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A Comparison of Immunohistochemistry and Western Blot

Immunohistochemistry and Western blotting both work by exploiting the principle of how antibodies specifically bind to the antigens present in biological tissue.

3 Feb 2020

An Overview of the Cholesterol Biosynthesis Pathway

Cholesterol is a multi-functional lipid that has been studied heavily for many years.

3 Feb 2020

A Guide to Fluorescence

The phenomenon of fluorescence is a form of luminescence, exploited by techniques that have innovated ways to utilize its light emittance.

3 Feb 2020

What are Biological Phosphors?

Phosphors refer to a group of solid materials that emit visible light, or luminesces, in response to exposure to radiation in the form of ultraviolet light or an electron beam.

3 Feb 2020

Improving Patient Outcomes in Positive Crossmatch Kidney Transplantation

A team has conducted a study to demonstrate that patients undergone desensitization show improved survival.

31 Jan 2020

A Novel FACS-based Approach to Isoagglutinin Concentration in Products for Intravenous Use

A research group, have published a paper in which they describe a fluorescence-activated cell sorting (FACS)-based method for isoagglutinin quantification.

31 Jan 2020

Flow Cytometry May Improve Transplant Outcomes

A team of researchers have established a technique for helping to improve transplant outcomes for patients with diabetes undergoing islet transplantation.

31 Jan 2020

What are Neuroepithelial Cells?

Neuroepithelial cells are stem cells that differentiate into neurons and glia, following the process of neurogenesis.

30 Jan 2020

What are Anti-PEG Antibodies and Why are they Useful?

PEG, or polyethylene glycol, is a synthetically constructed polymer, made of repeating units of ethylene glycol (-CH2-CH2-O-).

30 Jan 2020

What are Biotinylated Antibodies?

The term biotinylation refers to the process of binding biotin to either a protein or a nucleic acid, or in some cases to another type of molecule.

30 Jan 2020

An Overview of Red Blood Cell Lysis

Red blood cell lysis is more commonly known as hemolysis, or sometimes haemolysis

30 Jan 2020

What is Tumorigenesis?

A tumor is an abnormal growth of cells, usually facilitated by a lack of apoptosis, therefore allowing for uncontrolled growth of unwanted or damaged cells.

30 Jan 2020

How Can Animal Cell Lines Reduce Lab Animal Use?

The use of animals in research came about as scientists tried to understand the disease process and find ways of treating or curing diseases.

30 Jan 2020

Recent Progress of In Vitro Toxicity Assays in Drug Discovery

Investigating the potential toxicity of any new drug is vital for its progress into the marketplace.

30 Jan 2020

Validating the In-Silico Model for Toxicity Studies

Any experimental model or simulation must adhere to a series of validity requirements that confirm its applicability and reliability.

30 Jan 2020

$What Role does X-Ray Diffraction have in Drug Analysis?$

What Role does X-Ray Diffraction have in Drug Analysis?

X-ray techniques have been used for decades by authorities to prevent crime and keep people safe. Perhaps their most well-known use is for the detection of dangerous and banned items or substances.

20 Jan 2020

What is Time-Resolved Fluorescence Spectroscopy?

Time-resolved fluorescence spectroscopy is a spectroscopy technique used to monitor interactions between molecules and motions that occur in the short periods. The ability to measure changes in the picosecond or nanosecond time range makes it a useful technique in biomolecular structure analysis and dynamics.

17 Jan 2020

What is Point Accumulation for Imaging in Nanoscale Topography (PAINT)?

Biological systems are incredibly complex, with numerous types of cells working together in tissues and organs, performing processes necessary to sustain life. To fully understand these processes and their implications a variety of techniques have been developed and refined over the years.

17 Jan 2020

What is Fluorescence Force Microscopy?

Fluorescence force microscopy is a combination of atomic force microscopy and fluorescence microscopy, which allows molecular dynamics to be studied. The technique can be applied to single molecules, allowing a more in-depth study of protein folding, for example in cellular dynamics and cell movement.

17 Jan 2020

What are Stereo Microscopes Used For?

Conventional light microscopy is a widely used tool in several areas of scientific study. Light microscopes typically come in two main variants: The compound microscope and the stereo microscope, which both have their uses, although stereo microscopes have distinct advantages over compound microscopes when it comes to studying certain types of sample.

17 Jan 2020