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Genetically modified mouse mimics key features of Charcot-Marie-Tooth disease

A team of scientists from the University of Missouri created a genetically modified mouse that mimics key features of Charcot-Marie-Tooth disease, an inherited neuromuscular disease affecting approximately 150,000 people in the United States.

18 Apr 2012

New text on nursing of autism spectrum disorder

The growing number of children and adults on the autism spectrum represent a growing need for quality health care that is sensitive to the issues they face. This is the premise and challenge behind a new text, Nursing of Autism Spectrum Disorder: Evidence-based Integrated Care across the Lifespan (Springer, April 2012), edited by Dr. Ellen Giarelli, an associate professor in Drexel's College of Nursing and Health Professions, with Dr. Marcia Gardner.

18 Apr 2012

Federal officials use health law to cite two insurers for excessive premium increases

The insurance companies will be able to charge the higher amount, but they will be required to disclose on websites that reviewers found the rates to be unreasonable and explain why they are still imposing them.

18 Apr 2012

FDA's three draft guidances on biosimilars - BIO submits comments

The Biotechnology Industry Organization (BIO) submitted comments yesterday to the U.S. Food and Drug Administration (FDA) on three draft guidance documents on biosimilar products.

18 Apr 2012

MD Anderson develops series of food plate worksheets on nutrition and cancer prevention

As part of National Minority Cancer Awareness Week during April 15 to 21, The University of Texas MD Anderson Cancer Center has developed a series of food plate worksheets that focus on nutrition and cancer prevention for African American, Hispanic and Vietnamese audiences.

18 Apr 2012

Medical journals facing raft of ethical, transparency challenges

The New York Times, Connecticut Mirror and MedPage Today examine how prominent journals are handling questions about their independence or integrity.

18 Apr 2012

Early intervention of biologic therapies improves outcome for Crohn's disease

A large-scale study of medical claims data shows that introducing sophisticated biologic therapies early in the course of treatment for Crohn's disease improves response to medication and reduces the need for surgery.

18 Apr 2012

Medgenics seeks IND approval to initiate EPODURE Biopump Phase IIb anemia study in ESRD patients

Medgenics, Inc., the developer of a novel technology for the sustained production and delivery of therapeutic proteins in patients using their own tissue, today announced that it has filed an Investigational New Drug application with the U.S. Food and Drug Administration to initiate a Phase IIb multi-center, 100-patient clinical trial.

18 Apr 2012

NSCLC drug regimen approved in 2006 does not improve survival for older patients

Analysis of a drug regimen approved by the F.D.A. in 2006 for the treatment of non-small cell lung cancer (bevacizumab added to the standard chemotherapy regimen carboplatin and paclitaxel) finds Medicare insured patients age 65 years and older who received this regimen did not have improved survival compared to patients who received the standard treatment of carboplatin and paclitaxel alone, according to a study in the April 18 issue of JAMA.

18 Apr 2012

Excessive alcohol use associated with lower self-reporting of maturity

Tipping back one too many cocktails during an individual's early 20s doesn't correlate to a personal sense of immaturity; however if this habit doesn't stop as they reach age 30, young adults can feel psychologically underdeveloped, according to a University of Missouri study. Helping young adults acknowledge their mental impulse to "sober up" as they mature can improve substance abuse intervention programs.

18 Apr 2012

U.S. Chamber of Commerce finds small business owners wary of health law regs

The survey finds that the regulations rank at the top of small business owners' concerns. In other news, the National Journal examines the future of accountable care organizations.

18 Apr 2012

Kaposi's sarcoma-associated herpesvirus senses and reacts to host cell's impending death

A research team led by Children's National Medical Center has identified a trigger that causes latent Kaposi's sarcoma-associated herpesvirus (KSHV) to rapidly replicate itself. KSHV causes Kaposi's sarcoma, primary effusion lymphoma, and other cancers that commonly affect immunocompromised patients, including those with AIDS.

18 Apr 2012

Autologous HSPPC-96 vaccine clinically beneficial for GBM patients

Study results from a Phase II multicenter clinical trial tracking the impact that autologous heat shock protein-peptide vaccine (HSPPC-96) has on recurrent glioblastoma multiforme (GBM) patients showed that such a vaccine may be clinically beneficial.

18 Apr 2012

Voluntary testing, counseling for HIV decreases unprotected sex acts among cocaine, heroin users

Voluntary testing and counseling (VT/C) for HIV or sexually transmitted infections (STI) among cocaine and heroin users who were treated in the emergency department (ED), accompanied by referral to drug treatment, was associated with reduction in unprotected sex acts and fewer sex acts while high according to researchers from Boston University School of Medicine (BUSM) and Boston Medical Center (BMC).

18 Apr 2012

IMRT facilitates radiation dose escalation without compromising long-term morbidity for prostate cancer

In an analysis of three different types of radiation therapy used to treat localized prostate cancer, compared with conformal radiation therapy, intensity-modulated radiation therapy (IMRT) was associated with fewer diagnoses of gastrointestinal adverse effects, hip fractures, and receipt of additional cancer treatments but more erectile dysfunction, while proton therapy was associated with more gastrointestinal adverse effects than IMRT.

18 Apr 2012

A guide to catch and treat hypertension early in children

High blood pressure in children and adolescents is a growing health problem that is often overlooked by physicians, according to a University of Michigan Health System article published in American Family Physician that offers doctors a guide to catching and treating hypertension early.

18 Apr 2012

FDA to regulate smartphone medical applications; Companies to enter $4 billion insurance exchange market

An onslaught of mobile health technology has forced an arranged marriage between smartphone app makers and the Food and Drug Administration -- because someone had to regulate them. There's just one problem: Many of the tech wizards aren't used to FDA supervision. And now, both sides are struggling to figure out how to live with each other.

18 Apr 2012

Engineered particles tied to penetratin discover, deliver ligands for mitochondria, ribosomes

Scientists who developed a technology for identifying and targeting unique protein receptor ZIP Codes on the cellular surface have found a way to penetrate the outer membrane and deliver engineered particles - called iPhage - to organelles inside the cell.

18 Apr 2012

Study explains why women are more prone to knee injuries than men

Women are more prone to knee injuries than men, and the findings of a new study suggest this may involve more than just differences in muscular and skeletal structure - it shows that males and females also differ in the way they transmit the nerve impulses that control muscle force.

18 Apr 2012

Innovative model of breast cancer rehabilitation

The Prospective Surveillance Model, an innovative new model of breast cancer rehabilitation, is featured in a special supplement to the American Cancer Society's journal, Cancer released on April 6, 2012. The model addresses the numerous physical issues faced by women with breast cancer and offers hope for an improved quality of life for all women with breast cancer through rehabilitation and exercise.

18 Apr 2012

Medical News

Genetically modified mouse mimics key features of Charcot-Marie-Tooth disease

New text on nursing of autism spectrum disorder

Federal officials use health law to cite two insurers for excessive premium increases

FDA's three draft guidances on biosimilars - BIO submits comments

MD Anderson develops series of food plate worksheets on nutrition and cancer prevention

Medical journals facing raft of ethical, transparency challenges

Early intervention of biologic therapies improves outcome for Crohn's disease

Medgenics seeks IND approval to initiate EPODURE Biopump Phase IIb anemia study in ESRD patients

NSCLC drug regimen approved in 2006 does not improve survival for older patients

Excessive alcohol use associated with lower self-reporting of maturity

U.S. Chamber of Commerce finds small business owners wary of health law regs

Kaposi's sarcoma-associated herpesvirus senses and reacts to host cell's impending death

Autologous HSPPC-96 vaccine clinically beneficial for GBM patients

Voluntary testing, counseling for HIV decreases unprotected sex acts among cocaine, heroin users

IMRT facilitates radiation dose escalation without compromising long-term morbidity for prostate cancer

A guide to catch and treat hypertension early in children

FDA to regulate smartphone medical applications; Companies to enter $4 billion insurance exchange market

Engineered particles tied to penetratin discover, deliver ligands for mitochondria, ribosomes

Study explains why women are more prone to knee injuries than men

Innovative model of breast cancer rehabilitation

Advancing Menopause Care: Non-Hormonal Treatments for Vasomotor Symptoms

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

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