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High gut flora protects children against allergies

High diversity and a variety of bacteria in the gut protect children against allergies as opposed to some individual bacterial genera. These are the findings of a comprehensive study of intestinal microflora (gut flora) in allergic and healthy children, which was conducted at Linköping University in Sweden.

9 Dec 2011

Nurses report symptoms of burnout, job dissatisfaction

Nurses working in hospitals around the world are reporting they are burned out and dissatisfied with their jobs, reported researchers at the University of Pennsylvania School of Nursing's Center for Health Outcomes and Policy Research in a study of 100,000 nurses in nine countries.

9 Dec 2011

ACEP Emergency Ultrasound Guidelines receive AIUM recognition

In keeping with the American Institute of Ultrasound in Medicine's (AIUM) overarching mission of advancing the safe and effective use of ultrasound in medicine through education, research and development of guidelines, the AIUM recognizes the American College of Emergency Physicians (ACEP) Policy Statement Emergency Ultrasound Guidelines as meeting the qualifications for performing ultrasound in the emergency setting.

9 Dec 2011

Forbes interviews Sarah Brown about her work in maternal, child health advocacy

Sarah Brown, international advocate for global maternal and newborn health and wife of former British Prime Minister Gordon Brown, answers questions about her work from Forbes contributor Rahim Kanani in this interview excerpt.

9 Dec 2011

Positive results from Metabolex arhalofenate plus febuxostat study on hyperuricemia, gout

Metabolex announced positive results from its clinical study of arhalofenate in combination with febuxostat. A key goal in the treatment of gout is to address the patient's underlying hyperuricemia by treatment with drugs that lower serum uric acid.

9 Dec 2011

USPTO issues Diabetes Patent to Omni Bio

Omni Bio Pharmaceutical, Inc. today announced that U.S. Patent No. 8,071,551, entitled "METHODS AND COMPOSITIONS FOR TREATING DIABETES," was issued by the United States Patent and Trademark Office on December 6, 2011. The Diabetes Patent expires in May 2022.

9 Dec 2011

Pharmacyclics, Janssen partner to develop and market PCI-32765 anti-cancer compound

Janssen Biotech, Inc., one of the Janssen Pharmaceutical Companies of Johnson & Johnson, announced today that it has executed an agreement with Pharmacyclics, Inc. to jointly develop and market the anti-cancer compound, PCI-32765.

9 Dec 2011

FDA committee votes against CardioMEMS' Champion Heart Failure Monitoring System

CardioMEMS announced today that the U.S. Food and Drug Administration's (FDA) Circulatory Systems Devices advisory panel voted against the Champion Heart Failure Monitoring System, the first wireless, permanently implantable device that allows cardiologists to monitor heart failure patients from their homes.

9 Dec 2011

Viewpoints: Politics overtakes Plan B; Gingrich's entitlement plans; Cheeseburgers and death

Once again, the politics of birth control have trumped science and sound public policy. On Wednesday, the Obama administration overruled a carefully reasoned decision by the Food and Drug Administration to make the so-called morning-after pill available without prescription to adolescent girls below the age of 17.

9 Dec 2011

Scientists discover mechanism that controls 'fat switch' in the body

Scientists at Warwick Medical School have made an important discovery about the mechanism controlling the body's 'fat switch', shedding new light on our understanding of how proteins regulate appetite control and insulin secretion.

9 Dec 2011

Toxins in Danish mushroom are effective against cancer cells

Researchers at the University of Copenhagen have explored the active principles of a Danish mushroom and found that some of the substances it contains are particularly toxic towards cancer cells. The goal is to synthesise and refine substances in the mushroom that may be useful in future drug development.

9 Dec 2011

Dietary fibers from brown algae help people lose more weight

A new research project conducted at the Faculty of Life Sciences (LIFE), University of Copenhagen, shows that dietary fibres from brown algae boost the sensation of satiety, thereby making people eat less and lose more weight.

9 Dec 2011

Galectin Therapeutics to initiate GM-CT-01 Phase 1/2 combination study in advanced MM

Galectin Therapeutics, the Cancer Centre at the Cliniques universitaires Saint-Luc and the Ludwig Institute for Cancer Research (LICR) announced today that they will initiate a Phase 1/2 safety and efficacy trial testing a novel treatment combination in patients with advanced metastatic melanoma.

9 Dec 2011

Toyota's lean approach might be beneficial to medical procedures

Japanese vehicle manufacturer, Toyota, is well-known for developing the principles of so-called "lean manufacturing". Research published in the International Journal of Technology Management suggests that the lean approach might also be beneficial to medical procedures, making hospitals more efficient and cut waiting lists.

9 Dec 2011

ChemoCentryx commences CCX140 Phase II trial in diabetic nephropathy

ChemoCentryx, Inc. today announced the initiation of a Phase II clinical trial for CCX140, an orally-administered small molecule for the treatment of diabetic kidney disease.

9 Dec 2011

FDA approves Boston Scientific's Infinion 16 Lead for chronic pain management

Boston Scientific Corporation announces U.S. Food and Drug Administration (FDA) approval of the Infinion 16 Percutaneous Lead for its Precision Plus Spinal Cord Stimulator (SCS) System, the first rechargeable SCS device for chronic pain management.

9 Dec 2011

Breakthrough advance in tackling dangerous 'bad' cholesterol in the body

Scientists from the University of Leicester and University of California Los Angeles (UCLA) have announced a breakthrough advance in tackling dangerous 'bad' cholesterol in the body.

9 Dec 2011

Global health R&D funding from wealthy nations fell 6% in 2010, annual G-FINDER report finds

"A group that tracks funding for neglected diseases released its fourth annual report Wednesday, showing for the first time since 2007 a decrease in government and public spending in global health research and development," the Center for Global Health Policy's "Science Speaks" blog reports.

8 Dec 2011

FDA advisory panel OKs anemia drug peginesatide

Once approved by the FDA, the once-monthly injection could capture a share of the $3 billion U.S. market for anemia drugs used for kidney dialysis patients, currently dominated by Amgen Inc's blockbuster Epogen. Affymax, which developed the drug with partner Takeda Pharmaceutical Co Ltd, is also expected to price its product below Epogen.

8 Dec 2011

Working night shifts may raise risk of diabetes: Study

About 26% percent of the American workforce, including health-care workers and sanitation staff, need to work night shifts. Earlier research has shown that regular night shifts may disrupt the circadian rhythm, raising the risk of heart disease, obesity, ulcers and even depression.

8 Dec 2011