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TAK-875 - an emerging therapy for Type 2 diabetes

In a trial of 426 patients with Type 2 diabetes, TAK-875 reduced blood sugar below a pre-determined level in as much as 48 percent of those receiving it after 12 weeks, compared with 40 percent of those who took glimepiride, the older drug, according to findings published online by The Lancet medical journal. The research was presented in June at the American Diabetes Association’s annual meeting in San Diego.

28 Feb 2012

Stents not more beneficial than medications in stable coronary artery disease: Study

The placement of a stent to repair a narrowed artery in the heart has become routine worldwide. A new analysis of earlier clinical trials shows that inserting a stent has no benefit over standard medical care in treating stable coronary artery disease.

28 Feb 2012

Low levels of omega-3 in blood ‘ups’ risk of dementia and brain aging: Study

Researchers looked at 1,575 adults who averaged 67 years old and had no signs of dementia and had not had a stroke. They were given MRI brain scans and a battery of tests to measure memory and thinking abilities; they also had blood drawn to check the level of docosahexaenoic acid (DHA) or omega-3 fatty acids in their red blood cells. Those with the lowest levels of omega-3s showed signs of accelerated aging. They had lower brain volume, indicating shrinkage comparable to two additional years of aging. Compared with those with the highest blood levels of omega-3s, they scored lower on cognitive tests measuring such things as memory, problem solving, abstract thinking and multi-tasking.

28 Feb 2012

Active video games do not increase exercise in kids

Active video games have been promoted to help kids be more physically active. But a new study finds that having active video games in the home may not translate into more exercise.

28 Feb 2012

Adolescents more sensitive to effects of sport-related concussions

Research results published in Brain Injury by Universit- de Montr-al neuropsychologist Dave Ellemberg reveal that adolescents are more sensitive to the effects of a sport-related concussion than adults or children.

28 Feb 2012

ICON announces acquisition of PriceSpective

ICON plc, a global provider of outsourced development services to the pharmaceutical, biotechnology and medical device industries, today announced the acquisition of PriceSpective LLC, a global leader in value strategy consulting.

28 Feb 2012

New guidelines for detection of rheumatic heart disease

The inaugural international guidelines for the diagnosis of rheumatic heart disease (RHD), a disease that affects tens of millions of people worldwide, have today been published by the World Heart Federation in Nature Reviews Cardiology.

28 Feb 2012

Lantronix selects ADI's iCoupler technology to enable new wireless communication devices

Analog Devices, Inc. (ADI) today announced that Lantronix, Inc. has selected ADI's iCoupler digital isolator technology to enable its new family of wireless communication network servers.

28 Feb 2012

DBV receives FDA Fast Track Designation for Viaskin Peanut clinical development program

DBV Technologies announced today that it has received "Fast Track Designation" for the Clinical Development Program of its Viaskin Peanut, a product designed for the treatment by Epicutaneous Immunotherapy (EPIT) of patients with peanut allergy.

28 Feb 2012

IU report supplies close examination of EU's reformed chemicals law

U.S. industry and environmental groups agree that the Toxic Substances Control Act (TSCA) of 1976 needs to be modernized to better protect public health and the environment. However, there is no consensus on what the reform should look like.

28 Feb 2012

CNRS/Inserm researchers discover new family of anti-cancer compounds

A French-Italian team headed by researchers from CNRS and Inserm has discovered a new family of compounds that could make it possible to treat numerous cancers, particularly brain tumors and skin cancers.

28 Feb 2012

Initial stent implantation does not appear to improve outcomes for patients with stable CAD

A meta-analysis of eight previously published clinical trials suggests that initial stent implantation for patients with stable coronary artery disease is not associated with improved outcomes compared with initial medical therapy for prevention of death, nonfatal heart attacks, unplanned revascularization or angina, according to a study published in the Feb. 27 Archives of Internal Medicine, one of the JAMA/Archives journals.

28 Feb 2012

Study sheds light on why physicians mistakenly believe that poor people sue more often

Contrary to the common perception among physicians that poor people sue doctors more frequently, Ramon L. Jimenez from the Monterey Orthopaedic and Sports Medicine Institute and his team demonstrate that socioeconomically disadvantaged patients, in fact, tend to sue physicians less often.

28 Feb 2012

Dompé enters definitive agreement to acquire Anabasis

Dompé, one of Italy's leading biopharmaceutical companies, announced today that it has entered into a definitive agreement to acquire 100% of Anabasis Srl, a privately held Italian research and development biopharmaceutical company, focused on ocular diseases.

28 Feb 2012

Heat-related deaths in football players triple to nearly three per year between 1994-2009

Heat-related deaths among football players across the country tripled to nearly three per year between 1994 and 2009 after averaging about one per year the previous 15 years, according to an analysis of weather conditions and high school and college sports data conducted by University of Georgia researchers.

28 Feb 2012

Scientists discover new pathway necessary for infection to occur with N. gonorrhoeae

Researchers from Boston University School of Medicine (BUSM) have for the first time identified a novel pathway that is necessary for infection to occur with the pathogen Neisseria gonorrhoeae, which is responsible for the second most common infectious disease worldwide, gonorrhea.

28 Feb 2012

Blog examines sale of fake malaria drugs in Tanzania

In this post in Malaria Free Future's "Malaria Matters" blog, Bill Brieger, a professor in the health systems program of the Department of International Health at Johns Hopkins University, examines recent discoveries of fake malaria medications being sold in Tanzania.

28 Feb 2012

Insights into how fructose may contribute to development of obesity, diabetes

A group of scientists from across the world have come together in a just-published study that provides new insights into how fructose causes obesity and metabolic syndrome, more commonly known as diabetes.

28 Feb 2012

Behavioral intervention appears to reduce WC among obese patients

A physical activity and diet program implemented by health educators in physician offices appears to be associated with modest reductions in waist circumference among obese patients, according to a report published Online First by Archives of Internal Medicine, one of the JAMA/Archives journals.

28 Feb 2012

Aid group warns of cholera surge as Haiti enters rainy season

"A Haiti aid group warns on the eve of the rainy season that the Caribbean nation will likely see a surge in cholera cases," the Associated Press/Seattle Times reports.

28 Feb 2012