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New compound could alleviate neurological symptoms of CHARGE syndrome

CHARGE syndrome is a rare genetic disorder affecting about 1 in 10,000 newborns. It can lead to neurological and behavioural disorders for which no treatment is currently available.

28 Apr 2021

First-of-its-kind method cryopreserves fruit fly embryos in liquid nitrogen

Cryopreservation, or the long-term storage of biomaterials at ultralow temperatures, has been used across cell types and species.

28 Apr 2021

Scientists identify blood cells most likely to be targeted by HIV during a real-life infection

In the 40-some years since the beginning of the HIV/AIDS epidemic, scientists have learned a lot about the virus, the disease, and ways to treat it. But one thing they still don't completely understand is which exact cells are most susceptible to HIV infection.

28 Apr 2021

New technique to hyperpolarize and purify fumarate for MRI

A promising new concept published by an interdisciplinary research team in "Proceedings of the National Academy of Sciences" (PNAS) paves the way for major advances in the field of magnetic resonance imaging (MRI). Their new technique could significantly simplify hyperpolarized MRI, which developed around 20 years ago for observing metabolic processes in the body.

28 Apr 2021

Researchers suggest new approach to build a 'nanopore' biosensor for detecting specific molecules

Researchers have spent more than three decades developing and studying miniature biosensors that can identify single molecules. In five to 10 years, when such devices may become a staple in doctors' offices, they could detect molecular markers for cancer and other diseases and assess the effectiveness of drug treatment to fight those illnesses.

28 Apr 2021

Novel platform has potential to detect many disease-related biomarkers in just one test

Most conventional molecular diagnostics usually detect only a single disease-related biomarker. Great examples are the PCR tests currently used to diagnose COVID-19 by detecting a specific sequence from SARS-CoV-2.

28 Apr 2021

Study reveals the role of lncRNAs in immune dysfunction during severe COVID-19

Scientific studies rarely focus on long non-coding RNA molecules (lncRNAs), even though they potentially regulate several diseases. The role of several lncRNAs in anti-viral inflammatory response regulation has recently been reported.

28 Apr 2021

Scientists gain atomic-level insight into behavior of a protein that promotes cancer growth

The neutron reflexometry method has given scientists an atomic-level insight into the behavior of Bcl-2, a protein that promotes cancerous cell growth. The new study was carried out by Umeå chemists in collaboration with the research facilities ESS and ISIS and is published in Nature Communications Biology.

28 Apr 2021

Study reveals mechanisms that cause muscle weakness in patients with Becker disease

Muscle weakness in patients with Becker disease is caused by unusual electrical activity in muscle fibres termed 'plateau potentials' that make them temporarily inactive, says a study published today in eLife.

27 Apr 2021

Researchers use natural polymer coatings to improve bone-implant integration

Traffic accidents, tumor resections, and congenital diseases can cause significant trauma, which can lead to large bone deformations and/or bone loss. Although bone has some capacity to regenerate, large bone defects cannot be healed without major medical procedures.

27 Apr 2021

Scientists identify many genes that are important in fruit flies' neuron development

Neurons result from a highly complex and unique series of cell divisions. For example, in fruit flies, the process starts with stem cells that divide into mother cells (progenitor cells), that then divide into precursor cells that eventually become neurons.

27 Apr 2021

UCI biologists develop new mouse model to study late-onset Alzheimer's disease

University of California, Irvine biologists have developed a new genetically engineered mouse model that, unlike its predecessors, is based on the most common form of Alzheimer's disease.

27 Apr 2021

Researchers design "nanotraps" to capture and destroy SARS-CoV-2 viruses

Researchers at the Pritzker School of Molecular Engineering at the University of Chicago have designed a completely novel potential treatment for COVID-19: nanoparticles that capture SARS-CoV-2 viruses within the body and then use the body's own immune system to destroy it.

27 Apr 2021

Cholestenone could be a new antibacterial drug against H. pylori

Helicobacter pylori (H. pylori), a gram-negative pathogen that has infected half of the world's population is a Group I carcinogen according to the WHO. H. pylori resides in the gastric mucosa causing gastritis, ulcers, gastric cancers and malignant lymphoma of the stomach.

27 Apr 2021

Aigenpulse Launches CytoML 5.2: Automated Flow Cytometry With Unbiased Analysis

Aigenpulse has rolled out an update to its CytoML Experiment Suite – its automated, end-to-end, machine learning solution specifically aimed at streamlining and automating cytometry analysis at scale and replacing manual gating processes.

27 Apr 2021

SARS-CoV-2 suppresses the immune response in the gut

In an effort to determine the potential for COVID-19 to begin in a person's gut, and to better understand how human cells respond to SARS-CoV-2, the scientists used human intestinal cells to create organoids - 3D tissue cultures derived from human cells, which mimic the tissue or organ from which the cells originate.

27 Apr 2021

Research opens up the possibility of dietary therapy for cancer

A research group at the RIKEN Center for Biosystems Dynamics Research (BDR) has discovered molecular events that determine whether cancer cells live or die. With this knowledge, they found that reduced consumption of a specific protein building block prevents the growth of cells that become cancerous.

27 Apr 2021

Researchers map the first complete atlas of single cells that make up the human teeth

Researchers at the University Zurich have mapped the first complete atlas of single cells that make up the human teeth. Their research shows that the composition of human dental pulp and periodontium vary greatly. Their findings open up new avenues for cell-based dental therapeutic approaches.

27 Apr 2021

Drug cocktail can effectively activate and expand muscle stem cells

Skeletal muscle – the type of muscle that attaches to bones and enables movement – is the most abundant tissue in the human body.

27 Apr 2021

Researchers discover elusive cell type in fish sensory organs

One of the evolutionary disadvantages for mammals, relative to other vertebrates like fish and chickens, is the inability to regenerate sensory hair cells.

26 Apr 2021

Life Science News

New compound could alleviate neurological symptoms of CHARGE syndrome

First-of-its-kind method cryopreserves fruit fly embryos in liquid nitrogen

Scientists identify blood cells most likely to be targeted by HIV during a real-life infection

New technique to hyperpolarize and purify fumarate for MRI

Researchers suggest new approach to build a 'nanopore' biosensor for detecting specific molecules

Novel platform has potential to detect many disease-related biomarkers in just one test

Study reveals the role of lncRNAs in immune dysfunction during severe COVID-19

Scientists gain atomic-level insight into behavior of a protein that promotes cancer growth

Study reveals mechanisms that cause muscle weakness in patients with Becker disease

Researchers use natural polymer coatings to improve bone-implant integration

Scientists identify many genes that are important in fruit flies' neuron development

UCI biologists develop new mouse model to study late-onset Alzheimer's disease

Researchers design "nanotraps" to capture and destroy SARS-CoV-2 viruses

Cholestenone could be a new antibacterial drug against H. pylori

Aigenpulse Launches CytoML 5.2: Automated Flow Cytometry With Unbiased Analysis

SARS-CoV-2 suppresses the immune response in the gut

Research opens up the possibility of dietary therapy for cancer

Researchers map the first complete atlas of single cells that make up the human teeth

Drug cocktail can effectively activate and expand muscle stem cells

Researchers discover elusive cell type in fish sensory organs

The future of automation: Machine learning–driven hepatocyte and organoid counting

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

Reimagining light scattering for biotherapeutics

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