan 2020

What are Stereo Microscopes Used For?

Conventional light microscopy is a widely used tool in several areas of scientific study. Light microscopes typically come in two main variants: The compound microscope and the stereo microscope, which both have their uses, although stereo microscopes have distinct advantages over compound microscopes when it comes to studying certain types of sample.

17 Jan 2020

Portable Microscopes: Advantages and Disadvantages

Portable optical light microscopes are widely used tools in the field of microscopy. Found in laboratories both large and small, as well as schools and colleges, they are a simple and elegant solution that helps scientists peer into the microscopic world and reveal structures invisible to the naked eye.

17 Jan 2020

How to Measure Intracellular Oxygen Levels in Live Cells

Oxygen is an essential molecule for anaerobic organisms, acting as a terminal electron acceptor in the process of cellular energy generation. It is also used as a substrate in several enzymatic reactions. Oxygen homeostasis is important for the healthy maintenance of the entire organism.

17 Jan 2020

Disease Susceptibility and the Microbiome

Over the past decade, there has been a growing body of research that has sought to understand the complex role the microbiome plays in disease regulation. The results of these studies have brought us closer to understanding these processes and have thrown light on the complexity of the immune system.

17 Jan 2020

Bright field Versus Dark-field TEM

Transmission electron microscopy (TEM) is a common technique for studying nanomolecular structures that cannot be resolved using traditional light microscopy. Compared with SEM (scanning electron microscopy) TEM provides images of cross-sections of a target subject and is suited to the study of objects such as organic tissue and crystalline lattices.

17 Jan 2020