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T2M cells play a crucial role in treatment-resistant asthma

For most people with asthma, a couple of puffs from an inhaler filled with steroids makes breathing easy. But if their lungs become resistant to the calming effect of that medicine, they live in fear of severe asthma attacks that could send them to the hospital - or worse. Now, new research from the University of Michigan Health System may help explain what's going on in the lungs of these steroid-resistant individuals. The findings could aid the development of new treatment options, and of better ways to identify people at risk of becoming steroid-resistant.

8 May 2012

Researchers discover CD19 pathway that leads to lymphoma

Researchers studying the molecular signals that drive a specific type of lymphoma have discovered a key biological pathway leading to this type of cancer. Cancerous cells have been described as being "addicted" to certain oncogenes (cancer-causing genes), and the new research may lay the groundwork for breaking that addiction and effectively treating aggressive types of B cell lymphoma.

8 May 2012

Declining biodiversity may contribute to rise in asthma, allergies

Declining biodiversity may be contributing to the rise of asthma, allergies, and other chronic inflammatory diseases among people living in cities worldwide, a Finnish study suggests. Emerging evidence indicates that commensal microbes inhabiting the skin, airway, and gut protect against inflammatory disorders. However, little is known about the environmental determinants of the microbiome.

8 May 2012

Nautilus first quarter net sales increase 6.1% to $51.3 million

Nautilus, Inc. reported today its unaudited operating results for the first quarter ended March 31, 2012.

8 May 2012

New data from Acucela’s ACU-4429 Phase 2a trial on advanced dry AMD/geographic atrophy

Acucela Inc., a clinical-stage biotechnology company focused on developing new treatments for blinding eye diseases, announced today that the first patient data from the ACU-4429 program were presented during a poster session at The Association for Research in Vision and Ophthalmology (ARVO) 2012 Annual Meeting.

8 May 2012

KSW releases Krames On-Demand Version 6.0

Krames StayWell (KSW) has announced the newest release of its award-winning patient education program Krames On-Demand Version 6.0.

8 May 2012

Clinverse closes $3.8 million Series B round of funding

Clinverse, Inc., the global cloud-based ecommerce platform provider for clinical trials, announced today that it has closed a $3.8 million Series B round of funding led by Hatteras Venture Partners of Durham, NC. Vital Financial of Bethesda, MD, also participated in this funding round.

8 May 2012

Zinc oxide could increase risk of skin cancer

As vacationers prepare to spend time outdoors this summer, many of them will pack plenty of sunscreen in hopes it will protect their bodies from overexposure, and possibly from skin cancer. But researchers at Missouri University of Science and Technology are discovering that sunscreen may not be so safe after all.

8 May 2012

Otsuka announces results from aripiprazole Phase 3 trial on schizophrenia

Otsuka Pharmaceutical Co., Ltd. and H. Lundbeck A/S today announced results from a Phase 3 clinical trial evaluating the efficacy, safety and tolerability of once-monthly aripiprazole intramuscular (IM) depot formulation for the maintenance treatment of adults with schizophrenia.

8 May 2012

Baxter declares quarterly dividend of $0.335 per common share

The Board of Directors of Baxter International Inc. today declared a quarterly dividend of $0.335 per Baxter common share.

From Baxter International Inc. 8 May 2012

Specific proteins can help identify patients with IBS

Irritable bowel syndrome (IBS) is hard to diagnose as well as treat, but researchers at the Sahlgrenska Academy, at the University of Gothenburg, Sweden, have discovered a way of confirming the disorder using stool samples.

8 May 2012

Affymax first quarter total revenue increases to $63.2 million

Affymax, Inc. today reported financial results for the first quarter ended March 31, 2012. The net income for the first quarter of 2012 was $31.5 million (or $0.87 per share) compared to a net loss of $9.6 million (or $(0.36) per share) for the first quarter of 2011.

8 May 2012

State roundup: Calif. fight over group homes for seniors; New agency proposed to police disabled care in NY; Conn. retiree health plan expansion could endanger protections

Neighbors were already concerned about the growing number of group homes for the elderly and recovering addicts in the area, many of them for profit. A Times analysis found 24 licensed facilities offering residential care for the elderly within a mile of the proposed project and three more waiting for state approval. It is one of several such clusters that have emerged in Los Angeles County -- including parts of the San Fernando Valley and South Bay -- where families can afford fees that run into thousands of dollars per month. Large swaths of the county's less affluent areas have no such facilities.

8 May 2012

Hologic features minimally invasive technologies at ACOG annual clinical meeting

Hologic, Inc., a leading developer, manufacturer and supplier of premium diagnostics products, medical imaging systems and surgical products dedicated to serving the healthcare needs of women, is featuring minimally invasive technologies in surgical, diagnostic and skeletal health at The American College of Obstetricians and Gynecologists (ACOG) annual clinical meeting.

From Hologic, Inc. 7 May 2012

Health Canada announces labelling update for Cipralex

Health Canada is informing Canadians of a labelling update for the prescription drug Cipralex (the brand name of the drug escitalopram) regarding a dose-related risk of abnormal heart rhythms. Cipralex is used to treat depression and belongs to a family of drugs known as Selective Serotonin Reuptake Inhibitors (SSRIs).

7 May 2012

NIH responds to criticism over handling of controversial bird flu studies

In a letter dated April 25, Amy Patterson, associate director for science policy in the office of the director of the National Institutes of Health, "has refuted criticism of the way a meeting held to allow a biosecurity advisory group to review controversial bird flu studies was handled," denying "the agenda was crafted to achieve a predetermined outcome," the Canadian Press/Winnipeg Free Press writes.

7 May 2012

Low weight gain reported among women with nausea and vomiting of pregnancy

In one of the largest studies of its kind, clinicians and researchers with Carolinas HealthCare System found that nearly 25% of women with nausea and vomiting of pregnancy (NVP) reported weight gain below recommended levels for their pre-pregnancy body mass index (PPBMI).

7 May 2012

Various combinations of biomarkers are required to unequivocally diagnose specific disease

With a range of diseases, doctors need unique features which they can use to unequivocally identify a patient's illness for an appropriate diagnosis. Scientists therefore search for the biomarkers for an illness or a combination of biomarkers, known as biosignatures, which are as easy as possible to measure.

7 May 2012

Healthy newborns should not be over-protected against natural exposure of gut flora

Infants whose gut is colonised by E. coli bacteria early in life have a higher number of memory B cells in their blood, reveals a study of infants carried out at the Sahlgrenska Academy at the University of Gothenburg, Sweden.

7 May 2012

Satellite-guided plan to effectively control tsetse fly

For the first time, scientists have created a satellite-guided plan to effectively control the tsetse fly - an African killer that spreads "sleeping sickness" disease among humans and animals and wipes out $4.5 billion in livestock every year.

7 May 2012