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Y chromosome may be the link that passes heart disease risk from father to son

The study, published in The Lancet, focused on genetic markers on the Y chromosome — which is present only in male DNA (women have two X chromosomes) — and found that men with a certain genetic variant were 50% more likely to have coronary artery disease than those without it. The increased risk was independent of other contributors to heart disease such as age, weight, high cholesterol, high blood pressure and smoking.

12 Feb 2012

FDA lays guidelines for “biosimilar” biotech drugs

The proposed rules, issued on Thursday, require studies showing that the generic copies are “highly similar” to the originals, but there are several ways that might be proven. Because of their complexity, generic copies of biotech drugs - first introduced in the 1980s - are known as “biosimilars.” The worldwide market for copies of biotech medicines will grow to $3.7 billion by 2015, from just $243 million in 2010, as more than 30 branded biologics with sales of $51 billion lose patent exclusivity, according to market analysis firm Datamonitor.

12 Feb 2012

Deep brain stimulation helps improve memory and cognitive skills in epilepsy patients

Researchers have found that deep brain stimulation by sending in electric shocks to a part of the brain that plays a key role in memory improved people's ability to learn. This could raise hope for patients of Alzheimer’s.

12 Feb 2012

Preterm C-section could raise risk of breathing difficulties: Study

Cesarean sections are often performed when a baby is going to be born early. Labor may also be induced when a woman's water breaks too early in the pregnancy. However, two new studies suggest that these common practices may, in fact, not benefit babies. The two new studies were presented Thursday at the annual meeting of the Society for Maternal-Fetal Medicine.

12 Feb 2012

Tai chi could benefit Parkinson’s disease patients

A new study found that a six-month program of Tai Chi exercises helped people with various stages of Parkinson's disease improve stability, their ability to walk and reduced the frequency of falls.

12 Feb 2012

Cancer drug bexarotene effective in mouse model of Alzheimer’s

Case Western Reserve University School of Medicine neuroscientist Gary Landreth and colleagues reported Thursday that the drug - bexarotene quickly cleared away beta-amyloid plaque, believed to cause the cognitive deficits of Alzheimer's disease, from the brains of genetically engineered mice.

12 Feb 2012

Human 'shock absorbers' discovered

An international team of scientists, led by the University of Sydney, has found the molecular structure in the body which functions as our “shock absorber”. The discovery of the previously unknown part of the molecule will be applied to the researchers’ work on designing improved versions of a human blood vessel and on repairing skin damage, including burns.

12 Feb 2012

Preliminary results from Soligenix SGX201 Phase 1/2 trial on acute radiation enteritis

Soligenix, Inc., a development stage biopharmaceutical company, announced preliminary results today from a Phase 1/2 clinical trial evaluating SGX201, a time-release formulation of oral beclomethasone 17,21-dipropionate (oral BDP), for the prevention of acute radiation enteritis.

10 Feb 2012

Taro fourth quarter net sales increase 44.3% to $148.1 million

Taro Pharmaceutical Industries Ltd. today provided unaudited financial results for the quarter and full year ended December 31, 2011.

10 Feb 2012

Bupivacaine may effectively manage pain after total knee replacement

Researchers at the Rothman Institute at Jefferson have shown that local anesthesia delivered through a catheter in the joint, intraarticularly, may be more beneficial than traditional opioids such as morphine and Oxycontin for pain management following total knee replacement surgery.

10 Feb 2012

Exelixis prices underwritten public offering of common stock

Exelixis, Inc. today announced the pricing of its underwritten public offering of 11,000,000 shares of newly issued common stock at a price to the public of $5.50 per share.

10 Feb 2012

Some high-profile Catholic Democrats are criticizing HHS rule

Sens. Robert Casey and Joe Manchin, Rep. John Larson and Obama adviser Tim Kaine are breaking with the White House on the contraception controversy.

10 Feb 2012

TKR surgeries have more than doubled over the past decade

New research presented at the 2012 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS) found that more than 4.5 million Americans are living with a total knee replacement (TKR), as the number of TKR surgeries has more than doubled over the past decade, with the sharpest rise among younger patients. Osteoarthritis continues to be the primary reason for TKR.

10 Feb 2012

Study investigates how cytokine IFN-λ release is regulated

In new research appearing in this month's issue of the journal Nature Immunology, Roy Curtiss, director of the Center for Infectious Diseases and Vaccinology at the Biodesign Institute at Arizona State University, along with international collaborators, investigates the coordination of a particular type of immune response, involving the release of of IFN-λ- a cell-signaling protein molecule known as a cytokine.

10 Feb 2012

Study reveals racial disparities in renal transplant access

A new study published in the American Journal of Transplantation reveals that racial disparities exist in both the early and late steps in access to kidney transplantation. This study is part of the February special themed issue of the journal on racial disparity.

10 Feb 2012

Scientists discover ferocity of immune system after viral infection

A scientific team led by researchers at the University of Geneva (UNIGE) and the Charité Berlin Medical University has made a completely unprecedented discovery showing how much our immune system is provoked into action when confronted by viral intruders.

10 Feb 2012

Two studies on shoulder instability in military population

Two studies on shoulder instability in a military population were presented today by U.S. Army sports medicine surgeons at the American Academy of Orthopaedic Surgeons' annual meeting.

10 Feb 2012

Medicaid changes eyed in Georgia, California and Connecticut

State officials are creating two task forces to gather input on a consulting firm's report on the future of Georgia's Medicaid and PeachCare programs. One task force will involve medical provider groups, including representatives of hospital and physician organizations. The second grouping will review the Navigant report's recommendation to revamp services for the "aged, blind and disabled" populations.

10 Feb 2012