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Bionomics, Ironwood partner to develop and commercialize novel anti-anxiety compound

Ironwood Pharmaceuticals, Inc. and Bionomics Limited today announced that they entered into a collaboration, research, and licensing agreement that will enable Ironwood to develop and commercialize Bionomics' investigational anti-anxiety compound BNC210 and other related compounds.

5 Jan 2012

FDA issues order prohibiting certain uses of cephalosporins in food-producing animals

The U.S. Food and Drug Administration today issued an order that prohibits certain uses of the cephalosporin class of antimicrobial drugs in cattle, swine, chickens and turkeys effective April 5, 2012.

5 Jan 2012

RGS9-2 gene plays a role in regulating body weight

Abraham Kovoor was studying a brain protein, called RGS9 2, that he had previously related to the involuntary, random and repetitive body movements that are side effects of drugs used to treat Parkinson's disease and schizophrenia.

5 Jan 2012

Antiestrogen supplements may reduce risk of melanoma in women with breast cancer

Women with breast cancer who take antiestrogen supplements may be decreasing their risk for melanoma, according to a study published in Cancer Prevention Research, a journal of the American Association for Cancer Research.

5 Jan 2012

Positive results from Alkermes ALKS 5461 phase 1/2 study on MDD

Alkermes plc today announced positive topline results from a phase 1/2 study of ALKS 5461, a novel drug compound for major depressive disorder (MDD) in patients who have an inadequate response to standard therapies for clinical depression.

5 Jan 2012

First study to elucidate how statins reduce activation of abnormal blood clotting

People with high cholesterol are at risk of heart attack and stroke because atherosclerotic plaques within their arteries can rupture triggering the formation of a blood clot called an occlusive thrombus that cuts off the blood supply to their heart or brain.

5 Jan 2012

Investigational HSV vaccine shows promise against two genital herpes diseases

An investigational vaccine protected some women against infection from one of the two types of herpes simplex viruses that cause genital herpes, according to findings in the New England Journal of Medicine.

5 Jan 2012

IHoP may play a critical role in type 1 diabetes

Researchers at Wake Forest Baptist Medical Center's Institute for Regenerative Medicine and colleagues have discovered a new protein that may play a critical role in how the human body regulates blood sugar levels.

5 Jan 2012

Free public lecture to look at role of stents in treating coronary artery diseases

State-of-the art treatments for patients with heart problems are the theme of a public lecture at the University of Greenwich this month. The lecture, which is free and open to all, will look at the role of stents in treating coronary artery diseases. A stent is a tiny, artificial tube which is placed in the coronary arteries that supply the heart: by keeping the arteries open, the stent combats the effects of reduced blood flow, such as blood clots.

5 Jan 2012

State roundup: Mass. insurance co-ops to launch; Fla. hospital commission ponders nonprofits

A federal appeals court will review a judge's decision to temporarily block the state of Texas from enforcing a law requiring doctors to show sonograms to patients and describe the images before an abortion. In August, U.S. District Judge Sam Sparks in Austin, Texas, ruled that several provisions of the law violated the free-speech rights of abortion-performing doctors.

5 Jan 2012

Lithocholic acid can kill several types of cancer cells

Lithocholic acid (LCA), naturally produced in the liver during digestion, has been seriously underestimated. A study published in the journal Oncotarget shows that LCA can kill several types of cancer cells, such as those found in some brain tumors and breast cancer.

5 Jan 2012

Study reveals factors associated with prevention, control of HIV infection

New vaccine research in monkeys suggests that scientists are homing in on the critical ingredients of a protective HIV vaccine and identifies new HIV vaccine candidates to test in human clinical trials.

5 Jan 2012

Positive preliminary results from Alnylam's Phase I ALN-PCS trial on severe hypercholesterolemia

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today the achievement of positive preliminary results from its ongoing clinical trial of ALN-PCS, an RNAi therapeutic targeting PCSK9 for the treatment of severe hypercholesterolemia.

5 Jan 2012

NGP receives investment from Abbott to develop NGP 555 for AD

NeuroGenetic Pharmaceuticals, Inc. (NGP), a privately held biopharmaceutical company focused on Alzheimer's disease (AD) therapeutics, has received an investment from Abbott Biotech Ventures.

5 Jan 2012

New FAO head says agency will increase support to countries experiencing prolonged food crises

The new head of the U.N. Food and Agriculture Organization (FAO), Director-General José Graziano da Silva, began work on January 1, "pledging on Tuesday to increase the agency's support to poor countries experiencing prolonged food crises," the U.N. News Centre reports.

5 Jan 2012

Rilonacept appears safe and well-tolerated in patients with gout

A phase II clinical trial found that rilonacept, an inhibitor of the protein interleukin-1 (IL-1), significantly reduced acute gout flares that occur when initiating uric acid-lowering therapy. Results of the trial—the first placebo-controlled study investigating IL-1 targeted therapy in prevention of gout flares—show rilonacept to be generally well tolerated with no serious infections or treatment-related serious adverse events reported.

5 Jan 2012

New algorithm could help GPs identify women at risk of early ovarian cancer

The lives of hundreds of women could be saved every year, thanks to a simple online calculator that could help GPs identify women most at risk of having ovarian cancer at a much earlier stage.

5 Jan 2012

Weight loss surgery can improve blood sugar control in diabetes patients

Weight loss surgery is not a cure for type 2 diabetes, but it can improve blood sugar control, according to a new study published in the British Journal of Surgery. Whereas some previous studies have claimed that up to 80 per cent of diabetes patients have been cured following gastric bypass surgery, researchers at Imperial College London found that only 41 per cent of patients achieve remission using more stringent criteria.

5 Jan 2012

Arrowhead receives FDA IND approval for Adipotide obesity drug

Arrowhead Research Corporation, a nanomedicine company with development programs in oncology and obesity, today announced that the Investigational New Drug Application (IND) for its first obesity drug candidate, Adipotide, was accepted by the U.S. Food and Drug Administration allowing the initiation of a clinical trial to test the safety of the compound.

5 Jan 2012

Viewpoints: Sebelius on 'essential benefits'; WSJ columnist on Democrats' 'Mediscare' argument - is it a lie?

Insurance needs and health systems vary state to state, and experience tells us that the best way forward is not to mandate a one-size-fits-all answer. Instead, our approach gives states the flexibility to take their own paths, while ensuring they all end up in the best place possible: with an Affordable Insurance Exchange that offers access to comprehensive, quality, affordable health insurance to small business owners and individuals who currently have few good choices in an expensive and broken market.

5 Jan 2012

Medical News

Bionomics, Ironwood partner to develop and commercialize novel anti-anxiety compound

FDA issues order prohibiting certain uses of cephalosporins in food-producing animals

RGS9-2 gene plays a role in regulating body weight

Antiestrogen supplements may reduce risk of melanoma in women with breast cancer

Positive results from Alkermes ALKS 5461 phase 1/2 study on MDD

First study to elucidate how statins reduce activation of abnormal blood clotting

Investigational HSV vaccine shows promise against two genital herpes diseases

IHoP may play a critical role in type 1 diabetes

Free public lecture to look at role of stents in treating coronary artery diseases

State roundup: Mass. insurance co-ops to launch; Fla. hospital commission ponders nonprofits

Lithocholic acid can kill several types of cancer cells

Study reveals factors associated with prevention, control of HIV infection

Positive preliminary results from Alnylam's Phase I ALN-PCS trial on severe hypercholesterolemia

NGP receives investment from Abbott to develop NGP 555 for AD

New FAO head says agency will increase support to countries experiencing prolonged food crises

Rilonacept appears safe and well-tolerated in patients with gout

New algorithm could help GPs identify women at risk of early ovarian cancer

Weight loss surgery can improve blood sugar control in diabetes patients

Arrowhead receives FDA IND approval for Adipotide obesity drug

Viewpoints: Sebelius on 'essential benefits'; WSJ columnist on Democrats' 'Mediscare' argument - is it a lie?

Advancing Menopause Care: Non-Hormonal Treatments for Vasomotor Symptoms

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

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