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Enrollment complete in Advaxis’ ADXS-HPV Phase 2 study on CIN 2/3

Advaxis, Inc., a leader in developing the next generation of immunotherapies for cancer and infectious diseases, announced today that it has completed enrollment of 40 patients in the second of three dose cohorts in Lm-LLO-E7-07, a randomized, single blind, placebo controlled Phase 2 dose escalation study assessing the safety and efficacy of ADXS-HPV for the treatment of cervical intraepithelial neoplasia (CIN) 2/3.

7 Jun 2012

Astute Medical announces completion of $40.4M Series C financing

Astute Medical, Inc., a developer of novel, biomarker-based medical diagnostics, today announced the completion of a $40.4 million Series C financing led by MPM Capital and including new investor Kaiser Permanente Ventures.

7 Jun 2012

CDI introduces MyCell Services

Cellular Dynamics International, Inc. (CDI), the world's largest commercial producer of human induced pluripotent stem (iPS) cell lines and tissue cells, today announced the launch of its MyCell Services.

7 Jun 2012

Streamline Health first quarter revenues increase to $5,445,000

Streamline Health Solutions, Inc. today announced financial results for the first quarter of fiscal year 2012, ended April 30, 2012.

7 Jun 2012

First Edition: June 7, 2012

Today's headlines include a report that some lawmakers on Capitol Hill are meeting to attempt to find ways to deal with an upcoming deadline -- Jan. 1 -- which is also known as the "fiscal cliff."

7 Jun 2012

Clinical study shows positive effects of CAD106 vaccine against AD

A study led by Karolinska Institutet in Sweden reports for the first time the positive effects of an active vaccine against Alzheimer's disease. The new vaccine, CAD106, can prove a breakthrough in the search for a cure for this seriously debilitating dementia disease. The study is published in the distinguished scientific journal Lancet Neurology.

7 Jun 2012

Hospitals get graded for patient safety

Hospital executives are about to find out if they make the grade under a new rating system developed by the Leapfrog Group that debuts online Wednesday - and some are not happy about it. Under Leapfrog's Hospital Safety Score initiative, hospitals are given a letter grade - A, B, C, D or F - on how safely they treat patients. The grade reflects patient injuries, infection rates and the frequency of medical and medication errors.

7 Jun 2012

Neurotech’s ADNS-300 system obtains European CE Mark approval

Neurotech s.a., a Belgium based developer and manufacturer of neurostimulation devices, announces that it has obtained the European CE Mark for its ADNS-300 system dedicated to the treatment of refractory epilepsy.

7 Jun 2012

WHO warns of drug-resistant strains of gonorrhea

"Drug-resistant strains of gonorrhea have spread to countries across the world, the U.N. health agency said on Wednesday, and millions of patients may run out of treatment options unless doctors catch and treat cases earlier," Reuters reports.

7 Jun 2012

Biologic treatments reduce mortality risk in patients with rheumatoid arthritis

According to a study presented today at EULAR 2012, the Annual Congress of the European League Against Rheumatism, patients with rheumatoid arthritis (RA) who are prescribed biologic treatments have a significantly lower mortality risk (adjusted hazard ratio [HR]: 0.61) than those just treated with traditional disease modifying anti-rheumatic drugs (DMARDs).The study also found the mortality was similar irrespective of the method of action of biologics (anti-tumour necrosis factor drugs [anti-TNFs] or rituximab).

7 Jun 2012

Disney to ban junk food ads in obesity fight

The change from the children's entertainment company got a prominent backer Tuesday as First Lady Michelle Obama offered her praise for the move.

7 Jun 2012

Study finds some possible shortfalls in screening methods for female athlete triad

Female athletes, particularly those involved in high level college sports at the NCAA Division I level, are particularly prone to a trio of medical issues called the "female athlete triad." A new study conducted by sports medicine researchers at the Medical College of Wisconsin found there are some possible shortfalls in the methods used to screen these athletes for the triad, and that could put athletes at risk for lifelong health problems.

7 Jun 2012

Blog examines WHO funding

In this globalhealthpolicy.net blog post, Andrew Harmer, a research fellow at the London School of Hygiene and Tropical Medicine, examines funding for the World Health Organization, highlighting two documents circulated as background reading for the just-concluded World Health Assembly.

7 Jun 2012

Young adults, adolescents with mental health disorders more likely to become long-term opioid users

Long-term use and abuse of opioid painkillers, such as OxyContin and Vicodin, has markedly increased in the United States in the last two decades. Of note, prescription opioids constitute 86.9 percent of prescription drug misuse among high school students. And last week in a two-day U.S. Food and Drug Administration public meeting, officials questioned the use of long-term opioids for chronic pain due to a lack of evidence for the effectiveness and concerns about the potential risk for addiction.

7 Jun 2012

Dengue fever vaccine 'may be in sight,' Reuters reports

Reuters reports on efforts to develop a vaccine for dengue fever, writing that "victory over ... the intensely painful 'breakbone fever' ... may be in sight." Paris-based firm Sanofi "hopes for positive results in September from a key trial among children in Thailand that would set it on course to market a shot in 2015, which would prevent an estimated 100 million cases of dengue infection each year," the news service writes.

7 Jun 2012

Clinical study demonstrates effectiveness of vismodegib in treating BCNS

A revolutionary clinical study has demonstrated the effectiveness of a new drug, vismodegib, in dramatically shrinking and preventing the formation of basal cell skin cancers - the most common cancer in the United States - in patients with basal cell nevus syndrome (BCNS), a rare genetic condition that causes hundreds to thousands of skin cancers primarily treated by surgical removal.

7 Jun 2012

Appropriate CT scans may save and extend lives of children

The American College of Radiology (ACR) urges that results of a study (Pearce et al) to be published in the Lancet regarding radiation risk from pediatric computed tomography (CT) scans should not keep parents from getting needed medical imaging care for their children, but should be discussed with their physician and factored into their shared decision making before an imaging scan is performed.

7 Jun 2012

Paper spotlights unique developmental strategy undertaken by all mammals

Ask the average person the street how the brain develops, and they'll likely tell you that the brain's wiring is built as newborns first begin to experience the world. With more experience, those connections are strengthened, and new branches are built as they learn and grow. A new study conducted in a Harvard lab, however, suggests that just the opposite is true.

7 Jun 2012

CBO: Ballooning health care costs will continue as a key driver in nation's debt

A new Congressional Budget Office report offers a bleak view of the future if current tax and spending policies are not adjusted.

7 Jun 2012

Targeting stem cells might be more effective in treating vascular disease

One of the top suspects behind killer vascular diseases is the victim of mistaken identity, according to researchers from the University of California, Berkeley, who used genetic tracing to help hunt down the real culprit.

7 Jun 2012