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Patients with NK/T-cell lymphomas might benefit from treatment with JAK inhibitors

A substantial proportion of NK/T-cell lymphomas harbor Janus Kinase 3 gene mutations. Patients with these lymphomas might benefit from treatment with a Janus Kinase inhibitor according to a study published in Cancer Discovery, a journal of the American Association for Cancer Research.

16 Jun 2012

Georgia's estimate Medicaid shortfall is $300 million; Texas' independent pharmacists upset by Medicaid transition

The state's Medicaid agency has a projected $300 million hole to fill in next year's budget. If the shortfall remains at that level, the financial request to the General Assembly in January will be "very high" from a historical perspective, said Vince Harris, chief financial officer of the Department of Community Health, after the agency's board meeting Thursday. The projected $308 million shortfall for fiscal 2013 stems mostly from growth in the program's spending.

16 Jun 2012

New approach to drug design may yield more effective and less toxic cancer medicines

A new approach to drug design, pioneered by a group of researchers at the University of California, San Francisco (UCSF) and Mt. Sinai, New York, promises to help identify future drugs to fight cancer and other diseases that will be more effective and have fewer side effects.

16 Jun 2012

Study finds no evidence to support an effect of THC on MS progression

The first large non-commercial study to investigate whether the main active constituent of cannabis (tetrahydrocannabinol or THC) is effective in slowing the course of progressive multiple sclerosis (MS) shows that there is no evidence to suggest this; although benefits were noted for those at the lower end of the disability scale.

16 Jun 2012

Immune system may play a key role in removing Alzheimer's protein

Recent work in mice suggested that the immune system is involved in removing beta-amyloid, the main Alzheimer's-causing substance in the brain. Researchers have now shown for the first time that this may apply in humans.

16 Jun 2012

HCA, HealthONE expand Colorado Center for Robotic Surgery

People who may be considering surgery for a disease or medical condition now have greater access to the most advanced type of minimally invasive procedures available in Colorado. Cherry Creek Shopping Center visitors will be able to "test drive" the new da Vinci Robots in a one-of-a-kind experience on June 18 in the Center's Grand Court.

16 Jun 2012

New model can eradicate childhood obesity in private sector

Sanofi US and the Alliance for a Healthier Generation, a non-profit organization founded by the American Heart Association and the William J. Clinton Foundation, today announced a new model for the private sector to combat childhood obesity.

16 Jun 2012

Civitas commences CVT-301 Phase 2a trial in Parkinson's disease

Civitas Therapeutics, Inc., a privately-held pharmaceutical company developing transformative therapeutics using the ARCUS respiratory delivery platform, announced today the initiation of a Phase 2a clinical trial in Parkinson's disease patients evaluating CVT-301, an inhaled formulation of levodopa (L-dopa), for the rapid relief from motor fluctuations.

16 Jun 2012

Researchers identify three sets of genetic markers linked with CNS PNET

Researchers at The University of Nottingham have identified three sets of genetic markers that could potentially pave the way for new diagnostic tools for a deadly type of brain tumour that mainly targets children.

16 Jun 2012

MHN, MCA partner in recognition of Men's Health Month

In recognition of "Men's Health Month," the Minnesota Chiropractic Association (MCA) is joining the Men's Health Network (MHN), a non-profit educational organization that promotes the health of men and their families, in encouraging men to incorporate a wellness and preventive approach to their healthcare regime.

16 Jun 2012

iPS Academia Japan, Life Technologies partner for induced pluripotent stem cell patent portfolio

Life Technologies Corporation today announced that it has deepened its commitment to stem cell research and its customers by signing a non-exclusive agreement with iPS Academia Japan for its induced pluripotent stem (iPS) cell patent portfolio.

16 Jun 2012

Less expensive ARV combination just as effective for women in developing countries as costlier ARVs, study shows

A new study by researchers at Brigham and Women's Hospital in Boston shows that the less-expensive antiretroviral nevirapine, when used in combination with other antiretroviral drugs (ARVs), is as effective as a more expensive combination among women in developing countries, VOA News reports.

16 Jun 2012

Chemotherapy improves survival for patients with SCLC and LCNEC

Research presented in the July 2012 issue of the International Association for the Study of Lung Cancer's (IASLC) Journal of Thoracic Oncology, concluded that patients with limited large cell neuroendocrine tumors or with limited stage small-cell lung cancer who were treated with perioperative chemotherapy and surgery had better overall survival outcomes than patients treated with surgery alone.

16 Jun 2012

Study identifies new genetic factor associated with lean diabetes

Type 2 diabetes is popularly associated with obesity and a sedentary lifestyle. However, just as there are obese people without type 2 diabetes, there are lean people with the disease.

15 Jun 2012

NextGen commercializes new assay for identification of biomarkers in brain disorders

NextGen Group Plc, the AIM listed company developing its own diagnostics product pipeline and providing diagnostic biomarker development services, announces the commercialisation of a new assay for the identification of diagnostic biomarkers in brain disorders in animal models.

15 Jun 2012

Roundup: Iowa redesign of mental health services raises concerns; Mich. lawmakers opposed to abortion restrictions are 'silenced'

State leaders hope their mental health redesign will bring better services to (rural areas of Iowa), but many front-line administrators doubt they'll see significant improvements soon. In fact, some worry that services could erode over the next year as money and some financial responsibilities are shifted from the counties to the state. Some long-term improvements are possible, they say, but cash likely will run short in the next few months.

15 Jun 2012

Psoriasis TNF-α therapeutic effects mediated by MSC antioxidant reduction

The therapeutic effects of tumor necrosis factor-α inhibitors in psoriasis occur through a reduction in the antioxidant response of mesenchymal stem cells, suggest study findings.

15 Jun 2012

Insulin more effective add-on than sitagliptin in glucose control

Insulin seems to be a more effective add-on regimen than sitagliptin in patients with diabetes inadequately controlled by metformin monotherapy, show study findings.

15 Jun 2012

Anti-TNFs increase risk for herpes zoster infections in IRD patients

Patients with inflammatory rheumatic diseases who are treated with anti-tumor necrosis factor medications are significantly more likely to experience herpes zoster infections than those treated with traditional disease-modifying anti-rheumatic drugs, study results show.

15 Jun 2012

Rheumatism drugs may increase shingles risk

Patients with inflammatory rheumatic disease treated with one of the most effective medicines for their disease face a substantially increased risk for developing shingles, warn European researchers who suggest vaccination may be an option.

15 Jun 2012