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$Merrimack commences MM-151 Phase 1 trial in refractory advanced solid tumors$

Merrimack commences MM-151 Phase 1 trial in refractory advanced solid tumors

Merrimack Pharmaceuticals, Inc. announced today that the first patient has been dosed in a Phase 1 clinical trial of MM-151, an oligoclonal therapeutic consisting of a mixture of three fully human monoclonal antibodies designed to bind to non-overlapping epitopes of the epidermal growth factor receptor.

11 Jan 2012

Arena agrees to sell 9,953,250 shares of common stock

Arena Pharmaceuticals, Inc. announced today that it has agreed to sell 9,953,250 shares of its common stock, at a price of $1.65775 per share, and approximately 9,953 shares of its Series D Convertible Preferred Stock, at a price of $1,657.75 per share, in a registered direct public offering to entities affiliated with Deerfield Management, a healthcare investment organization.

11 Jan 2012

HHS to spend nearly $1.8M to review research volunteer rules, fight STDs in Guatemala; DOJ asks related lawsuit to be dismissed

"Responding to U.S. experiments that infected Guatemalans with syphilis and gonorrhea in the 1940s, the Obama administration announced Tuesday that it will spend $1 million to study new rules for protecting medical research volunteers," and "an additional $775,000 will go to fighting sexually transmitted diseases in Guatemala," the Washington Post reports.

11 Jan 2012

DNA may be used to predict lifespan: Study

Researchers may soon be able to predict how long a person will live based on their genetics. This could result from the discovery by a University of Glasgow team in Scotland showing that telomere length on the ends of DNA in their genes in early-life predicts life spans.

11 Jan 2012

Breast fed babies versus formula fed babies: Who is crankier?

A new study finds that breastfed babies cry more, laugh less, and generally have “more challenging temperaments” than formula-fed infants. However such behavior is normal, and mothers should learn to cope with it rather than reach for the bottle, according to researchers.

11 Jan 2012

Regular aspirin may not be good for all: Study

Researchers suggest that healthy individuals who take aspirin to prevent a heart attack or stroke could be doing more harm than good. An analysis of more than 100,000 patients, published in Archives of Internal Medicine, concluded the risk of internal bleeding was too high. The UK-led study said only people with a history of heart problems or stroke should take the tablets. Experts however added that any decision should be made with a doctor.

11 Jan 2012

Weight gain and other metabolic side effects of bipolar and schizophrenia drugs may be countered

A new study suggests that young people who are diagnosed with bipolar disorder and schizophrenia may be spared the side-effects of taking medication with the right diet and exercise program.

11 Jan 2012

1 in 6 U.S. adults binge drinks: CDC report

According to a new CDC report around 1 in 6 U.S. adults binge drinks. This comes to 38 million people who overindulge. They do so an average of about four times a month, sometimes downing eight drinks at a sitting.

11 Jan 2012

DNA decoder – cheaper and faster

Life Technologies Corp. – a biotechnology company announced Tuesday that it has developed a machine to decode an individual's DNA in a day for just $1,000. The company said it was taking orders for the technology, which it expects to deliver in about a year. The Carlsbad, California, company said three major research institutions had already signed up for the $149,000 machine: the Baylor College of Medicine, the Yale School of Medicine and the Broad Institute of Cambridge, Massachusetts.

11 Jan 2012

Occasional marijuana use does not affect lung function: Study

A new study published in the Journal of the American Medical Association has shown that an occasional drag on marijuana does not appear to have long-term adverse effects on lung function.

11 Jan 2012

Researchers study fusion plasmas to understand fast dynamics of networks in the human brain

Fusion plasma researchers at the University of Warwick have teamed up with Cambridge neuroscientists to apply their expertise developed to study inaccessible fusion plasmas in order to significantly improve the understanding of the data obtained from non-invasive study of the fast dynamics of networks in the human brain.

11 Jan 2012

Researchers analyze microorganisms in human gut as a complex, integrated biological system

For the first time, researchers have analyzed the multitude of microorganisms residing in the human gut as a complex, integrated biological system, rather than a set of separate species. Their approach has revealed patterns that correspond with excess body weight.

11 Jan 2012

Potential human health risk from illegal wildlife trade

An article released today in PLoS ONE entitled, Zoonotic Viruses Associated with Illegally Imported Wildlife Products, from a collaborative study led by the U.S. Centers for Disease Control and Prevention (CDC), identified evidence of retroviruses and herpesviruses in illegally imported wildlife products confiscated at several U.S. international airports, including John F. Kennedy International Airport, George Bush Intercontinental-Houston and Atlanta Hartsfield-Jackson International.

11 Jan 2012

Findings support 'medical home' movement to improve health outcomes

Greater access to features of high-quality primary care -- comprehensiveness, patient-centeredness and extended office hours -- is associated with lower mortality, according to a new national UC Davis study. Published in the January-February issue of the Annals of Family Medicine, the research is the first to link the availability of three specific attributes of primary care with reduced risk of death.

11 Jan 2012

Special issue on self-determining environmental justice for native America

How best to ensure environmental justice for Native Americans in terms of policy, governance, and activism on tribal lands? The broad range of issues, challenges, and possibilities are explored in an insightful and thought-provoking special issue of Environmental Justice entitled "Environmental Justice in Native America." Environmental Justice is a peer-reviewed journal published by Mary Ann Liebert, Inc.

11 Jan 2012

New online publication on wound care

The rapidly advancing field of tissue injury and repair has an important new forum. Advances in Wound Care will report the latest research findings, innovative wound care strategies, industry product pipeline, and developments in biomaterials and skin and tissue regeneration to optimize patient outcomes.

11 Jan 2012

Collaborative behavioral management may be effective in reducing abuse among paroled marijuana users

A study from Rhode Island Hospital has found that collaborative behavioral management may be effective in reducing substance abuse among convicted marijuana users who are paroled. The findings have important implications for the management of a substantial proportion of the U.S. community correctional population.

11 Jan 2012

Saladax increases claims in immunoassay space to 15 patents

Saladax Biomedical, Inc., a privately held company developing and commercializing novel diagnostic assays to achieve the promise of personalized medicine for new and existing therapeutics, announced today that it has been issued six patents within the last 12 months, bringing the company's total to 15 issued U.S. patents, all of which contain broad claims in the immunoassay space.

11 Jan 2012

Children with chronic sleep problems may develop mental health disorders later in life

Children who have chronic sleep problems may be much more likely to develop mental health disorders as adolescents and adults, according to Candice Alfano, associate professor in clinical psychology at the University of Houston (UH) and director of the new Sleep and Anxiety Center for Kids (SACK).

11 Jan 2012

Study finds home-visit program could keep diabetes patients out of the hospital

A special Medicare program that stresses home health visits for patients with chronic diseases helped keep diabetes patients out of the hospital and may have lowered costs using time-honored prevention methods, researchers reported on Monday.

11 Jan 2012