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Three papers focus on nucleosomes and may help uncover the rules governing gene transcription

A trio of groundbreaking publications from researchers in Northwestern University's Physical Sciences-Oncology Center (PS-OC) report important methodological advances that will enable a better understanding of how gene expression is regulated, both in normal cells and in cancer cells. This knowledge could lead to the development of more effective therapeutic agents to treat cancer patients.

2 Aug 2012

SPECT/CT with 99mTc-HMPAO-WBC can improve diagnosis of infectious endocarditis

When combined with standard diagnostic tests, functional imaging procedures have been shown to reduce the rate of misdiagnosed cases of infectious endocarditis. According to new research published in the August issue of The Journal of Nuclear Medicine, single photon emission computed tomography (SPECT)/computed tomography (CT) with 99mTc-hexamethylpropleneamine oxime-labeled white blood cells (99mTc-HMPAO-WBC) can improve the diagnosis of infectious endocarditis in hard-to-diagnose cases.

2 Aug 2012

'Global brain connectivity' explains 10% of variance in individual intelligence

When it comes to intelligence, what factors distinguish the brains of the exceptionally smart from those of average humans? As science has long suspected, overall brain size matters somewhat, accounting for about 6.7 percent of individual variation in intelligence. More recent research has pinpointed the brain's lateral prefrontal cortex, a region just behind the temple, as a critical hub for high-level mental processing, with activity levels there predicting another 5 percent of variation in individual intelligence.

2 Aug 2012

Researchers discover genetic process that can restore function to a CF defective protein

Researchers at the University of Iowa Carver College of Medicine have discovered a genetic process that can restore function to a defective protein, which is the most common cause of cystic fibrosis (CF).

2 Aug 2012

Roundup: Investors not shaken by accretive decision in Minn.; Conn. state abortion coverage conflicts with federal regs

Accretive Health got off pretty easy -- at least according to some on Wall Street. The $2.5 million that the Chicago-based firm must pay Minnesota Attorney General Lori Swanson is "relatively immaterial," wrote analysts from Credit Suisse on Tuesday, July 31, as they sized up the settlement announced between the parties.

2 Aug 2012

Diacetyl intensifies damaging effects of beta-amyloid proteins linked to Alzheimer's

A new study raises concern about chronic exposure of workers in industry to a food flavoring ingredient used to produce the distinctive buttery flavor and aroma of microwave popcorn, margarines, snack foods, candy, baked goods, pet foods and other products.

2 Aug 2012

$Cataract surgery reduces rate of fractures in older patients with vision loss$

Cataract surgery reduces rate of fractures in older patients with vision loss

A major study of Medicare beneficiaries shows that the risk of hip fractures was significantly reduced in patients who had had cataract surgery, compared to patients who did not undergo the procedure. Published in the August edition of the Journal of the American Medical Association (JAMA) the researchers believe their study is the first to demonstrate that cataract surgery reduces the rate of fractures in older patients with vision loss.

2 Aug 2012

High maternal choline intake may reduce risk of hypertension and diabetes in babies

New research from Cornell University indicates that pregnant women who increase choline intake in the third trimester of pregnancy may reduce the risk of the baby developing metabolic and chronic stress-related diseases like high blood pressure and diabetes later in life.

2 Aug 2012

CAP publishes revised version of molecular pathology checklist with dedicated section on NGS

The College of American Pathologists (CAP) published a revised version of its molecular pathology checklist with a dedicated section on next generation sequencing (NGS) as part of the new edition of the CAP Laboratory Accreditation Program checklists released July 31, 2012.

2 Aug 2012

Women with vulvodynia more likely to also have other chronic pain conditions

Millions of women suffer from unexplained vulvar pain so severe it can make intercourse, exercise and even sitting unbearable. New research now shows that women with this painful vaginal condition known as vulvodynia are two to three times more likely to also have one or more other chronic pain conditions, including irritable bowel syndrome, fibromyalgia (musculoskeletal pain) and interstitial cystitis (bladder pain).

2 Aug 2012

Researchers unlock genetic secrets of peripheral T-cell lymphomas

Researchers at Mayo Clinic have completed the world's first genome-wide sequencing analysis of peripheral T-cell lymphomas, unlocking the genetic secrets of this poorly understood and highly aggressive cancer of the immune system.

2 Aug 2012

MLK3 protein critical driver of breast cancer cell migration and invasion

By identifying a key protein that tells certain breast cancer cells when and how to move, researchers at Michigan State University hope to better understand the process by which breast cancer spreads, or metastasizes.

2 Aug 2012

Caffeine may help control movement in people with Parkinson's

Caffeine, which is widely consumed around the world in coffee, tea and soft drinks, may help control movement in people suffering from Parkinson's. This is the finding of a study conducted at the Research Institute of the McGill University Health Centre (RI MUHC) that was recently published in Neurology, the official journal of the American Academy of Neurology.

2 Aug 2012

Viewpoints: Romney praises Israeli health care system -- which has an individual mandate; Sebelius and Pelosi hail launch of women's preventive care provisions

At a breakfast fundraiser in Jerusalem on Monday, (Republican presidential candidate Mitt Romney) had nothing but nice things to say about our ally. But in flattering Israel, he raised more doubts about his political abilities. ... he also praised Israel's health care system. "Do you realize what health care spending is as a percentage of the GDP in Israel?" he asked.

2 Aug 2012

Endoscopic vein-graft harvesting technique safe for CABG surgery

Although there have been questions regarding the safety and durability of endoscopic vein graft harvest for coronary artery bypass graft (CABG) surgery, an analysis of data of more than 200,000 patients who underwent CABG surgery found no evidence of a long-term increased risk of death with endoscopic vein graft harvesting compared to open vein-graft harvesting, according to a study in the August 1 issue of JAMA.

1 Aug 2012

House to vote on D.C. abortion measure

The House is scheduled to vote Tuesday under suspension of the rules on legislation that would limit abortions in D.C. Specifically, the measure would ban abortions after 20 weeks of pregnancy, except when the pregnancy is a danger to the life of the mother.

1 Aug 2012

Exercise reduces symptoms of depression in patients with chronic heart failure

Patients with chronic heart failure who participated in exercise training had modest reductions in symptoms of depression after 12 months, compared with usual care, according to a study in the August 1 issue of JAMA.

1 Aug 2012

Mass. lawmakers unveil bill to cut health costs

Massachusetts lawmakers are expected to vote Tuesday on long-awaited legislation to rein in health care costs. The effort, which would put the state again at the forefront of health policy, will be watched by other states looking to control spiraling costs. After months of debate, House and Senate leaders filed a bipartisan compromise bill of more than 350 pages Monday night that would seek to contain health-care costs by setting a target at which overall state health spending should rise.

1 Aug 2012

Patients with multiple colorectal adenomas may carry germline mutations in APC or MUTYH genes

Among patients with multiple colorectal polyps, the prevalence of certain gene mutations varied considerably by polyp count, according to a study in the August 1 issue of JAMA.

1 Aug 2012

USAID releases newest issue of online newsletter

USAID on Friday released Volume 3, Issue 11 of its online newsletter. The issue highlights the XIX International AIDS Conference (AIDS 2012), held in Washington, D.C., last week, and features a recap of the agency's humanitarian response in the Horn of Africa over the past year.

1 Aug 2012

Medical News

Three papers focus on nucleosomes and may help uncover the rules governing gene transcription

SPECT/CT with 99mTc-HMPAO-WBC can improve diagnosis of infectious endocarditis

'Global brain connectivity' explains 10% of variance in individual intelligence

Researchers discover genetic process that can restore function to a CF defective protein

Roundup: Investors not shaken by accretive decision in Minn.; Conn. state abortion coverage conflicts with federal regs

Diacetyl intensifies damaging effects of beta-amyloid proteins linked to Alzheimer's

Cataract surgery reduces rate of fractures in older patients with vision loss

High maternal choline intake may reduce risk of hypertension and diabetes in babies

CAP publishes revised version of molecular pathology checklist with dedicated section on NGS

Women with vulvodynia more likely to also have other chronic pain conditions

Researchers unlock genetic secrets of peripheral T-cell lymphomas

MLK3 protein critical driver of breast cancer cell migration and invasion

Caffeine may help control movement in people with Parkinson's

Viewpoints: Romney praises Israeli health care system -- which has an individual mandate; Sebelius and Pelosi hail launch of women's preventive care provisions

Endoscopic vein-graft harvesting technique safe for CABG surgery

House to vote on D.C. abortion measure

Exercise reduces symptoms of depression in patients with chronic heart failure

Mass. lawmakers unveil bill to cut health costs

Patients with multiple colorectal adenomas may carry germline mutations in APC or MUTYH genes

USAID releases newest issue of online newsletter

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

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