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Researchers shed light on key biological events that may lead to new disease treatments

In exploring how proteins interact with crucial DNA sequences to regulate gene activity, researchers have shed light on key biological events that may eventually be manipulated to provide new disease treatments.

8 Jun 2012

Independent evaluation of PMI presented to U.S. Congress

The Center for Global Health and Development (CGHD) at Boston University on Thursday delivered its report on the President's Malaria Initiative (PMI), released in February, to the U.S. Congress, IIP Digital reports, noting the "independent evaluation team finds that the [PMI] has been 'very successful' in reducing children's deaths from the mosquito-borne parasitic disease, but also warns that the program must gear up if those gains are to be sustained."

8 Jun 2012

Lung changes in association with ACPA status are a primary manifestation of RA

A new study presented today at EULAR 2012, the Annual Congress of the European League Against Rheumatism, shows that lung changes in association with anti-citrullinated protein autoantibody (ACPA) status are a primary manifestation of rheumatoid arthritis (RA).

8 Jun 2012

Group rates more than 2,600 hospitals with single letter grade

News outlets report on how their local hospitals were graded by a nonprofit organization that culled patient safety ratings from a variety of sources and assigned a single letter grade to more than 2,600 hospitals in the United States.

8 Jun 2012

Data from abatacept versus adalimumab Phase IIIb comparison study on RA

Data from one of the few head-to-head trials in rheumatoid arthritis (RA) presented today at EULAR 2012, the Annual Congress of the European League Against Rheumatism, demonstrates that at one year, 64.8% of patients receiving abatacept (Orencia) and 63.4% of patients receiving adalimumab (Humira) achieved ACR20.

8 Jun 2012

Survey finds 1 in 10 new cases of TB in China are drug-resistant

"One in 10 cases of tuberculosis in China cannot be treated by the most commonly-used drugs, driven by a lack of testing and misuse of medicine, according to a national survey that showed for the first time the size of the drug-resistant epidemic," the Associated Press reports.

8 Jun 2012

Study packs powerful one-two punch in the fight against heart failure

A new study in the journal Circulation packs a powerful one-two punch in the fight against heart failure. The leading blow: Identification of a unique alliance of proteins that plays a major role in the development of the disease. The second but equally powerful hit: Drugs that interfere with this axis already exist.

8 Jun 2012

Implementing the health law: HHS has missed nearly half of its deadlines

The Hill reports that, according to an analysis by the American Action Forum, the Department of Health and Human Services has missed many implementation deadlines in the last two years. Meanwhile, Politico Pro examines issues related to the health law's Medicaid expansion and exchange subsidies.

8 Jun 2012

Fluorinov Pharma receives OICR grant to develop new drug against blood cancers

The Ontario Institute for Cancer Research (OICR) today announced $1.5 million in funding over three years for the development of a new drug by Toronto-based Fluorinov Pharma, Inc. The drug, called FV-162, is a highly potent, orally-delivered small molecule proteasome inhibitor with significant advantages over drugs currently used to treat multiple myeloma and some forms of Non-Hodgkin's lymphoma.

8 Jun 2012

CSIS publishes report on Advancing Health in Ethiopia

The Center for Strategic & International Studies (CSIS) on Wednesday released a report called "Advancing Health in Ethiopia." The report examines what the U.S. can "realistically expect to achieve in its ongoing engagement in health in Ethiopia" and what the core considerations to guide future U.S. efforts should be, CSIS writes on its website.

8 Jun 2012

Patients over 45 years with history of early menopause 50% less likely to develop severe RA

A new study presented today at EULAR 2012, the Annual Congress of the European League Against Rheumatism, shows that early menopause predicts a milder form of rheumatoid arthritis (RA).

8 Jun 2012

Experimental drug tested against multi-drug resistant TB

"Researchers who tested a novel type of antibiotic against multi-drug-resistant tuberculosis [MDR-TB] are reporting that nearly half of patients who got the new drug cleared the bacteria from their lung fluid in two months," according to a study published Thursday in the New England Journal of Medicine, Reuters reports.

8 Jun 2012

Cardinal Health to launch new technology enhancements at SNM annual meeting

At the Society of Nuclear Medicine's (SNM) 59th Annual Meeting in Miami Beach, Fla., June 9-12, Cardinal Health will introduce new technology enhancements that make it possible for hospital nuclear medicine departments and imaging centers to seamlessly improve data integration and the overall efficiency of their operations.

8 Jun 2012

Experts debate whether spinal manipulation for neck pain should be abandoned

The effectiveness of spinal manipulation divides medical opinion. On bmj.com today, experts debate whether spinal manipulation for neck pain should be abandoned.

8 Jun 2012

Politico examines implications of Senate's draft farm bill on maritime industry, food aid

Politico examines the implications of the Senate's draft farm bill on the maritime industry, noting the industry "makes much of its money on foreign-aid shipments, courtesy of the Department of Agriculture and the U.S. Agency for International Development," and writing, "The Senate's farm bill extends Food for Peace, the largest international food-aid program for the next five years but pulls $40 million a year from shipments to go toward cash grants and the purchase of food in local markets."

8 Jun 2012

Nrf2-KEAP1 protein may play a role in diabetic retinopathy

A Wayne State University researcher believes a protein that fails to reach the nucleus of retinal cells may play a role in causing eye disease in people with diabetes.

8 Jun 2012

More federal scrutiny for Minn. Medicaid program; Colo. Medicaid reforms signed into law

Minnesota's Medicaid program faces more federal scrutiny on its rates. In the meantime, new Medicaid payment reforms are signed into law in Colorado.

8 Jun 2012

New study into pain associated with diabetes

Researchers in Sheffield have been awarded over £310,000 to carry out a study that could help revolutionise the way clinicians treat the pain experienced by thousands of people with diabetes.

8 Jun 2012

Tp53 genetic mutation may play an important role in prostate cancer

A team of UC Davis investigators has found that a genetic mutation may play an important role in the development of prostate cancer. The mutation of the so-called p53 (or Tp53) gene was previously implicated in late disease progression, but until now has never been shown to act as an initiating factor. The findings may open new avenues for diagnosing and treating the disease.

8 Jun 2012

Political will, health concerns, increased funding driving family planning in Africa, report says

The Nairobi-based African Institute for Development Policy on Tuesday presented a report called "Africa on the Move!" at the Woodrow Wilson International Center for Scholars in Washington, VOA News reports, noting the report "says that in some African countries, political will, maternal and child health concerns as well as more and more funding are helping to develop effective family planning."

8 Jun 2012