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Clinical Cancer Research publishes results of Aduro's ANZ-100 and CRS-207 Phase 1 studies

Aduro BioTech, Inc. is pleased to announce the publication of two therapeutic cancer vaccine Phase 1 studies in Clinical Cancer Research. In the article, which was featured as one of the highlights of the issue, Dr. Dung Le et al. reported that intravenous administration of ANZ-100 and CRS-207 was well tolerated in subjects with advanced, treatment-refractory cancers.

7 Feb 2012

Ultrasound makes arthritis evaluation and treatment quicker and more accurate

Ultrasound is transforming the way arthritis is diagnosed and treated, making evaluation and treatment quicker and more accurate. The new approach is dubbed fast arthritis sonographic evaluation and treatment, or FAST, by rheumatologists at NewYork-Presbyterian Hospital/Columbia University Medical Center who are leading its development.

7 Feb 2012

Antiretroviral therapy does not increase severity of psychiatric disorders

A study of more than 300 children and adolescents with human immunodeficiency virus (HIV) revealed no association between specific antiretroviral therapy and the severity of psychiatric disorders.

7 Feb 2012

NYU Langone experts to present at American Academy of Orthopaedic Surgeons annual meeting

Experts from the Department of Orthopaedic Surgery at NYU Langone Medical Center will present their latest research and clinical findings on diseases of the muscle, tendon, bone and joint at the annual meeting of the American Academy of Orthopaedic Surgeons (AAOS), February 7-11 in San Francisco, California.

7 Feb 2012

ECNP expresses deep concern at withdrawal by AstraZeneca from neuroscience drug research

The European College of Neuropsychopharmacology expresses its deep concern at the recently announced withdrawal by AstraZeneca from neuroscience drug research. AstraZeneca's pull-out is especially disturbing given that it follows a series of similar withdrawals in the last two years by major pharmaceutical companies. There is a growing sense that neuroscience in Europe is now facing a severe crisis.

7 Feb 2012

BD first quarter revenues increase 2.5% to $1.888 billion

BD, a leading global medical technology company, today reported quarterly revenues of $1.888 billion for the first fiscal quarter ended December 31, 2011, representing an increase of 2.5 percent from the prior-year period, or 2.4 percent on a foreign currency-neutral basis.

From BD (Becton, Dickinson and Company) 7 Feb 2012

Three new targeted drugs can lead to fatal cancer complications

Treatment with three relatively new "targeted" cancer drugs has been linked to a slightly elevated chance of fatal side effects, according to a new analysis led by scientists at Dana-Farber Cancer Institute. They added that the risk remains low, but should be taken into account by physicians and patients.

7 Feb 2012

ED can lead to potential cardiovascular disease in men

More than 12 million men have type 2 diabetes and that number is growing at an alarming rate. A little talked about complication of this disease is erectile dysfunction (ED), which can lead to an even more serious condition.

7 Feb 2012

Proactive test-and-treat case-detection strategy can combat malaria

As researchers work to eliminate malaria worldwide, new strategies are needed to find and treat individuals who have malaria, but show no signs of the disease. The prevalence of asymptomatic or minimally symptomatic malaria can be as high as 35 percent in populations with malaria and these asymptomatic individuals can serve as a reservoir for spreading malaria even in areas where disease transmission has declined.

7 Feb 2012

Merck completes two suvorexant Phase III trials on insomnia

Merck, known as MSD outside the United States and Canada, today provided an update on the development program for suvorexant, the company's investigational orexin receptor antagonist, which, if approved, will be a new mechanism for the treatment of insomnia.

7 Feb 2012

Ovid and LWW journals Technical Services team earns BenchmarkPortal certification

Wolters Kluwer Health is pleased to announce that its Ovid and LWW journals Technical Services team received certification as a Center of Excellence by BenchmarkPortal in collaboration the Center for Customer-Driven Quality, founded at Purdue University. Only 10% of companies that submit data under BenchmarkPortal's program are awarded a "Certification of Excellence."

7 Feb 2012

Women with higher mammographic density more likely to develop breast cancer

A new study analyses the influence that certain birth and infancy characteristics have on mammographic density - an important indicator of breast cancer risk. The results reveal that women born to mothers aged over 39 years and women who were taller and thinner than the average girl prior to puberty have a higher breast density. This brings with it an increased risk of developing breast cancer.

7 Feb 2012

State roundup: Legislatures, govs juggling costs and health programs

Medicaid spending is a matter of urgency almost everywhere in the country right now, but in few places is the urgency as palpable as it is here, where the governor refers to the federal-state health insurance program for the poor as "welfare," says it's necessary to eliminate coverage for 65,000 adults, and wants to stop paying room and board for some 2,000 elders who live in group homes. All these ideas are part of Republican Governor Paul LePage's plan to close a $220 million hole in the state's biennial Medicaid budget.

7 Feb 2012

TGen to host Pediatric Cancer Translational Genomics in Scottsdale

The Translational Genomics Research Institute (TGen) will host Pediatric Cancer Translational Genomics Feb. 6-8 at the Hotel Valley Ho in Scottsdale, bringing together more than 150 leading pediatric cancer researchers, clinicians and foundations to promote the exchange of information and ideas for advancing pediatric cancer research and treatment.

7 Feb 2012

U.N. supporting yellow fever vaccination campaigns in Cameroon, Ghana

Following an outbreak of the mosquito-borne yellow fever virus in Cameroon that has infected at least 23 people and killed at least seven people, U.N. and local officials are working to vaccinate "1.2 million people considered at high risk of contracting yellow fever, which has no cure," the U.N. News Centre reports.

7 Feb 2012

LE strips can rapidly diagnose periprosthetic joint infection

Rothman Institute at Jefferson joint researchers continue to seek better ways to diagnose and subsequently treat periprosthetic joint infection (PJI) in patients following total joint arthroplasty. Their latest research shows leukocyte esterase reagent (LE) strips, common in diagnosing urinary tract infections, can also have a role in rapid diagnosis of PJI.

7 Feb 2012

Closing the 'cancer divide' between developing and developed countries

Noting "there is a huge 'cancer divide' between rich and poor," with more than half of new cancer cases and almost two-thirds of all cancer deaths occurring in developing countries, this year's World Cancer Day theme, "Together It Is Possible," "calls on all individuals, organizations and governments to do their part to reduce premature deaths from cancers by 25 percent by 2025," Felicia Knaul, secretariat for the Global Task Force on Expanded Access to Cancer Care and Control in Developing Countries, and Jonathan Quick, president of Management Sciences for Health, write in a Huffington Post opinion piece.

7 Feb 2012

Cyclin D1 oncogene may promote chromosomal instability

A team of researchers at Jefferson's Kimmel Cancer Center (KCC) led by Richard G. Pestell, M.D., PhD., FACP, Director of the KCC and Chair of the Department of Cancer Biology, have shown in a study published online Feb. 6 in the Journal of Clinical Investigation that the oncogene cyclin D1 may promote a genetic breakdown known as chromosomal instability (CIN). CIN is a known, yet poorly understood culprit in tumor progression.

7 Feb 2012

How 'observation care' status can drive up patients' hospital bills

News outlets report that this kind of status is leading some Medicare beneficiaries to be surprised by the size of hospital bills because, ultimately, the services they received were not classified as inpatient care.

7 Feb 2012

Study may explain why women have higher rate of ACL injuries than men

Much orthopaedic research has been devoted to determining why women are far more susceptible to knee ligament injuries than men. According to a new study, the answer may lie in geometry - the length and shape of a patient's knee bone - more than gender.

7 Feb 2012