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New path for individually tailored cancer therapy

The Institute of Translational Oncology (TRON) together with BioNTech AG today announced the publication of a joint paper in the international journal Cancer Research that describes a new path for individually tailored cancer therapy.

18 Jan 2012

With new poll showing low public approval, Congress returns to D.C.:'Doc fix,' tax cuts on agenda

The Associated Press reports that in order to prevent a 27 percent cut in Medicare payments to doctors, negotiators are trying to find $39 billion in cuts elsewhere in health spending. A deal could be reached faster than initially expected.

18 Jan 2012

Alnylam sues Tekmira over LNP-formulated siRNA molecules

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today that it has filed a patent infringement lawsuit against Tekmira Pharmaceuticals Corporation in the U.S. District Court of the District of Massachusetts.

18 Jan 2012

Research reports on effectiveness of Scriptaid in breast cancer cell lines

Although endocrine therapy for breast cancer has shown excellent results in controlling the disease, responsiveness to the therapy depends on whether or not there is expression of estrogen receptors in breast cancer cells. Research from the Sbarro Institute for Cancer Research and Molecular Medicine, a nonprofit cancer, cardiovascular and diabetes research center located in Philadelphia, PA, reports on the effectiveness of a new molecule, Scriptaid, that restores receptivity to endocrine therapy in breast cancer cell lines that had tested negative for the expression of estrogen receptors.

18 Jan 2012

Study compares adoptive T-cell therapy with drug-based cancer treatment

In the treatment of large tumors, how effective is adoptive T cell therapy in comparison to drug-based cancer treatment? To answer this question, Dr. Kathleen Anders and Professor Thomas Blankenstein of the Max Delbr-ck Center for Molecular Medicine (MDC) Berlin-Buch and researchers of the Beckman Research Institute of the City of Hope Cancer Center in Duarte, California, USA designed and carried out a study comparing the two methods. Based on a mouse cancer model, the researchers elucidated the mechanisms of the two different treatments.

18 Jan 2012

Teenagers more susceptible to addiction and depression

Teenagers are more susceptible to developing disorders like addiction and depression, according to a paper published by Pitt researchers Jan. 16 in the Proceedings of the National Academy of Sciences.

18 Jan 2012

Immobilization of one hand causes rearrangement of brain matter

What happens in the brain of right-handed people if their dominant hand is immobile for two weeks? This is the question addressed in the latest study led by Professor Lutz J-ncke and the Trauma Surgery Department at Zurich University Hospital.

18 Jan 2012

Food insecurity forces families to 'stretch' infant formula

Despite receiving supplemental food benefits, some families cannot afford enough infant formula and resort to the dangerous practice of formula "stretching" - watering down formula - to feed their babies, according to a Cincinnati Children's Hospital Medical Center study conducted at urban pediatric clinics.

18 Jan 2012

Scientists identify hepsin protein's role in breast cancer

Cancers rarely are deadly unless they evolve the ability to grow beyond the tissues in which they first arise. Normally, cells -- even early-stage tumor cells -- are tethered to scaffolding that helps to restrain any destructive tendencies. But scientists from the University of Helsinki, Finland, and from UCSF have identified a cleaver-wielding protein that frees some tumor cells, allowing them to further misbehave.

18 Jan 2012

Afghan President Karzai urges Taliban to allow polio vaccination teams into insurgent-controlled areas

Afghanistan President Hamid Karzai on Tuesday "urged the Taliban to allow teams conducting a polio vaccination campaign access to areas under their control" and "said that whoever hampers the medical workers 'is the enemy of our children's future,'" the Associated Press/Washington Post reports.

18 Jan 2012

Combination of tenotomy and PRP injections can treat tendon disorders

Many athletes know the frustration of being sidelined by tendon disorders, like Achilles tendinitis and tennis elbow. In recent years, doctors have begun treating overused tendons with regenerative therapies that jump-start the body's own healing process. One technique, a tenotomy, uses repeated needlesticks to break up scar tissue in the tendon, prompting the body's own cells to begin the rebuilding process.

18 Jan 2012

VeriTeQ acquires PositiveID's VeriChip and Health Link web-based PHR

VeriTeQ Acquisition Corporation, a marketer of implantable, radio frequency identification technologies for patient identification and sensor applications, announced today it has acquired the VeriChip implantable microchip and related technologies, and Health Link personal health record from PositiveID Corporation.

18 Jan 2012

Researchers develop simple process for synthesis of artemisinin

The most effective anti-malaria drug can now be produced inexpensively and in large quantities. This means that it will be possible to provide medication for the 225 million malaria patients in developing countries at an affordable price. Researchers at the Max Planck Institute of Colloids and Interfaces in Potsdam and the Freie Universit-t Berlin have developed a very simple process for the synthesis of artemisinin, the active ingredient that pharmaceutical companies could only obtain from plants up to now.

18 Jan 2012

Scientists develop new gallbladder endoscopy

For more than 100 years, the traditional treatment for the painful growths called gallstones has been removal of the gallbladder, or cholecystectomy. But a new device, patented in China, promises to make removing the entire organ unnecessary. A group of scientists from the Second People's Hospital of Panyu District and Central South University in China have developed an endoscope specially designed for locating and clearing out gallstones and other gallbladder lesions.

18 Jan 2012

Voraxaze receives FDA approval for treatment of toxic methotrexate levels

The U.S. Food and Drug Administration today approved Voraxaze (glucarpidase) to treat patients with toxic levels of methotrexate in their blood due to kidney failure.

18 Jan 2012

State roundup: State lawmakers, governors planning health legislation; Some Pa. kids losing Medicaid

Iowa House and Senate Republicans could support legislation requiring lawmakers to contribute to the cost of their state-provided health-care benefits, party leaders told the Des Moines Register's editorial board this morning. The health-care packages now offered by the state - in which most employees, including legislators, are not required to make contributions from their salaries - are "out of touch" with the plans available to average Iowans, ... House Speaker Kraig Paulsen, R-Hiawatha, said.

18 Jan 2012

Novelos initiates enrollment in HOT Phase 1b trial for advanced solid tumors

Novelos Therapeutics, Inc., a pharmaceutical company developing novel drugs for treatment and diagnosis of cancer, today announced that it has enrolled the first patient in a U.S. multi-center Phase 1b dose-escalation trial of its cancer-targeted molecular radiotherapeutic compound (131)I-CLR1404 (HOT) in cancer patients with advanced solid tumors.

18 Jan 2012