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PolyTherics, Spirogen enter research collaboration to produce novel ADCs for treatment of cancer

PolyTherics Limited, a provider of solutions to enable the development of better biopharmaceuticals, and Spirogen Limited, a leading oncology-focused company developing DNA sequence-targeted agents, announce that they have formed a research collaboration to develop antibody drug conjugates that combine PolyTherics' proprietary site-specific conjugation chemistry with Spirogen's highly potent novel cytotoxic drugs to produce novel ADCs for the treatment of cancer.

2 Apr 2012

Medicaid long-term care restrictions tighten

The Wall Street Journal offers tips on how to preserve some assets while attempting to qualify for Medicaid assistance.

2 Apr 2012

Special fatty molecules pave novel way to treat infections, autoimmune diseases, allergies and cancer

An international research team led by scientists from Singapore Immunology Network (SIgN) under the Agency of Science, Technology and Research (A*STAR) discovered that a special class of fatty molecules is essential for activating a unique group of early-responding immune cells.

2 Apr 2012

Safe method for destroying cancer cells using death cap mushroom poison

The mere thought of an identification error sends a chill down the spine of any mushroom lover: The death cap mushroom (Amanita phalloides), which resembles the common white button mushroom, contains one of the most deadly poisons found in nature, α-amanitin.

2 Apr 2012

CompCare's 2011 revenues increase to $71,210,000

Comprehensive Care Corporation, a leading behavioral health, substance abuse and psychotropic pharmacy management services provider for managed care companies throughout the U.S., is pleased to announce that its revenues for 2011 more than doubled to $71,210,000 compared to revenues of $35,214,000 in 2010.

2 Apr 2012

IPT has an ongoing protective effect against malaria in infants

Malaria infections among infants can be cut by up to 30 per cent when antimalarial drugs are given intermittently over a 12 month period, a three-year clinical trial in Papua New Guinea has shown.

2 Apr 2012

New technology prevents stone migration during procedures to retrieve urinary stones

Boston Scientific Corporation announces the launch of its BackStop Gel, a new technology designed to prevent stone migration during procedures used to break up and retrieve urinary stones.

2 Apr 2012

Eisai, University of Kansas grant water-soluble pro-drug technology patent to OneWorld Health

OneWorld Health (OWH), a nonprofit that develops lifesaving medicines for neglected diseases, announced that it has signed a nonexclusive patent agreement with Eisai Co., Ltd., for a water-soluble pro-drug technology patent. OWH will use the pro-drug technology to advance development of iOWH032, its new drug to treat acute secretory diarrhea.

2 Apr 2012

Democrats offer optimistic take on court's health law decision

Appearing on the Sunday talk shows, Vice President Joseph Biden and Sen. Charles Schumer, D-N.Y., defended the health law and predicted it would be upheld by the high court.

2 Apr 2012

Biotage adds Isolera Spektra to Flash Chromatography product line

Biotage, a leading global supplier of solutions and technology for analytical and medicinal chemistry, introduced Isolera Spektra. The new Isolera Spektra expands the scope of application of Biotage's market-leading Flash Chromatography product line by increasing efficiency with significant solvent and time saving capabilities as well as enabling purity assessment technology.

2 Apr 2012

Teva reports successful outcome of three debut financings

Teva Pharmaceutical Industries Limited announced today that it successfully priced its debut EUR 1 billion and CHF 450 million debt offerings, and that it entered into a JPY 100 billion senior unsecured fixed-rate syndicated term loan facility.

2 Apr 2012

Sleep enhances emotionally positive memories

Sleep plays a powerful role in preserving our memories. But while recent research shows that wakefulness may cloud memories of negative or traumatic events, a new study has found that wakefulness also degrades positive memories. Sleep, it seems, protects positive memories just as it does negative ones, and that has important implications for the treatment of post-traumatic stress disorder.

2 Apr 2012

Political cartoon: 'Second Guessing?'

Kaiser Health News provides a fresh take on health policy developments with "Second Guessing?" by Mike Smith.

2 Apr 2012

Rare T follicular helper cells essential for developing antibody responses to infectious agents

The characterisation of a rare immune cell's involvement in antibody production and ability to 'remember' infectious agents could help to improve vaccination and lead to new treatments for immune disorders, say researchers from the Walter and Eliza Hall Institute.

2 Apr 2012

Targeting inflammatory pathways may lead to new therapies

Scientists at Fox Chase Cancer Center have uncovered more details about how defects in components of the machinery that makes new proteins can lead to blood and other cancers.

2 Apr 2012

New York Times examines global response to Haiti's cholera epidemic

The New York Times examines the global response to Haiti's cholera epidemic, writing that while "[m]any health officials consider the cholera response 'pretty remarkable,' as John Vertefeuille, the Centers for Disease Control and Prevention's director in Haiti, said ... [o]thers ... believe the bar for success was set too low and more lives could have been saved."

2 Apr 2012

TYRX enrolls 1000th patient in CITADEL/CENTURION AIGISRx Antibacterial Envelope studies

TYRX, Inc., the leader in the commercialization of implantable medical devices designed to help reduce surgical-site infections (SSIs) associated with cardiovascular implantable electronic devices (CIEDs), announced today that the 1000th patient has been enrolled into the CITADEL & CENTURION clinical studies evaluating the company's AIGISRx Antibacterial Envelope.

2 Apr 2012

ulrich medical releases enhancements to spinal implant portfolio

ulrich medical USA, Inc. today announced the release of two important product line enhancements to their growing spinal implant portfolio of expandable cage technologies.

2 Apr 2012

Novel tetracyclines with improved potency, efficacy against contemporary P. aeruginosa isolates

Tetraphase Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company focused on next-generation antibiotics, announced today that it is presenting new results from studies that demonstrate the improved potency and pharmacokinetics of several of its newest discovery-stage tetracycline analogs.

2 Apr 2012

Study sheds light on cellular mechanisms involved in flu resistance

Scientists from the University of Utah School of Medicine have discovered that a mouse protein called IFITM3 contributes to the body's defense against some types of viral infections by binding to an enzyme responsible for regulating the pH of a cell's waste disposal system.

2 Apr 2012

Medical News

PolyTherics, Spirogen enter research collaboration to produce novel ADCs for treatment of cancer

Medicaid long-term care restrictions tighten

Special fatty molecules pave novel way to treat infections, autoimmune diseases, allergies and cancer

Safe method for destroying cancer cells using death cap mushroom poison

CompCare's 2011 revenues increase to $71,210,000

IPT has an ongoing protective effect against malaria in infants

New technology prevents stone migration during procedures to retrieve urinary stones

Eisai, University of Kansas grant water-soluble pro-drug technology patent to OneWorld Health

Democrats offer optimistic take on court's health law decision

Biotage adds Isolera Spektra to Flash Chromatography product line

Teva reports successful outcome of three debut financings

Sleep enhances emotionally positive memories

Political cartoon: 'Second Guessing?'

Rare T follicular helper cells essential for developing antibody responses to infectious agents

Targeting inflammatory pathways may lead to new therapies

New York Times examines global response to Haiti's cholera epidemic

TYRX enrolls 1000th patient in CITADEL/CENTURION AIGISRx Antibacterial Envelope studies

ulrich medical releases enhancements to spinal implant portfolio

Novel tetracyclines with improved potency, efficacy against contemporary P. aeruginosa isolates

Study sheds light on cellular mechanisms involved in flu resistance

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

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