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Studies shed light on the versatility, precision, and sensitivity of quantitative analytical tools

Three independent studies in the Journal of Pharmaceutical Analysis explore the potential uses and applications of quantitative analytical tools in the characterization and quality assessment of biological and medicinal compounds.

19 Aug 2021

Arteriolar niche used by breast cancer cells to prepare for metastasis

More than 43,000 American women will die from breast cancer this year. Most of those deaths will occur after the cancer has spread to other organs, a process called metastasis. This involves at least five major steps.

19 Aug 2021

Memory of specific events does not deteriorate with age in cuttlefish

Cuttlefish can remember what, where, and when specific events happened - right up to their last few days of life, researchers have found.

18 Aug 2021

Auditory and speech processing occur in parallel in the brain

After years of research, neuroscientists have discovered a new pathway in the human brain that processes the sounds of language.

18 Aug 2021

Remote controlling of CAR-T cells with heat to precisely target tumors

A team of researchers led by bioengineers at the Georgia Institute of Technology is expanding the precision and ability of a revolutionary immunotherapy that is already transforming oncology. CAR T-Cell therapy has been hailed by patients, clinical-researchers, investors, and the media as a viable cure for some cancers.

18 Aug 2021

Videos capture the inexorable spread of SARS-CoV-2 in live animals

Video images capture for the first time in live animals the inexorable spread of the COVID-19 virus, tracking the infection as it moved from the noses of mice to the lungs and other organs over the course of six days, in a new study led by researchers at Yale and Université de Montréal.

18 Aug 2021

Study shows how mesenchymal stromal cells regulate factors driving inflammation in COPD patients

A new phase I clinical study shows, for the first time, how treatment with a type of stem cell called mesenchymal stromal cells is able to regulate important factors driving inflammation in patients with chronic obstructive pulmonary disease (COPD) for a period for time.

18 Aug 2021

CRISPR screening tool pinpoints new therapeutic target to treat acute myeloid leukemia

A CRISPR screening tool identified a new therapeutic target to treat acute myeloid leukemia (AML) that has the potential to leave patients with fewer side effects than current approaches, according to a new study from Penn Medicine published online in Molecular Cell.

18 Aug 2021

Scientists propose innovative method to test the effectiveness of coronavirus medicines

South Ural State University scientists have proposed an innovative method for testing the effectiveness of medicines for coronavirus. According to the researchers, it is necessary to focus on the maximum coincidence of the ligand and the receptor. The results of the work have been published in the highly-rated journal "Molecules"(Q1).

18 Aug 2021

New assay using fresh uncultured lung tumor cells could guide personalized treatments

A new study from the University of Helsinki shows that cells that are freshly isolated from lung cancers can be used to create robust drug response data. This approach can identify actionable or non-responsive treatments, illustrated by a case study in which the assay was used to guide the compassionate treatment of a patient.

18 Aug 2021

ELRIG UK Announces Drug Discovery 2021 Event to Host SLAS’s Innovation AveNEW

The European Laboratory Research & Innovation Group today announced the programme details for Drug Discovery 2021.

From Society for Laboratory Automation and Screening (SLAS) 18 Aug 2021

Promega's complete workflow quickly provides a snapshot of community-wide infection rates using wastewater samples

A complete workflow developed by Promega Corporation enables wastewater testing laboratories, including public health organizations, to quickly assess the health of entire communities from a single sample.

18 Aug 2021

Fundamental theory on how metabolism affects population demography needs revision, research suggests

All organisms must eat to sustain themselves, but some more so than others.

18 Aug 2021

Designing antimalarials with multiple targeting mechanisms of action

Malaria remains a serious global health threat. While the current discoveries of antimalarials are almost totally focused on single mode-of-action inhibitors, multi-targeting inhibitors are highly desired to overcome the increasingly serious drug resistance.

18 Aug 2021

SpeeDx expands product line of research reagents for SARS-CoV-2 variant analysis

SpeeDx Pty. Ltd., a developer of innovative molecular diagnostic solutions, have expanded their product line of research reagents for COVID-19 variant analysis to include a mutation connected to the SARS-CoV-2 Delta variant of concern.

18 Aug 2021

New bioengineered lung model could help scientists to advance research in lung conditions

An interdisciplinary team of researchers from McMaster and SickKids are developing a cutting-edge lung model that can better respond to viruses and drug treatments, giving scientists a tool to advance research in lung conditions like COVID-19, cystic fibrosis and allergens for asthma and air pollution.

18 Aug 2021

Simple model captures the key mechanics of hand-washing

Though hand-washing is proven effective in combating the spread of disease and infection, the physics behind it has rarely been studied. But in Physics of Fluids, by AIP Publishing, researchers from Hammond Consulting Limited describe a simple model that captures the key mechanics of hand-washing.

17 Aug 2021

Scientists could elucidate how and why gut microbes contribute to cognitive impairment

Recent research has found that changes in the gut microbiota - the trillions of bacteria and other microbes that live in the intestines - can alter the brain and behavior. Now, a study led by scientists at UCLA could elucidate how and why that phenomenon occurs.

17 Aug 2021

Age and sex affect the outcomes of time-restricted eating

Time-restricted eating (TRE), a dietary regimen that restricts eating to specific hours, has garnered increased attention in weight-loss circles.

17 Aug 2021

Researchers report potential of a berry-producing vine against lung cancer in mice

Lung cancer is known to be the most fatal form of cancer. Chemicals like 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) found in tobacco are usually the main culprits behind smoking-related lung cancer causing cancer biologists to actively explore targeted treatments.

17 Aug 2021

Life Science News

Studies shed light on the versatility, precision, and sensitivity of quantitative analytical tools

Arteriolar niche used by breast cancer cells to prepare for metastasis

Memory of specific events does not deteriorate with age in cuttlefish

Auditory and speech processing occur in parallel in the brain

Remote controlling of CAR-T cells with heat to precisely target tumors

Videos capture the inexorable spread of SARS-CoV-2 in live animals

Study shows how mesenchymal stromal cells regulate factors driving inflammation in COPD patients

CRISPR screening tool pinpoints new therapeutic target to treat acute myeloid leukemia

Scientists propose innovative method to test the effectiveness of coronavirus medicines

New assay using fresh uncultured lung tumor cells could guide personalized treatments

ELRIG UK Announces Drug Discovery 2021 Event to Host SLAS’s Innovation AveNEW

Promega's complete workflow quickly provides a snapshot of community-wide infection rates using wastewater samples

Fundamental theory on how metabolism affects population demography needs revision, research suggests

Designing antimalarials with multiple targeting mechanisms of action

SpeeDx expands product line of research reagents for SARS-CoV-2 variant analysis

New bioengineered lung model could help scientists to advance research in lung conditions

Simple model captures the key mechanics of hand-washing

Scientists could elucidate how and why gut microbes contribute to cognitive impairment

Age and sex affect the outcomes of time-restricted eating

Researchers report potential of a berry-producing vine against lung cancer in mice

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

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