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Roundup: Calif. county mum on probe of Medicaid managed care firm; Suit alleges substandard care for Ariz. prisoners

A Ventura County commission is trying to keep secret the details of a state-ordered investigation into the management and claims procedures of a healthcare plan designed to serve the county's neediest residents. Complaints about alleged late payments and poor management prompted the Department of Health Care Services to request that auditors step in and examine the plan's financial condition and claims practices. Gold Coast Health Plan was launched last year to switch an estimated 110,000 Ventura County Medi-Cal beneficiaries into an HMO-style healthcare plan.

8 Mar 2012

Women with multiple pregnancies may have reduced risk of MS

Women who have multiple pregnancies may have a lower risk of developing multiple sclerosis (MS), according to research published in the March 7, 2012, online issue of Neurology, the medical journal of the American Academy of Neurology.

8 Mar 2012

Ordinary fat cells can be reengineered to burn calories

In the war against obesity, one's own fat cells may seem an unlikely ally, but new research from the University of California, San Francisco (UCSF) suggests ordinary fat cells can be reengineered to burn calories.

8 Mar 2012

Researchers identify key molecular player in mouse model of kidney disease

In findings that may lead to clinical trials of a promising new drug for kidney disease, researchers at Beth Israel Deaconess Medical Center (BIDMC) and their colleagues have identified a key molecular player and shown how a targeted experimental drug can reverse kidney damage in mouse models of diabetes, high blood pressure, genetic kidney disease, and other kidney injuries.

8 Mar 2012

Sperm only react to changes in calcium concentration

Sperm have only one aim: to find the egg. The egg supports the sperm in their quest by emitting attractants. Calcium ions determine the beating pattern of the sperm tail which enables the sperm to move. Together with colleagues from the Max Planck Institute for the Physics of Complex Systems in Dresden and the University of G-ttingen, scientists from the caesar research centre in Bonn, an institute of the Max Planck Society, have discovered that sperm only react to changes in calcium concentration but not to the calcium concentration itself.

8 Mar 2012

Combining radiation therapy with ipilimumab shows promise against melanoma

Research published today in the New England Journal of Medicine by scientists at the Ludwig Institute for Cancer Research (LICR) and Memorial Sloan-Kettering Cancer Center (MSKCC) showed that combining targeted radiation therapy with immunotherapy (ipilimumab), fostered a strong immune response and a favorable clinical outcome in a patient with melanoma, the most dangerous form of skin cancer.

8 Mar 2012

Study uncovers neural mechanism that links repeated stress with impaired memory

Anyone who has ever been subject to chronic stress knows that it can take a toll on emotions and the ability to think clearly. Now, new research uncovers a neural mechanism that directly links repeated stress with impaired memory.

8 Mar 2012

March issue of NeuroPerspective reviews therapeutics for ADHD

NeuroPerspective, the independent, monthly review of the neurotherapeutics area, has released its March issue, which reviews the field of therapeutics for Attention Deficit Disorder.

8 Mar 2012

People with tinnitus can benefit from internet-based therapy

Those suffering from nagging tinnitus can benefit from internet-based therapy just as much as patients who take part in group therapy sessions. These are the findings of a German-Swedish study in which patients with moderate to severe tinnitus tried out various forms of therapy over a ten-week period.

8 Mar 2012

Researchers document unknown biological mechanism in the blood-brain barrier

Researchers at the University of Copenhagen have documented a previously unknown biological mechanism in the brain's most important line of defence: the blood-brain barrier. Scientists now know that the barrier helps maintain a delicate balance of glutamate, a vital signal compound in the brain.

8 Mar 2012

First 'theranostic' agent for treatment of ALL

A team of researchers at Case Western Reserve University School of Medicine has developed the first "theranostic" agent for the treatment of acute lymphoblastic leukemia (ALL).

8 Mar 2012

NMR techniques shed new light on how pharma molecules adopt different polymorphic forms

Scientists at the University of Warwick have used state-of-the-art nuclear magnetic resonance (NMR) techniques to shed new light on how pharmaceutical molecules pack together in the solid state.

8 Mar 2012

Sosei initiates SO-1105 Phase I trial in oropharyngeal candidiasis

Sosei Group Corporation, the biopharmaceutical company, today announces that its wholly owned Japanese subsidiary, Sosei Co., Ltd., has initiated a Japanese Phase I trial for SO-1105 for the treatment of oropharyngeal candidiasis.

8 Mar 2012

Medtech acquires Camelot Healthcare Training Institute

Camelot Healthcare Training Institute, a post-secondary nursing and allied health care education provider in Central Florida, has been acquired by Medtech College. Camelot now joins the Medtech family of schools and will become Medtech College once appropriate state approvals have been obtained.

8 Mar 2012

Lilly, Boehringer Ingelheim announce availability of Jentadueto tablets

Boehringer Ingelheim Pharmaceuticals, Inc. and Eli Lilly and Company today announced Jentadueto (linagliptin/metformin hydrochloride) tablets are now available by prescription in many leading chain and independent pharmacies across the U.S.

8 Mar 2012

Zalicus fourth quarter revenue decreases to $8.2 million

Zalicus Inc. today reported financial results for the fourth quarter and year ended December 31, 2011.

8 Mar 2012

Researchers make significant strides in the study of Intrahepatic Cholangiocarcinoma

Researchers at the University of Rochester Medical Center's James P. Wilmot Cancer Center have made significant strides in the study of a primary cancer of the liver- Intrahepatic Cholangiocarcinoma (IHCC), also called biliary tract cancer.

8 Mar 2012

Researchers validate CatB protease as target for Alzheimer's

Researchers at the University of California, San Diego, the Medical University of South Carolina, the University of Cincinnati, and American Life Science Pharmaceuticals of San Diego have validated the protease cathepsin B (CatB) as a target for improving memory deficits and reducing the pathology of Alzheimer's disease (AD) in an animal model representative of most AD patients.

8 Mar 2012

BioLineRx receives European patent for BL-1020 to treat schizophrenia

BioLineRx, a biopharmaceutical development company, announced today that a European patent has been granted claiming BL-1020's composition and its use for the treatment of schizophrenia.

8 Mar 2012