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DNA origami used to analyze the ultra-fast movements of CRISPR enzymes

The remarkable genetic scissors called CRISPR/Cas9, the discovery that won the 2020 Nobel Prize in Chemistry, sometimes cut in places that they are not designed to target.

23 Feb 2021

Maturation of 'mini brain' organoids matches human brain development

A new study from UCLA and Stanford University researchers finds that three-dimensional human stem cell-derived 'mini brain' organoids can mature in a manner that is strikingly similar to human brain development.

23 Feb 2021

Study findings help explain the diversity of cancers in different Li-Fraumeni patients

The most frequently mutated gene in human cancers is called p53. Patients with Li-Fraumeni syndrome, which is a rare disorder that increases the risk of developing several types of cancer, often have an increased risk to develop cancers at early ages if they inherit p53 mutations.

23 Feb 2021

Study reveals a potential target for stroke treatment in blood-brain barrier

The blood-brain barrier prevents immune cells from circulating freely in the brain, and the breakdown of its function is a major cause of post-stroke inflammation.

23 Feb 2021

Scientists discover mechanism by which epithelial tumors cause maturation defects

Conducted on the fly Drosophila, the study shows that tumors caused by chromosomal instability delay entry into the adult phase.

23 Feb 2021

Stem cell breakthrough offers hope for critically endangered wildlife species

A paper recently published in the scientific journal Stem Cells and Development shares an important advancement in conservation -- one that may make the difference between survival and extinction for wildlife species that have been reduced to very small population sizes.

23 Feb 2021

Fooling the novel coronavirus with a fake handshake to inactivate the virus

Fool the novel coronavirus once and it can't cause infection of cells, new research suggests.

22 Feb 2021

Study provides better understanding of metabolic routes involved in regulating satiety

Results of the European study SATIN (SATiety INnovation) reveal a relation between certain metabolites in the blood and the satiety perceived after consuming food.

22 Feb 2021

Genetic mechanism enables TB-causing bacterium to remember and rapidly respond to stress

Tuberculosis bacteria have evolved to remember stressful encounters and react quickly to future stress, according to a study by computational bioengineers at Rice University and infectious disease experts at Rutgers New Jersey Medical School (NJMS).

22 Feb 2021

In vivo imaging reveals how anti-CD20 antibodies guide the immune system to attack tumors

Monoclonal antibodies are part of the therapeutic arsenal for eliminating cancer cells. Some make use of the immune system to act and belong to a class of treatment called "immunotherapies." But how do these antibodies function within the tumor? And how can we hope to improve their efficacy?

22 Feb 2021

Researchers expand understanding of hop genome with implications for brewing industry

Oregon State University and U.S. Department of Agriculture researchers have significantly expanded the understanding of the hop genome, a development with important implications for the brewing industry and scientists who study the potential medical benefits of hops.

22 Feb 2021

New project seeks to adapt marine bioproducts into tasty vegan food ideas

Putting innovative Australian marine bioproducts into tasty vegan food ideas is the goal of a new project at the Centre for Marine Bioproducts Development, Flinders University.

22 Feb 2021

Researchers create high throughput arrays of miniaturized 3D tumor models

By engineering common filter papers, similar to coffee filters, a team of NYU Abu Dhabi researchers have created high throughput arrays of miniaturized 3D tumor models to replicate key aspects of tumor physiology, which are absent in traditional drug testing platforms.

22 Feb 2021

Insights into molecular tools shared across coronaviruses could provide potential target for COVID-19

Coronaviruses exploit our cells so they can make copies of themselves inside us. After they enter our cells, they use our cell machinery to make unique tools of their own that help them generate these copies.

22 Feb 2021

Study reveals mechanism for translation of maternally inherited mitochondrial genome

An international collaboration among researchers from Finland, Sweden, UK and the USA has captured ribosomes translating messenger RNA expressed from the maternally inherited mitochondrial genome.

22 Feb 2021

Researchers uncover 'hotspots' on the Spike protein that are critical for SARS-CoV-2 infection

The COVID-19 pandemic has prompted considerable investigation into how the SARS-CoV-2 Spike protein attaches to a human cell during the infection process, as this knowledge is useful in designing vaccines and therapeutics.

22 Feb 2021

Neurons activated by visual stimulus keep more active during subsequent sleep, study shows

When you slip into sleep, it's easy to imagine that your brain shuts down, but University of Michigan research suggests that groups of neurons activated during prior learning keep humming, tattooing memories into your brain.

22 Feb 2021

POU1F1 gene variant linked to pituitary dwarfism in Karelian Bear Dogs

A study carried out at the University of Helsinki investigated pituitary dwarfism in Karelian Bear Dogs and found a link to a variant of the POU1F1 gene. The results can also help understand the gene's significance to the human pituitary gland's development and function.

22 Feb 2021

Study: Quantum mechanics plays a role in biological processes and causes mutations in DNA

Quantum biology is an emerging field of science, established in the 1920s, which looks at whether the subatomic world of quantum mechanics plays a role in living cells.

22 Feb 2021

Novel vectors reduce the risks associated with ocular gene therapies

Strategies based on the use of gene therapy to mitigate the effects of mutations that cause blindness are undergoing rapid development.

22 Feb 2021

Life Science News

DNA origami used to analyze the ultra-fast movements of CRISPR enzymes

Maturation of 'mini brain' organoids matches human brain development

Study findings help explain the diversity of cancers in different Li-Fraumeni patients

Study reveals a potential target for stroke treatment in blood-brain barrier

Scientists discover mechanism by which epithelial tumors cause maturation defects

Stem cell breakthrough offers hope for critically endangered wildlife species

Fooling the novel coronavirus with a fake handshake to inactivate the virus

Study provides better understanding of metabolic routes involved in regulating satiety

Genetic mechanism enables TB-causing bacterium to remember and rapidly respond to stress

In vivo imaging reveals how anti-CD20 antibodies guide the immune system to attack tumors

Researchers expand understanding of hop genome with implications for brewing industry

New project seeks to adapt marine bioproducts into tasty vegan food ideas

Researchers create high throughput arrays of miniaturized 3D tumor models

Insights into molecular tools shared across coronaviruses could provide potential target for COVID-19

Study reveals mechanism for translation of maternally inherited mitochondrial genome

Researchers uncover 'hotspots' on the Spike protein that are critical for SARS-CoV-2 infection

Neurons activated by visual stimulus keep more active during subsequent sleep, study shows

POU1F1 gene variant linked to pituitary dwarfism in Karelian Bear Dogs

Study: Quantum mechanics plays a role in biological processes and causes mutations in DNA

Novel vectors reduce the risks associated with ocular gene therapies

The Proteoform Puzzle: Unlocking the Next Frontier

Synthetic Biology and the Pursuit of Living Diagnostics

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

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