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New model based on combination of GANs with reinforcement learning for drug discovery

Insilico Medicine, a Baltimore-based next-generation artificial intelligence company specializing in the application of deep learning for target identification, drug discovery and aging research announces the publication of a new research paper in Molecular Pharmaceutics journal titled "Adversarial Threshold Neural Computer for Molecular De Novo Design".

10 May 2018

Penn engineers develop faster way to make drug microparticles

Pharmaceuticals owe their effects mostly to their chemical composition, but the packaging of these drugs into specific physical formulations also need to be done to exact specifications.

9 May 2018

Scripps Research professor wins 2018 RSC Bioorganic Chemistry Award

Floyd Romesberg, PhD, professor at The Scripps Research Institute, has won the 2018 Royal Society of Chemistry Bioorganic Chemistry Award for his ground-breaking contributions to the expansion of the genetic alphabet.

9 May 2018

Advances in Cell Lineage Analysis

Dr. Jan Phillip Junker discusses the applications of CRISPR-Cas9 in cell lineage analysis and the development of tomo-seq; a method to study the spatial organization of cells within whole organisms.

9 May 2018

Scientists use X-ray laser to gain insights into structure of Alzheimer's proteins

A new experimental method permits the X-ray analysis of amyloids, a class of large, filamentous biomolecules which are an important hallmark of diseases such as Alzheimer's and Parkinson's.

9 May 2018

Changing metabolic states of intestinal bacteria have an effect on MAIT defense cells

A little-explored group of immune cells plays an important role in the regulation of intestinal bacteria.

9 May 2018

Findings confirm analytical principle that describes mutational processes and cancer development

When a cell develops into a tumor, something has gone terribly wrong: the uncontrolled growth, invasion of nearby tissues and finally metastasis are the result of many consecutive DNA mutations.

9 May 2018

Scientists unlock secrets of extraordinary jumping capability of predatory spiders

Scientists have unlocked the secrets of how some predatory spiders catch their prey whilst hunting by successfully training one to jump different distances and heights for the first time.

8 May 2018

Researchers harness the precision of CRISPR to knock out single genes in yeast

Researchers have used CRISPR-Cas9 to develop a technology that can precisely target any gene in the yeast species Saccharomyces cerevisiae.

8 May 2018

Scientists discover a small family of proteins that control inclusion of DNA methylation marks in genome

Not all of your genome needs to be active at any given time. Some regions are prone to hopping around the genome in problematic ways if left unchecked; others code for genes that need to be turned off in certain cells or at certain times.

8 May 2018

Researchers create a biomaterial that can be used to study the brain

Researchers have created a new type of biomaterial that can support the growth of nerve cells, potentially opening up new possibilities for patients who have experienced a stroke or traumatic brain injury.

8 May 2018

Simplified Mammalian Cell Harvesting without Centrifuging

Centrifuging adds time and can potentially damage the cell sample, Michael Grauf discusses how cell clarification and sterile filtration can be achieved in one step.

From Sartorius 8 May 2018

Scientists make breakthrough in visualizing human brain tissue at microscopic level

A team of scientists from the Li Ka Shing Faculty of Medicine of The University of Hong Kong and Imperial College London has made a breakthrough in the visualization of human brain tissue at the microscopic level.

7 May 2018

Social context has a lot to do with spread of disease

"Patient zero" isn't entirely to blame when an infection takes root in a population. According to Rice University scientists, social context in the community has a lot to do with how a disease spreads.

7 May 2018

TUM researchers unravel mechanism of action for one of pore-forming bacterial toxins

Pore-forming toxins are common bacterial poisons. They attack organisms by introducing holes in cell membranes.

7 May 2018

New tool to track interactions among brain cells in action

It's a neuroscientist's dream: being able to track the millions of interactions among brain cells in animals that move about freely, behaving as they would under natural circumstances. New technology developed at The Rockefeller University represents a big step toward realizing that goal.

7 May 2018

Scientists shed light on formation of new blood vessels

How new blood vessels form in mammals, for example during development or after injury, was so far not known exactly. Scientists at the Goethe University have now been able to shed light on this process.

7 May 2018

OU researchers receive $5.7 million NIH grant to accelerate antibiotic discovery

University of Oklahoma professors, Helen Zgurskaya and Valentin Rybenkov, and team are addressing the challenge and critical need for new antibiotics that can fight infections caused by the multi-drug resistant bacterium, Pseudomonas aeruginosa, considered an urgent threat by the Centers for Disease Control and Prevention.

7 May 2018

Tradeshow Talks with Molbio Diagnostics Ltd

Tradeshow Talks with Molbio Diagnostics Ltd at Health GB 2018.

7 May 2018

Fujitsu announces development of molecular simulation technology for drug discovery

Fujitsu Laboratories Ltd. and Fujitsu Limited today announced the development of molecular simulation technology for drug discovery that can accurately estimate binding affinity, which represents the degree to which proteins that can cause diseases (target proteins) bind to chemical substances that could become candidate drugs.

7 May 2018

Life Science News

New model based on combination of GANs with reinforcement learning for drug discovery

Penn engineers develop faster way to make drug microparticles

Scripps Research professor wins 2018 RSC Bioorganic Chemistry Award

Advances in Cell Lineage Analysis

Scientists use X-ray laser to gain insights into structure of Alzheimer's proteins

Changing metabolic states of intestinal bacteria have an effect on MAIT defense cells

Findings confirm analytical principle that describes mutational processes and cancer development

Scientists unlock secrets of extraordinary jumping capability of predatory spiders

Researchers harness the precision of CRISPR to knock out single genes in yeast

Scientists discover a small family of proteins that control inclusion of DNA methylation marks in genome

Researchers create a biomaterial that can be used to study the brain

Simplified Mammalian Cell Harvesting without Centrifuging

Scientists make breakthrough in visualizing human brain tissue at microscopic level

Social context has a lot to do with spread of disease

TUM researchers unravel mechanism of action for one of pore-forming bacterial toxins

New tool to track interactions among brain cells in action

Scientists shed light on formation of new blood vessels

OU researchers receive $5.7 million NIH grant to accelerate antibiotic discovery

Tradeshow Talks with Molbio Diagnostics Ltd

Fujitsu announces development of molecular simulation technology for drug discovery

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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