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GSK, ProteoTech enter R&D agreement to develop new Parkinson's therapeutics

ProteoTech, Inc., a privately held biotechnology company, has entered into a drug development agreement with GlaxoSmithKline (China) R&D Company Limited (GSK) to collaborate on ProteoTech's small molecule technology platform against misfolded proteins to specifically advance work on its alpha-synuclein therapeutic program for the treatment of Parkinson's disease and other synucleinopathies.

21 Dec 2011

Mother's milk for healthy growth

A PhD project from LIFE - the Faculty of Life Sciences at the University of Copenhagen has shown that breastfed children follow a different growth pattern than non-breastfed children. Breastfeeding lowers the levels of the growth hormones IGF-I and insulin in the blood, which means that growth is slightly slower. This is believed to reduce the risk of overweight and diabetes later in life.

21 Dec 2011

Tips for people to lose weight, quit smoking and manage stress this New Year

As the New Year rolls in, many people will be looking to better themselves by resolving to lose weight, quit smoking and manage stress. Sticking to resolutions for more than a few weeks, however, is a lofty task that takes a great deal of motivation and even lifestyle changes.

21 Dec 2011

Study examines changes in RHR with risk of death from ischemic heart disease

In a study that enrolled nearly 30,000 apparently healthy men and women, those who had an increase in their resting heart rate over a 10-year period had an increased risk of death from all causes and from ischemic heart disease, according to a study in the December 21 issue of JAMA.

21 Dec 2011

Anxious individuals are less sensitive to their environments: Study

Anxious people have long been classified as "hypersensitive" - they're thought to be more fearful and feel threatened more easily than their counterparts. But new research from Tel Aviv University shows that the anxious may not be hypersensitive at all - in fact, they may not be sensitive enough.

21 Dec 2011

AUA, AIUM develop practice guideline for ultrasound imaging in urology

The American Institute of Ultrasound in Medicine (AIUM) and American Urological Association (AUA) are pleased to announce the collaborative development of the Practice Guideline for the Performance of an Ultrasound Examination in the Practice of Urology.

21 Dec 2011

CWRU receives NIDDK grant to study role of innate immunity in IBD

Investigators at Case Western Reserve University School of Medicine received a $6.75 million Program Project Grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) to study the role of innate immunity in inflammatory bowel disease.

21 Dec 2011

Fate of India's Food Security Bill unknown; Analysts say it may harm country's economy

"Though approved by the Cabinet Sunday, the fate of the much-anticipated Food Security Bill, which will guarantee cheap food for India's masses, is far from sealed," the Wall Street Journal's "India Real Time" blog reports, noting that the "bill is to be tabled in Parliament this week."

21 Dec 2011

Study assesses evidence of immunosuppression in sepsis

An analysis of lung and spleen tissue from patients who died of sepsis revealed certain biochemical, cellular and histological findings that were consistent with immunosuppression, according to a study in the December 21 issue of JAMA.

21 Dec 2011

UCB initiates EXXELERATE study in rheumatoid arthritis

UCB today announced the start of the EXXELERATE study which will evaluate the short- and long-term efficacy of Cimzia (certolizumab pegol) plus methotrexate (MTX) compared with that of Humira(adalimumab) plus MTX in the treatment of moderate to severe rheumatoid arthritis (RA). The start of this study confirms previously announced plans.

21 Dec 2011

Survey: 40% of police officers have sleep disorders

A survey of police officers indicated that about 40 percent have a sleep disorder, which was associated with an increased risk of adverse health, safety and performance outcomes, according to a study in the December 21 issue of JAMA.

21 Dec 2011

Heart-related deaths, other emergencies peak in holiday season

Steven Polevoi, MD, has seen it all. During his 23-year career, the medical director of the UCSF Emergency Department has done everything from treat traumatic injuries to deliver babies. While medical emergencies occur throughout the year, Polevoi sees the winter season and its related overindulgence as a pivotal time for preventing emergencies by listening to our bodies.

21 Dec 2011

Obesity doubles risk of recurrence and death after esophageal cancer surgery

Obesity doubles the risk of cancer recurrence and cancer-related death in patients with esophageal cancer who have been treated with surgery, researchers at Mayo Clinic found.

21 Dec 2011

Scientists create functional model of native extracellular matrix

Scientists at the National Physical Laboratory (NPL) have created a functional model of the native extracellular matrix that provides structural support to cells to aid growth and proliferation. The model could lead to advances in regenerative medicine.

21 Dec 2011

Mazor Robotics announces purchase agreement with NSH Michigan

Mazor Robotics Ltd, the leader in innovative surgical robots and complementary products for spine surgery, announced a purchase agreement with NSH Michigan, Inc.

21 Dec 2011

FDA accepts Pfizer's tofacitinib NDA for review

Pfizer Inc. announced today that the U.S. Food and Drug Administration (FDA) has accepted for review the New Drug Application (NDA) for tofacitinib (development code CP-690,550), an investigational novel, oral JAK inhibitor being studied for the treatment of adult patients with moderately to severely active rheumatoid arthritis.

21 Dec 2011

University of Oxford scientists develop new candidate malaria vaccine

A new candidate malaria vaccine with the potential to neutralise all strains of the most deadly species of malaria parasite has been developed by a team led by scientists at the University of Oxford.

21 Dec 2011

Guardian examines efforts to bring therapeutic food production into developing countries

The Guardian examines how ready-to-use therapeutic foods (RUTFs) -- "small packets of a sticky, peanut butter-like paste, fortified with minerals and vitamins, that can reverse severe malnutrition within six weeks" -- "have revolutionized famine relief in Africa," and asks whether these products could be produced in the countries in which they are being distributed.

21 Dec 2011

Handheld near-infrared imaging device enables quick detection of hematomas

When accidents that involve traumatic brain injuries occur, a speedy diagnosis followed by the proper treatment can mean the difference between life and death. A research team, led by Jason D. Riley in the Section on Analytical and Functional Biophotonics at the U.S. National Institutes of Health, has created a handheld device capable of quickly detecting brain injuries such as hematomas, which occur when blood vessels become damaged and blood seeps out into surrounding tissues where it can cause significant and dangerous swelling.

21 Dec 2011