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Proactive test-and-treat case-detection strategy can combat malaria

As researchers work to eliminate malaria worldwide, new strategies are needed to find and treat individuals who have malaria, but show no signs of the disease. The prevalence of asymptomatic or minimally symptomatic malaria can be as high as 35 percent in populations with malaria and these asymptomatic individuals can serve as a reservoir for spreading malaria even in areas where disease transmission has declined.

7 Feb 2012

Merck completes two suvorexant Phase III trials on insomnia

Merck, known as MSD outside the United States and Canada, today provided an update on the development program for suvorexant, the company's investigational orexin receptor antagonist, which, if approved, will be a new mechanism for the treatment of insomnia.

7 Feb 2012

Ovid and LWW journals Technical Services team earns BenchmarkPortal certification

Wolters Kluwer Health is pleased to announce that its Ovid and LWW journals Technical Services team received certification as a Center of Excellence by BenchmarkPortal in collaboration the Center for Customer-Driven Quality, founded at Purdue University. Only 10% of companies that submit data under BenchmarkPortal's program are awarded a "Certification of Excellence."

7 Feb 2012

Women with higher mammographic density more likely to develop breast cancer

A new study analyses the influence that certain birth and infancy characteristics have on mammographic density - an important indicator of breast cancer risk. The results reveal that women born to mothers aged over 39 years and women who were taller and thinner than the average girl prior to puberty have a higher breast density. This brings with it an increased risk of developing breast cancer.

7 Feb 2012

State roundup: Legislatures, govs juggling costs and health programs

Medicaid spending is a matter of urgency almost everywhere in the country right now, but in few places is the urgency as palpable as it is here, where the governor refers to the federal-state health insurance program for the poor as "welfare," says it's necessary to eliminate coverage for 65,000 adults, and wants to stop paying room and board for some 2,000 elders who live in group homes. All these ideas are part of Republican Governor Paul LePage's plan to close a $220 million hole in the state's biennial Medicaid budget.

7 Feb 2012

TGen to host Pediatric Cancer Translational Genomics in Scottsdale

The Translational Genomics Research Institute (TGen) will host Pediatric Cancer Translational Genomics Feb. 6-8 at the Hotel Valley Ho in Scottsdale, bringing together more than 150 leading pediatric cancer researchers, clinicians and foundations to promote the exchange of information and ideas for advancing pediatric cancer research and treatment.

7 Feb 2012

U.N. supporting yellow fever vaccination campaigns in Cameroon, Ghana

Following an outbreak of the mosquito-borne yellow fever virus in Cameroon that has infected at least 23 people and killed at least seven people, U.N. and local officials are working to vaccinate "1.2 million people considered at high risk of contracting yellow fever, which has no cure," the U.N. News Centre reports.

7 Feb 2012

LE strips can rapidly diagnose periprosthetic joint infection

Rothman Institute at Jefferson joint researchers continue to seek better ways to diagnose and subsequently treat periprosthetic joint infection (PJI) in patients following total joint arthroplasty. Their latest research shows leukocyte esterase reagent (LE) strips, common in diagnosing urinary tract infections, can also have a role in rapid diagnosis of PJI.

7 Feb 2012

Closing the 'cancer divide' between developing and developed countries

Noting "there is a huge 'cancer divide' between rich and poor," with more than half of new cancer cases and almost two-thirds of all cancer deaths occurring in developing countries, this year's World Cancer Day theme, "Together It Is Possible," "calls on all individuals, organizations and governments to do their part to reduce premature deaths from cancers by 25 percent by 2025," Felicia Knaul, secretariat for the Global Task Force on Expanded Access to Cancer Care and Control in Developing Countries, and Jonathan Quick, president of Management Sciences for Health, write in a Huffington Post opinion piece.

7 Feb 2012

Cyclin D1 oncogene may promote chromosomal instability

A team of researchers at Jefferson's Kimmel Cancer Center (KCC) led by Richard G. Pestell, M.D., PhD., FACP, Director of the KCC and Chair of the Department of Cancer Biology, have shown in a study published online Feb. 6 in the Journal of Clinical Investigation that the oncogene cyclin D1 may promote a genetic breakdown known as chromosomal instability (CIN). CIN is a known, yet poorly understood culprit in tumor progression.

7 Feb 2012

How 'observation care' status can drive up patients' hospital bills

News outlets report that this kind of status is leading some Medicare beneficiaries to be surprised by the size of hospital bills because, ultimately, the services they received were not classified as inpatient care.

7 Feb 2012

Study may explain why women have higher rate of ACL injuries than men

Much orthopaedic research has been devoted to determining why women are far more susceptible to knee ligament injuries than men. According to a new study, the answer may lie in geometry - the length and shape of a patient's knee bone - more than gender.

7 Feb 2012

Viewpoints: Religious freedom and insurance coverage for contraception

In an election-year hothouse, the issue has quickly become caricatured as the Obama administration's "war on Catholics" versus the Republicans' "war on contraception." It is neither. The administration tried to strike a balance and simply failed. The First Amendment's guarantee of religious freedom deserves more weight than the administration allowed.

7 Feb 2012

Vitrolife fourth quarter sales increase 18% to SEK 95 million

Vitrolife AB: Fourth quarter - Sales increased by 19 percent in local currency. Sales were the highest ever for a single quarter and amounted to SEK 95 (81) million, corresponding to an increase of 18 percent in SEK.

7 Feb 2012

WHO disputes study's claims that global malaria deaths are double current estimates

The WHO has disputed a study published last week in the Lancet "that claims nearly twice as many people are dying of malaria than current estimates," VOA News reports.

7 Feb 2012

Inhibiting MET signaling in glioblastoma has major therapeutic value

A recent discovery by Van Andel Research Institute (VARI) scientists enables the prediction of patient sensitivity to proposed drug therapies for glioblastoma - the most common and most aggressive malignant brain tumor in humans.

7 Feb 2012

Supporting scientific evidence under PEPFAR to end AIDS

On Wednesday, several HIV experts spoke at a Capitol Hill briefing "supporting the U.S. President's Emergency Plan for AIDS Relief (PEPFAR) program's reliance on scientific evidence to drive its work to end AIDS," the Center for Global Health Policy's "Science Speaks" blog reports.

7 Feb 2012

Visual working memory not as specialized in the brain as visual encoding

Researchers have long known that specific parts of the brain activate when people view particular images. For example, a region called the fusiform face area turns on when the eyes glance at faces, and another region called the parahippocampal place area does the same when a person looks at scenes or buildings. However, it's been unknown whether such specialization also exists for visual working memory, a category of memory that allows the brain to temporarily store and manipulate visual information for immediate tasks.

7 Feb 2012

Sugar poses significant health risks, should be regulated like alcohol, U.S. researchers say

"Sugar poses enough health risks that it should be considered a controlled substance just like alcohol and tobacco, contend a team of researchers from the University of California, San Francisco (UCSF)," in an opinion piece called "The Toxic Truth About Sugar," published in the journal Nature on Wednesday, TIME's "Healthland" blog reports.

7 Feb 2012

Novel stem-cell technique to enhance bone growth

A research team led by UC Davis Health System scientists has developed a novel technique to enhance bone growth by using a molecule which, when injected into the bloodstream, directs the body's stem cells to travel to the surface of bones.

7 Feb 2012