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Health law implementation: McDonnell wants better answers to exchange questions; GAO says some kids may miss out on coverage

Also in the news, the Boston Globe examines the possible impact of the Supreme Court's health law decision on state-federal relations.

25 Jul 2012

LSDF announces $570,000 in awards to support commercialization of new health-related products

The Life Sciences Discovery Fund (LSDF) today announced nearly $570,000 in awards in its inaugural corporate grant program to support commercialization of new health and health-care products by four early-stage Washington-based companies.

25 Jul 2012

New algorithm can help scientists predict gene and drug interactions

Researchers from Mount Sinai School of Medicine have developed a new computational method that will make it easier for scientists to identify and prioritize genes, drug targets, and strategies for repositioning drugs that are already on the market. By mining large datasets more simply and efficiently, researchers will be able to better understand gene-gene, protein-protein, and drug/side-effect interactions. The new algorithm will also help scientists identify fellow researchers with whom they can collaborate.

25 Jul 2012

Dapivirine Phase III trial now underway in Africa to treat HIV in women

A large clinical trial testing the long-term safety and effectiveness of a new approach for preventing HIV in women - a vaginal ring used once a month - is now underway in Africa, researchers announced today at the XIX International AIDS Conference (AIDS 2012).

25 Jul 2012

EMA COMP issues positive opinion to Albireo for A4250

Albireo AB, a biopharmaceutical company specializing in gastroenterology, today announced that the European Medicines Agency Committee for Orphan Medicinal Products (COMP) has issued a positive opinion on an application for orphan medicinal product status for the company's lead hepatology candidate, A4250.

25 Jul 2012

Views on AIDS: The benefits of male circumcision; A more optimistic battle; The need to focus on high-impact prevention strategies

A selection of editorials and op-eds from around the country that focus on the campaign to eradicate HIV.

25 Jul 2012

Insight into possible new approaches in vaccine development for blood-borne infections and HIV

White blood cells called neutrophils, which are the first line of defense against infection, play an unexpected role by boosting antibody production, according to research led by Mount Sinai School of Medicine. The findings suggest neutrophils have multiple roles within the immune system and function at levels previously unknown to the scientific community. The research, published in Nature Immunology, provides groundbreaking insight into possible new approaches in vaccine development for blood-borne infections and HIV.

25 Jul 2012

Hypoxic lung environment increases HIF-2a tumor growth signaling

In addition to the well-known risk factor of smoking, chronic obstructive pulmonary disease (COPD) increases lung cancer risk.

25 Jul 2012

Scientists discover structure and operating procedures of anti-bacterial killing machine

Scientists have discovered the structure and operating procedures of a powerful anti-bacterial killing machine that could become an alternative to antibiotics.

25 Jul 2012

Aeterna Zentaris files request with FDA for Fast Track designation for AEZS-130

Aeterna Zentaris Inc. today announced that it has filed a request with the United States Food and Drug Administration (FDA) for Fast Track designation for its oral ghrelin agonist, AEZS-130, as a diagnostic test for adult growth hormone deficiency (AGHD).

25 Jul 2012

Researchers plan to develop new rehabilitation tool for stroke victims

Researchers at the University of Luxembourg, along with their international partners, want to develop an easy-to-use, self-motivating tool that stroke patients can use in their rehabilitation process. The 4.4 million euro project is funded by the European Commission Seventh Framework Programme.

25 Jul 2012

New classification scheme for psychiatric symptoms

The traditional approach to psychiatric diagnosis is based on grouping patients on the basis of symptom clusters. This approach to diagnosis has a number of problems, as symptoms are not necessarily specific to a single diagnosis.

25 Jul 2012

Colonoscopy with polypectomy decreases colorectal cancer incidence and mortality

A study from researchers in Switzerland found that colonoscopy with polypectomy significantly reduces colorectal cancer incidence and colorectal cancer-related death in the general population.

25 Jul 2012

Favorable results from BioCryst’s ulodesine plus allopurinol Phase 2b trial on gout

BioCryst Pharmaceuticals, Inc. announced favorable 52-week safety results and sustained efficacy from the extension phase of its randomized Phase 2b trial of ulodesine (BCX4208) added to allopurinol in patients with gout who had failed to reach the serum uric acid (sUA) therapeutic goal of <6 mg/dL on allopurinol alone, as well as positive Phase 2 safety results in patients with mild to moderate renal impairment.

25 Jul 2012

Viewpoints: Aurora shootings show need for more aggressive psych treatment; Venture capitalist says health exchanges can curb costs

Looking at guns, looking at video games - that's starting from the wrong perspective. People who commit spree killings are usually suffering from severe mental disorders. The response, and the way to prevent future episodes, has to start with psychiatry, too. The best way to prevent killing sprees is with relationships - when one person notices that a relative or neighbor is going off the rails and gets that person treatment before the barbarism takes control. But there also has to be a more aggressive system of treatment options, especially for men in their 20s.

25 Jul 2012

AmSurg second quarter revenues increase 23% to $231.6 million

Christopher A. Holden, President and Chief Executive Officer of AmSurg Corp., today announced financial results for the second quarter ended June 30, 2012. Revenues for the quarter were $231.6 million, a 23% increase from $187.5 million for the second quarter of 2011.

24 Jul 2012

South Asians have higher levels of blood sugar than Europeans: New diabetes study

A new diabetes study at the University of Leicester has discovered that South Asians (people of Indian, Pakistani, Bangladeshi and Sri Lanka origin) have higher levels of blood sugar than white Europeans independent of risk factors that influence sugar levels.

24 Jul 2012

Merck, Chimerix sign license agreement for CMX157 to treat HIV infection

Chimerix, Inc. today announced the execution of a license agreement granting Merck, known as MSD outside the United States and Canada, exclusive worldwide rights to CMX157, Chimerix's novel lipid acyclic nucleoside phosphonate currently being evaluated to treat HIV infection.

24 Jul 2012

Recent release: Examining next steps for corporate responsibility programs in India

In this post in the Results for Development Institute's "Center for Global Health R&D Policy Assessment" blog, Aarthi Rao, a program officer at the institute, examines whether corporate social responsibility (CSR) programs within Indian pharmaceutical companies can help fight neglected diseases.

24 Jul 2012

New large animal model for human cancer studies

A naturally occurring line of immunodeficient pigs can support the growth of human tumors injected under their skin, offering a promising new large animal model for studying human cancers and testing new drugs and treatment strategies.

24 Jul 2012

Medical News

Health law implementation: McDonnell wants better answers to exchange questions; GAO says some kids may miss out on coverage

LSDF announces $570,000 in awards to support commercialization of new health-related products

New algorithm can help scientists predict gene and drug interactions

Dapivirine Phase III trial now underway in Africa to treat HIV in women

EMA COMP issues positive opinion to Albireo for A4250

Views on AIDS: The benefits of male circumcision; A more optimistic battle; The need to focus on high-impact prevention strategies

Insight into possible new approaches in vaccine development for blood-borne infections and HIV

Hypoxic lung environment increases HIF-2a tumor growth signaling

Scientists discover structure and operating procedures of anti-bacterial killing machine

Aeterna Zentaris files request with FDA for Fast Track designation for AEZS-130

Researchers plan to develop new rehabilitation tool for stroke victims

New classification scheme for psychiatric symptoms

Colonoscopy with polypectomy decreases colorectal cancer incidence and mortality

Favorable results from BioCryst’s ulodesine plus allopurinol Phase 2b trial on gout

Viewpoints: Aurora shootings show need for more aggressive psych treatment; Venture capitalist says health exchanges can curb costs

AmSurg second quarter revenues increase 23% to $231.6 million

South Asians have higher levels of blood sugar than Europeans: New diabetes study

Merck, Chimerix sign license agreement for CMX157 to treat HIV infection

Recent release: Examining next steps for corporate responsibility programs in India

New large animal model for human cancer studies

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

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