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Novel approach to gene editing bypasses disease-causing mutations in a gene

A new approach to gene editing using the CRISPR/Cas9 system bypasses disease-causing mutations in a gene, enabling treatment of genetic diseases linked to a single gene, such as cystic fibrosis, certain types of sickle cell anemia, and other rare diseases.

21 Apr 2021

Argonne's Advanced Photon Source guided the development of new COVID-19 vaccine now in trials

Human clinical trials have begun on a new vaccine candidate that may protect against not only SARS-CoV-2, the virus that causes COVID-19, but against at least two of the variants emerging around the world.

21 Apr 2021

SARS-CoV-2 infection induces polyfunctional antibodies that can destroy infected cells

Drawing on epidemiological field studies and the FrenchCOVID hospital cohort coordinated by Inserm, teams from the Institut Pasteur, the CNRS and the Vaccine Research Institute (VRI, Inserm/University Paris-Est Créteil) studied the antibodies induced in individuals with asymptomatic or symptomatic SARS-CoV-2 infection.

21 Apr 2021

Researchers discover how SARS viruses enhance the production of viral proteins in infected cells

Coronavirus researchers led by Professor Rolf Hilgenfeld of the University of Luebeck and PD Dr. Albrecht von Brunn of the Ludwig-Maximilian Universitaet in Munich have discovered how SARS viruses enhance the production of viral proteins in infected cells, so that many new copies of the virus can be generated.

21 Apr 2021

Study focuses on understanding the origin of neuronal diversity

A mechanistic understanding of brain development requires a systematic survey of neural progenitor cell types, their lineage specification and maturation of postmitotic neurons.

21 Apr 2021

New review examines the latest data on kiwi genetics for wildlife conservation

Kiwi are iconic birds that have been severely impacted by deforestation and predation from invasive mammals since the arrival of humans in New Zealand.

21 Apr 2021

Researchers identify the cause of severe canine juvenile epilepsy

In a study conducted at the University of Helsinki, researchers found a cause for severe epilepsy resulting in death in Parson Russell Terrier puppies at a few months of age. A change in the PITRM1 gene can lead to a dysfunction of mitochondria, the cellular energy pumps.

21 Apr 2021

Organ tissues become increasingly immune throughout life, new study suggests

University of Minnesota Medical School researchers have offered new ways to think about the immune system thanks to a recent study published in Nature.

20 Apr 2021

Asymmetric technique to synthesize aziridines in the presence of newly developed catalysts

Unless you've studied chemistry in college, it's unlikely you've come across the name aziridine. An organic compound with the molecular formula, C2H4NH, aziridines are well-known among medicinal chemists, who make use of the compound to prepare pharmaceutical drugs such as Mitomycin C, a chemotherapeutic agent known for its anti-tumor activity.

20 Apr 2021

Study challenges the assumption that all South African Bantu speakers are a single genetic entity

Almost 80% of South Africans speak one of the SEB family languages as their first language. Their origins can be traced to farmers of West-Central Africa whose descendants over the past two millennia spread south of the equator and finally into Southern Africa.

20 Apr 2021

Rare compound found in a shrub could help fight previously 'undruggable' cancer protein

A chemist from Purdue University has found a way to synthesize a compound to fight a previously "undruggable" cancer protein with benefits across a myriad of cancer types.

20 Apr 2021

New type of placental structure discovered in animals

The Cyclostomata is an ancient group of aquatic colonial suspension-feeders from the phylum Bryozoa. The fact that they have unique placentae has been discovered by researchers at St Petersburg University and the University of Vienna.

20 Apr 2021

Study evaluates stem cells' ability to prevent major cause of death in preterm infants

A phase 2 clinical trial whose results were released today in STEM CELLS Translational Medicine might point to a way to overcome bronchopulmonary dysplasia (BPD), a major cause of death in preterm infants.

20 Apr 2021

Probiotic L. acidophilus can effectively treat intestinal inflammation, research shows

Intestinal epithelial tight junctions (TJs) act as a functional and structural barrier against harmful antigens that promote intestinal inflammation in inflammatory bowel disease (IBD) and other inflammatory conditions of the gut.

20 Apr 2021

Comprehensive roadmap of muscle aging reveals potential targets for treatments

Scientists have produced a comprehensive roadmap of muscle aging in mice that could be used to find treatments that prevent decline in muscle mobility and function, according to a report published today in eLife.

20 Apr 2021

Overgrowth of gut yeast in newborns associated with increased risk of asthma

An overgrowth of yeast in the gut within the first few months of life may cause changes to the immune system that increase the risk of asthma later on, shows a study published today in eLife.

20 Apr 2021

Researchers develop new mathematical model to predict the onset of diseases

A myriad of genetic factors can influence the onset of diseases like high blood pressure, heart diseases, and type 2 diabetes.

20 Apr 2021

New algorithm uses online learning to speed up analysis of massive cell data sets

The fact that the human body is made up of cells is a basic, well-understood concept. Yet amazingly, scientists are still trying to determine the various types of cells that make up our organs and contribute to our health.

19 Apr 2021

Scientists identify protein that operates closely with a genetic mutation to spur lung cancer growth

Scientists at VCU Massey Cancer Center have identified a protein that operates in tandem with a specific genetic mutation to spur lung cancer growth and could serve as a therapeutic target to treat the disease.

19 Apr 2021

Study reveals why intellectual disability risk for younger siblings is low

Intellectual disability is most often caused by changes to the genome that take place in early fetal development and are not found in the parents’ DNA.

19 Apr 2021

Life Science News

Novel approach to gene editing bypasses disease-causing mutations in a gene

Argonne's Advanced Photon Source guided the development of new COVID-19 vaccine now in trials

SARS-CoV-2 infection induces polyfunctional antibodies that can destroy infected cells

Researchers discover how SARS viruses enhance the production of viral proteins in infected cells

Study focuses on understanding the origin of neuronal diversity

New review examines the latest data on kiwi genetics for wildlife conservation

Researchers identify the cause of severe canine juvenile epilepsy

Organ tissues become increasingly immune throughout life, new study suggests

Asymmetric technique to synthesize aziridines in the presence of newly developed catalysts

Study challenges the assumption that all South African Bantu speakers are a single genetic entity

Rare compound found in a shrub could help fight previously 'undruggable' cancer protein

New type of placental structure discovered in animals

Study evaluates stem cells' ability to prevent major cause of death in preterm infants

Probiotic L. acidophilus can effectively treat intestinal inflammation, research shows

Comprehensive roadmap of muscle aging reveals potential targets for treatments

Overgrowth of gut yeast in newborns associated with increased risk of asthma

Researchers develop new mathematical model to predict the onset of diseases

New algorithm uses online learning to speed up analysis of massive cell data sets

Scientists identify protein that operates closely with a genetic mutation to spur lung cancer growth

Study reveals why intellectual disability risk for younger siblings is low

How does norepinephrine influence anxiety-related behaviours?

Transforming Lab Workflows with Cell Culture Automation

Building Bridges to Scalable Allogeneic Cell Therapy

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