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FDA denies AstraZeneca Citizen Petitions on SEROQUEL labeling

AstraZeneca today announced that on March 7, 2012, the Food and Drug Administration denied Citizen Petitions requesting that the FDA withhold finally approving any generic quetiapine product with labeling that omits certain hyperglycemia warning language that the FDA required AstraZeneca to include in the labeling for SEROQUEL (quetiapine fumarate) tablets and SEROQUEL XR (quetiapine fumarate) extended-release tablets.

12 Mar 2012

HSS summit: Current classification system for osteoarthritis is inadequate

A recent summit that brought together international multidisciplinary experts has provided a foundation for addressing what is the leading cause of disability in the United States: osteoarthritis.

12 Mar 2012

DeSyRe develops new design techniques for future Systems-on-Chips

For pacemakers and other implantable medical devices there are three key factors: extreme reliability, small size, and long longevity. In the EU project DeSyRe, researchers tackle these issues with a new approach: building a reliable system on unreliable components. Ioannis Sourdis, project leader, today explains the DeSyRe's approach in a tutorial on "Hardware and software design and verification for safety critical electronic systems" during the DATE 2012 conference in Dresden.

12 Mar 2012

ITQB, REQUIMTE convert solid antibiotic ampicilin into an ionic liquid form

In a daring move into the biomedical arena, ITQB chemists from the Molecular Thermodynamics Lab and collaborators from REQUIMTE have managed to convert the solid antibiotic ampicilin into an ionic liquid form, a method that may be extended to other pharmaceutical compounds with benefits for their administration. The work is now published in Medicinal Chemistry Communications.

12 Mar 2012

New insight into causes of childhood pneumonia

The scientific journal Clinical Infectious Diseases has released its March Special Supplement focusing entirely on the research design of and pilot data from the Pneumonia Etiology Research for Child Health (PERCH) Project, which seeks to identify the causes of pneumonia among the world's most vulnerable populations.

12 Mar 2012

PXR protein can protect against cardiovascular disease

Researchers from Queen Mary, University of London and the University of Surrey have found a protein inside blood vessels with an ability to protect the body from substances which cause cardiovascular disease.

12 Mar 2012

ICAP releases results from HPTN 064 Women's HIV Seroincidence Study

ICAP at Columbia University's Mailman School of Public Health is part of a network of research organizations that jointly released results, finding that HIV infection rates of black women living in certain parts of the U.S. are higher than previously estimated for black adolescent and women living in the U.S.

12 Mar 2012

Hospitals with infection control certification may have lower MRSA BSI rates

Hospitals whose infection prevention and control programs are led by a director who is board certified in infection prevention and control have significantly lower rates of methicillin-resistant Staphylococcus aureus (MRSA) bloodstream infections (BSI) than those that are not led by a certified professional, according to a new study published in the March issue of the American Journal of Infection Control, the official publication of APIC - the Association for Professionals in Infection Control and Epidemiology.

12 Mar 2012

Santorum, others say Romney won't be able to campaign against Obama's health law

As Mitt Romney moves closer to locking up the Republican presidential nomination, the questions about his ability to attack President Obama on healthcare are only getting louder. Conservatives have long been uneasy with Romney's record on healthcare.

12 Mar 2012

TGen to present new research about multiple myeloma at AzMN conference

The Translational Genomics Research Institute (TGen) will present new research about the blood-cell cancer known as multiple myeloma at a free public conference hosted by the Arizona Myeloma Network.

12 Mar 2012

Tranylcypromine shows promise against AML

A retinoid called all-trans retinoic acid (ATRA), which is a vitamin A-derivative, is already used successfully to treat a rare sub-type of acute myeloid leukemia (AML), however this drug has not been effective for the more common types of AMLs.

12 Mar 2012

New Burn Medical Education app for physicians, students

A newly released mobile app designed to educate medical students, physicians and health care workers around the globe on how to care for burn victims is one of a fast-growing number of medical apps being developed at Johns Hopkins Medicine.

12 Mar 2012

TSRI, OPKO Health to develop and commercialize SR 3306 for Parkinson's

OPKO Health, Inc. and The Scripps Research Institute today announced a global agreement for the development and commercialization of SR 3306, a novel compound discovered by scientists from the Florida campus of The Scripps Research Institute that blocks the destruction of brains cells in animal models of Parkinson's disease.

12 Mar 2012

AMGA honors Abbott with Distinguished Corporate Partner Award

The American Medical Group Association (AMGA) announced today that it will present the AMGA Distinguished Corporate Partner Award on March 10 to Abbott Laboratories at its 2012 Annual Conference, March 8-10 at the Manchester Grand Hyatt.

12 Mar 2012

First study to document potential effects of cancer on young children's development

Infants and toddlers who have been treated for cancer tend to reach certain developmental milestones later than do their healthy peers, say researchers at the National Institutes of Health and in Italy.

12 Mar 2012

UCSD now offer novel weight-loss surgery, gastric plication

Patients seeking a weight-loss surgery that does not require an implanted device or permanent change to their anatomy, have a new clinical trial option at UC San Diego Health System. Santiago Horgan, MD, chief of minimally invasive surgery, and his team, now offer gastric plication, a novel surgery that folds the stomach into a smaller, more compact size.

12 Mar 2012

HIPK2 regulator protein plays a crucial role in kidney fibrosis

Researchers from Mount Sinai School of Medicine have identified a regulator protein that plays a crucial role in kidney fibrosis, a condition that leads to kidney failure. Finding this regulator provides a new therapeutic target for the millions of Americans affected by kidney failure. The research is published in the March 11 issue of Nature Medicine.

12 Mar 2012

OSU researchers use carbon nanotubes to increase the speed of biological sensors

Researchers at Oregon State University have tapped into the extraordinary power of carbon "nanotubes" to increase the speed of biological sensors, a technology that might one day allow a doctor to routinely perform lab tests in minutes, speeding diagnosis and treatment while reducing costs.

12 Mar 2012

Women Democratic Senators to Boehner: 'Nix' vote on birth control coverage rule

The 12 senators wrote a letter to the House Speaker, asking him not to hold a vote on proposals to expand exemptions from the Obama administration's birth control coverage mandate.

12 Mar 2012

EMBO Molecular Medicine to join Wiley Open Access publishing program

Wiley-Blackwell, the scientific, technical, medical and scholarly publishing business of John Wiley & Sons, Inc., and EMBO today announced that EMBO Molecular Medicine will, as of March 2012, join the Wiley Open Access publishing program.

12 Mar 2012