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Impact of Personal Genomics Study to launch data collection phase

As genetic risk information plays an increasingly important role in the diagnosis and treatment of many diseases, private companies have made personal genomic testing for these risk factors widely available to the public. However, very little data has been gathered to understand the motivations and expectations of consumers of personal genomic services, the psychological and behavioral impact of these services, and the associated ethical, legal and social issues—until now.

4 Apr 2012

Study: Functional link between two major causes of treatment failure in breast cancer

Research from The Cancer Institute of New Jersey (CINJ) shows a functional link between two major causes of treatment failure in breast cancer, showing the protein behind one of these causes plays a role in increasing the drug resistance properties of the other.

4 Apr 2012

Oral fluoroquinolones increase risk of retinal detachment

In an analysis of a cohort that included nearly one million patients who had visited an ophthalmologist, patients who were taking oral fluoroquinolones had a higher risk of developing a retinal detachment, a serious eye condition, compared with nonusers, although the absolute risk was small, according to a study in the April 4 issue of JAMA.

4 Apr 2012

OvaScience completes $37M Series B financing

OvaScience, a fertility company focused on the discovery, development and commercialization of novel treatments for infertility, today announced that it has completed a $37 million Series B financing.

4 Apr 2012

First Edition: April 4, 2012

In today's headlines, President Barak Obama goes on attack against GOP presidential hopeful Mitt Romney and the Republican budget blueprint; a federal court judge asks for clarifications regarding Obama's comment on judicial activism and the high court's consideration of the health law; as well as reports that doctors are stepping into the effort to curb unnecessary medical treatments.

4 Apr 2012

Obama attacks GOP budget on Medicare changes, entitlement spending cuts

In what has been described as a searing speech, President Barack Obama charged that the GOP budget would end Medicare "as we know it," and included GOP presidential hopeful Mitt Romney in his criticisms.

4 Apr 2012

Study examines alcohol and drugs use patterns in adolescents

A survey of a nationally representative sample of U.S. teenagers suggests that most cases of alcohol and drug abuse have their initial onset at this important period of development, according to a report published in the April issue of Archives of General Psychiatry, a JAMA Network publication.

4 Apr 2012

India must focus on food supply chain to improve malnutrition rates

The cause of malnutrition in India -- which "results in a loss of productivity, indirect losses from impaired cognitive development, and losses from increased long-term health care costs" -- is "not so much a lack of nutrient-rich food, but rather a weakness in the food supply chain," William Thomson, a research assistant at the U.S. Naval War College, writes in an opinion piece in The Diplomat.

4 Apr 2012

Higher-spending hospitals do have better outcomes for emergency patients

Higher-spending hospitals do have better outcomes for their emergency patients, including fewer deaths, according to a Vanderbilt study released as a working paper through the National Bureau of Economic Research.

4 Apr 2012

Haitian cholera epidemic no place for 'good-guy/bad-guy distinctions'

In this Reuters opinion piece, finance blogger Felix Salmon responds to a New York Times (NYT) article published on Monday in which journalist Deborah Sontag examines the global response to Haiti's cholera epidemic.

4 Apr 2012

Researchers identify how neural cells build up resistance to opioid pain drugs within hours

Researchers at the University of Montreal's Sainte-Justine Hospital have identified how neural cells are able to build up resistance to opioid pain drugs within hours. "A better understanding of these mechanisms will enable us to design drugs that avoid body resistance to these drugs and produce longer therapeutic responses, including prolonged opioid analgesia", lead author Dr. Graciela Pineyro said.

4 Apr 2012

Norway study raises new U.S. mammogram overdiagnosis questions

An analysis showing significant mammogram overdiagnosis in Norway has raised new questions about mammograms in the U.S., where some say the overdiagnosis problem could be more rampant because of how early most women begin getting them.

4 Apr 2012

First study to evaluate treatment based on molecular profiling of advanced pancreatic cancer

The feasibility of selecting treatment based on individual molecular characteristics was demonstrated in a first-of-its kind pancreatic cancer clinical trial reported today by the Translational Genomics Research Institute (TGen) and the Virginia G. Piper Cancer Center at Scottsdale Healthcare.

4 Apr 2012

Obama confident the health law will be upheld

In his first public comments about the law since last week's Supreme Court oral arguments, President Barack Obama not only defended the measure and maintained confidence that it would not be overturned, but he also offered warnings against judicial activism.

4 Apr 2012

Tai Chi improves cardiovascular function and body strength in older adults

Exercise which can achieve both cardiovascular function and muscle strength "would be a preferred mode of training for older persons", say investigators.

4 Apr 2012

IPS examines efforts to end FGM in Liberia

Inter Press Service examines efforts to end female genital mutilation (FGM) in Liberia. "Through cooperative efforts with traditional leaders, the government of Liberia is quietly moving to ... bring an end to female genital cutting in Liberia," IPS writes.

4 Apr 2012

Multimarker molecular stool test for colon cancer unaffected by medication, lifestyle factors

Research on an investigational DNA methylation test for colorectal cancer demonstrated that the only clinical variable that influenced test results was age, according to results presented at the AACR Annual Meeting 2012, held here March 31 - April 4.

4 Apr 2012

Health law action at the high court takes a political toll

Findings from a new poll indicate that the public felt less favorable about both the health law and the Supreme Court after last week's oral arguments.

4 Apr 2012

Combination treatment shows promise against NSCLC patients ineligible for bevacizumab

A combination of nab-paclitaxel and carboplatin for the treatment of non-small cell lung cancer may be a promising option for patients ineligible for treatment with bevacizumab, according to data presented at the AACR Annual Meeting 2012, held here March 31 - April 4.

4 Apr 2012

New County Health Rankings released

Researchers found distinct regional patterns: They reported that excessive drinking rates were highest in the Northern states, while rates of teen births, sexually transmitted infections and children in poverty were highest in the South.

4 Apr 2012