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Aspirin-like drugs help prevent spread of tumors in the body

Australian scientists have made a breakthrough which could help in the fight against cancer. The team from Peter MacCallum Cancer Centre in Melbourne has found a link between non-steroidal anti-inflammatory drugs (NSAIDs), such as aspirin, and the ability of tumours to spread in the body. They say that doctors have been aware of the benefits of NSAIDs for many years, but did not fully understand the biological processes involved.

14 Feb 2012

Postoperative radiotherapy does not really help elderly lung cancer patients

A controversial radiation treatment for patients who've had lung cancer surgery may not help elderly people live longer, U.S. researchers have found. Postoperative radiotherapy, or PORT, is thought to cut the chances that a tumor will return. But it can damage the heart and lungs, which might cancel out any potential benefits -- particularly in the elderly.

14 Feb 2012

Gene sequencing could identify genetic variants of lung cancer and colorectal cancer

Foundation Medicine Inc., a molecular information company that brings comprehensive cancer gene analysis to routine clinical care, and Dana-Farber Cancer Institute have come up with the results from their collaborative next-generation sequencing (NGS) study to assay cancer-relevant genes in 24 non-small cell lung cancer (NSCLC) and 40 colorectal cancer (CRC) cases.

14 Feb 2012

Juvenile arthritis affected kids are at a high risk of cancer: Study

A new study shows that kids with juvenile idiopathic arthritis develop cancer four times more often than children without the disease, but the treatments they receive - including biologic treatments like Enbrel - may not explain their increased risk. If confirmed, researchers say the findings should ease fears that biologic treatments known as TNF inhibitors cause cancer in children and young adults.

14 Feb 2012

What is the optimum amount of sleep for kids?

New research shows that children are getting less sleep than they need. According to an article published online Monday by the journal Pediatrics, 32 sets of sleep guidelines for kids – containing 360 distinct recommendations for children of specific ages – were published between 1897 and 2009. During that time, the amount of recommended sleep fell by an average of 0.71 minutes per year. That added up to about 70 fewer minutes of suggested nightly sleep over the course of the 20th century.

14 Feb 2012

Epigenetic mechanisms maintain tolerance in T cells specific for self antigens

At the most basic level, the immune system must distinguish self from non-self, that is, it must discriminate between the molecular signatures of invading pathogens (non-self antigens) and cellular constituents that usually pose no risk to health (self-antigens).

14 Feb 2012

Scientific conference on considerations for NBCD regulatory approval pathway

The U.S. Food and Drug Administration (FDA) is currently working toward implementing the Biologics Price Competition and Innovation Act (BPCI) of 2009, which establishes an abbreviated approval pathway for biological products that are demonstrated to be "highly similar" to or "interchangeable" with a drug regulated under the Public Health Service Act.

14 Feb 2012

National Library of Medicine acquires papers of sickle cell disease expert

The National Library of Medicine of the National Institutes of Health (NIH), the world's largest medical library, announced recently the acquisition of the papers of Charles F. Whitten, M.D., distinguished professor of pediatrics and associate dean of medicine emeritus at Wayne State University. Whitten passed away in 2008.

14 Feb 2012

Gaming and technology may help control weight and promote health in children

Children are naturally drawn toward gaming and other types of technology, creating an ideal opportunity to design interactive media tools to encourage physical activity and promote healthy eating habits, according to an article in a special issue of the journal Childhood Obesity celebrating the second anniversary of First Lady Michelle Obama's Let's Move! initiative.

14 Feb 2012

Kowa announces data of LIVALO vs. Crestor on pharmacodynamics of warfarin

Kowa Pharmaceuticals America, Inc. today announced data assessing the effect of LIVALO (pitavastatin) compared with Crestor (rosuvastatin) on steady-state pharmacodynamics (PD) of warfarin by measuring international normalized ratio (INR) in healthy adult subjects.

14 Feb 2012

Unstructured free play, recess need to be reinstated in schools

Evaluating the Let's Move! Initiative, Dr. Melinda Sothern, Professor of Public Health and Jim Finks Chair of Health Promotion at LSU Health Sciences Center New Orleans, calls First Lady Michelle Obama brave for taking on the challenge of childhood obesity and suggests that she now consider working to move it up to the policy level.

14 Feb 2012

Foreign Policy examines India's growing industry of fertility treatment

Foreign Policy examines "India's flourishing fertility treatment business," a multi-billion dollar industry that "has earned India the dubious reputation of being the world's baby factory."

14 Feb 2012

New light on treatment targets for potentially life-threatening cardiac arrhythmia conditions

That flutter in your heart may have more to do with the movement of sodium ions than the glance of a certain someone across a crowded room.

14 Feb 2012

'Targeted' drugs may be effective against lung and colorectal tumors driven by novel gene abnormalities

Novel gene abnormalities discovered in a subpopulation of lung and colorectal tumors could potentially identify patients with a good chance of responding to highly specific "targeted" drugs already in use for treating other cancers, scientists report.

14 Feb 2012

Mich. Attorney General to sue administration on birth control rule

While officials at some hospitals and universities expressed support for Obama administration's compromise last week, other religious and governmental leaders remained unsatisfied, according to media reports.

14 Feb 2012

Abbott's Tacrolimus assay provides consistent medication monitoring for organ transplant patients

A new study published in the journal Clinical Chemistry reported Abbott's ARCHITECT Tacrolimus assay provides accurate and consistent medication monitoring for patients taking tacrolimus, an immunosuppressive medication, after receiving solid organ transplantation.

14 Feb 2012

Examining Romney's 'shift' on birth control mandate, other campaign news

Mitt Romney's conservative credentials on birth control are examined through the lens of a Massachusetts state law similar to the birth control mandate President Obama has proposed. In other campaign news, Rick Santorum continues his "Romneycare" assault, and The Associated Press analyzes how Obama's birth control compromise affects the campaign.

14 Feb 2012

Healthy, loving relationship is good for the heart

Being involved in a healthy, loving relationship is good for the heart, says Vanderbilt Heart and Vascular Institute cardiologist Julie Damp, M.D.

14 Feb 2012

Ugandan government announces $3M plan to fight nodding disease

"The growing threat of nodding disease and increased pressure for action has spurred the Ugandan government to announce a $3 million (USD) plan to address the mystery illness," Global Health Frontline News reports, adding, "Initial funds will be used to set up screening centers and treat those affected in Pader, Kitgum, and Lamwo districts in northern Uganda as early as this month."

14 Feb 2012

Machine-learning methods show that patients with severe brain injury could communicate accurately

Only by employing complex machine-learning techniques to decipher repeated advanced brain scans were researchers at NewYork-Presbyterian/Weill Cornell able to provide evidence that a patient with a severe brain injury could, in her way, communicate accurately.

14 Feb 2012