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Tool predicts response to platinum-based chemotherapy in ovarian cancer

A DNA repair pathway-focused score has the potential to help determine if first-line platinum based chemotherapy can benefit advanced-stage ovarian cancer patients, according to a study published April 13 in the Journal of the National Cancer Institute.

16 Apr 2012

TGF-β molecule ramps up the immune system in some cases and suppress it in others

Loyola researchers are reporting surprising findings about a molecule that helps ramp up the immune system in some cases and suppress it in others.

16 Apr 2012

New drug to detect beta-amyloid plaques may help diagnose AD earlier

Use of a new drug to detect the beta-amyloid plaques in the brain that are hallmark signs of Alzheimer's disease may help doctors diagnose the disease earlier, according to research that will be presented as part of the Emerging Science program (formerly known as Late-Breaking Science) at the American Academy of Neurology's 64th Annual Meeting in New Orleans April 21 to April 28, 2012.

16 Apr 2012

High blood sugar in combination with high insulin levels causes fatty deposits in the heart

The impaired substrate metabolism of diabetes patients is often expressed in an increase in fatty deposits in the cells of the heart muscle. Until now, the exact cause of this was unknown. Now, researchers at the MedUni Vienna in the Division of Endocrinology and Metabolism of MedUni Vienna in cooperation with the MR Centre of Excellence Vienna have shown that high blood sugar in combination with high levels of insulin - not an influx of fats - results in such deposits within a few hours.

16 Apr 2012

MDI to advance Detect-Ready MRSA Panel with $1.9M Series B recapitalization financing

Molecular Detection Inc., a company developing Detect-Ready® tests designed to increase the speed and accuracy of infectious disease diagnosis, today announced that it has completed a $1.9 million Series B recapitalization financing.

16 Apr 2012

First Edition: April 16, 2012

Today's headlines include reports about what the future might look like when Medicare doctors' pay will be tied to quality and cost of care, as well as how consumer advocates are anxious about a key aspect of the health law.

16 Apr 2012

Neurological symptoms due to a bump on the head should not be ignored

When Dr. Irene Gatti de Leon slipped on the ice and bumped her head, she wasn't too concerned. But two months later, she began to experience weakness in her right leg and right arm while she and her husband were visiting their daughter in suburban Chicago.

16 Apr 2012

Seminar series on issues related to intervention, implementation science in aging

A seminar series focusing on issues related to intervention and implementation science in aging is the latest interdisciplinary initiative at the Johns Hopkins University School of Nursing (JHUSON) Center for Innovative Care in Aging.

16 Apr 2012

Gene function preserved despite structural differences in the DNA

Chloroplasts, the plant cell's green solar power generators, were once living beings in their own right. This changed about one billion years ago, when they were swallowed up but not digested by larger cells. Since then, they have lost much of their autonomy.

16 Apr 2012

Panel discussion on personalized medicine at USciences

Advances in fields such as genetics and genomics have created new opportunities for personalized medicine applications in clinical practice and the healthcare delivery. This integration raises important questions about how personalized medicine can best help patients without increasing costs and improving health outcomes.

16 Apr 2012

'Mental health checkups' as part of health care in schools

"The early detection of children who are showing psychiatric symptoms or are at the risk of a mental disorder is crucial, but introducing "mental health checkups" as part of health care in schools is not altogether simple," says David Gyllenberg, MD, whose doctoral dissertation "Childhood Predictors of Later Psychotropic Medication Use and Psychiatric Hospital Treatment - Findings from the Finnish Nationwide 1981 Birth Cohort Study" was publically examined at the University of Helsinki on 13 April 2012.

16 Apr 2012

Sebelius appeals to civil rights groups for health law support

Health and Human Services Secretary Kathleen Sebelius asked civil rights activists to help defend the health law. Meanwhile, other news outlets report on specific aspects of the law, including how contractors have been preparing for its implementation, and the latest on accountable care organizations.

16 Apr 2012

Changes in thromboxane synthase may lead to hypertension in women with preeclampsia

Virginia Commonwealth University School of Medicine researchers have discovered that changes in the gene expression of a key enzyme may contribute to high blood pressure and increase susceptibility to forming blood clots in pregnant women with preeclampsia.

16 Apr 2012

As fiscal years start to wind down, states confront Medicaid issues

Although their tax revenue has improved substantially since the worst of the recession, states continue to face severe fiscal challenges as they are called on to spend more because of the economic stress caused largely by continued high unemployment. Many states face increasing caseloads for Medicaid, the combined federal-state health program for the poor and disabled.

16 Apr 2012

Implantable device with alert modes warns users about potential heart attack

More than 30% of the one million heart attack victims in the United States each year die before seeking medical attention. Although widespread education campaigns describe the warning signs of a heart attack, the average time from the onset of symptoms to arrival at the hospital has remained at 3 hours for more than 10 years.

16 Apr 2012

House GOP dusts off old budget ideas to replace some automatic cuts

When they return to Capitol Hill next week, Republicans on key House committees are expected to take up earlier proposals as they look for ways to replace some of the automatic budget cuts scheduled to take effect in January. Members of the House Judiciary Committee will make another go at revamping medical liability laws.

16 Apr 2012

Neurosurgeons from NYU Langone to present at AANS annual meeting

Neurosurgeons from NYU Langone Medical Center will present research and discuss surgical approaches and use of new technologies to treat neurosurgical conditions at the annual meeting of the American Association of Neurological Surgeons (AANS), held April 14-18, 2012 in Miami Beach, FL.

16 Apr 2012

DEP exposure suppresses function of phagocytic immune cells

A team of researchers, led by Dr. Stephan Schwander, of the University of Medicine and Dentistry of New Jersey - School of Public Health (UMDNJ-SPH), has determined a possible link between exposure to a common component of urban air pollution and a change in the function of important immune cells that protect against the bacteria that cause tuberculosis.

16 Apr 2012

Contraception, Medicare, Medicaid hot-button topics in stump speeches

Political news coverage included a fact check of a Mitt Romney claim and more on the stay-at-home mom controversy.

16 Apr 2012

SMART Heart improves cardiovascular surgical outcomes

Two years ago, 57-year-old Allus Brown underwent a simultaneous heart-kidney transplant and spent months in and out of the hospital after battling dilated cardiomyopathy, a condition that enlarges and weakens the heart. Now fully recovered, Brown is still in and out of Northwestern Memorial Hospital's Bluhm Cardiovascular Institute each week. Only nowadays when he visits, he's laughing it up, playing board games, and sharing accounts of his own struggles with heart disease as part of the Bluhm Institute's new and innovative program, SMART Heart, stress management and recreational therapy for heart patients.

16 Apr 2012