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Researchers map every apparent physical interaction of HIV virus with human cells

In perhaps the most comprehensive survey of the inner workings of HIV, an international team of scientists led by researchers at the University of California, San Francisco has mapped every apparent physical interaction the virus makes with components of the human cells it infects—work that may reveal new ways to design future HIV/AIDS drugs.

22 Dec 2011

Report outlines steps for transition of PEPFAR service delivery to S. African government

The Center for Strategic & International Studies' "Smart Global Health" blog highlights a report called "Terra Nova: How to Achieve a Successful PEPFAR Transition in South Africa," writing, "The United States and South Africa are negotiating a complex, multi-year handoff that will shift financial and managerial responsibilities for HIV/AIDS to the South African government and move the United States away from direct service delivery and into technical assistance.

22 Dec 2011

Scientists discover N-cadherin as promising therapeutic target for pancreatic cancer

Often, and without much warning, pancreatic cancer cells slip through the endothelial cells, head into the blood and out to other parts of the body to metastasize, making it one of the deadliest and hardest to treat cancers today.

22 Dec 2011

Researchers discover how c-MYC facilitates tumor growth

Cancer cells are essentially immortal. The acquisition of an unlimited capacity to divide - the process of immortalization - is a central event in the genesis of tumors. Normally, cells are subject to stringent mechanisms which control their proliferation. Together these ensure that pre-malignant cells are induced to enter a senescent, non-dividing state or to undergo apoptosis, i.e. commit suicide.

22 Dec 2011

Autism Speaks announces 47 new ASD research grants

Autism Speaks, the world's largest autism science and advocacy organization, today announced the awarding of 47 new research grants totaling $13,242,279 in funding over the next three years.

22 Dec 2011

Study hopes to explain premature births and failed inductions of labour

New research hopes to explain premature births and failed inductions of labour. The study by academics at the University of Bristol suggests a new mechanism by which the level of myosin phosphorylation is regulated in the pregnant uterus.

22 Dec 2011

Government, humanitarian agencies respond to flooding in Philippines, warn of disease threat

"Philippine authorities are warning of the spread of diseases in cramped evacuation centers, days after flash floods hit the southern Philippines and claimed more than a thousand lives," ABC/Asia Pacific News reports, noting that flooding also has affected the country's northern provinces, displacing at least 50,000 people.

22 Dec 2011

JAMA commentary argues that vitamin therapy still plays a role in reducing stroke

A commentary by Dr. David Spence of The University of Western Ontario and Dr. Meir Stampfer of the Harvard School of Public Health in today's Journal of the American Medical Association (JAMA) argues that vitamin therapy still has a role to play in reducing stroke.

22 Dec 2011

TriVascular treats first Canadian patients with Ovation Abdominal Stent Graft

TriVascular, Inc. of Santa Rosa, California, announced today the first Canadian patients treated with its Ovation Abdominal Stent Graft. The innovative, ultra low profile (14F OD) system is designed to expand the patient population suitable for endovascular aortic repair (EVAR) by addressing a wider range of diseased anatomy.

22 Dec 2011

Scott & White gynecologist receives Honorary Fellowship from RANZCOG

Bob L. Shull, M.D., gynecologist and director of fellowship training in female pelvic medicine and reconstructive pelvic surgery at Scott & White Healthcare in Temple, Texas, has received an Honorary Fellowship from the Royal Australian and New Zealand College of Obstetricians and Gynaecologists.

22 Dec 2011

Researchers evaluate Clade C HIV envelope protein in Phase I trial

In the first clinical trial of an injectable vaccine containing trimeric HIV envelope protein (gp140) relevant to the predominant strain of HIV in Africa, researchers from four UK academic centers (St George's University London, Imperial College, Hull York Medical School (HYMS; University of York) and the Medical Research Council Clinical Trial Unit) and from the Infectious Disease Research Institute (IDRI) have come together to evaluate whether the vaccine is safe for use in human volunteers.

22 Dec 2011

Calif. gets $118 million for high risk pool; Mo. legislator urges suspension of health exchange plans

The federal funds will help California provide coverage to residents with medical problems. In Missouri, a state senator suggests that officials not make any more plans on the state health exchange until the Supreme Court rules on the legality of the federal health law.

22 Dec 2011

Gottlieb surgeon's evaluations of top five winter sports

The first day of winter is Wednesday, December 21, and many states are bracing for a season of snow and ice. Broken bones from snowboarding and sledding top the list of common visits to the Emergency Department (ED) during the winter months. According to the Centers for Disease Control and Prevention, one-quarter of all emergency hospital visits are attributed to snowboarding accidents, and half of all cases were for broken bones and sprains.

22 Dec 2011

CNVs appear to play a significant role in early onset bipolar disorder

An international team of scientists, led by researchers at the University of California, San Diego School of Medicine, reports that abnormal sequences of DNA known as rare copy number variants, or CNVs, appear to play a significant role in the risk for early onset bipolar disorder.

22 Dec 2011

Study measures brain activity in infants to better understand their pain response

Recently, the accuracy of current methods of pain assessment in babies have been called into question. New research from London-area hospitals and the University of Oxford measures brain activity in infants to better understand their pain response.

22 Dec 2011

Scientists model brain structure to help computers recognize objects

An essential question confronting neuroscientists and computer vision researchers alike is how objects can beidentified by simply "looking" at an image. Introspectively, we know that the human brain solves this problem very well. We only have to look at something to know what it is.

22 Dec 2011

Current U.S. rules, regulations sufficient to protect volunteers in federally funded research, report says

A report released last week by the Presidential Commission for the Study of Bioethical Issues examining federally sponsored research involving human volunteers, called "Moral Science: Protecting Participants in Human Subjects Research," said that "current rules and regulations provide adequate safeguards to mitigate risk," "recommended 14 changes to current practices to better protect research subjects, and called on the federal government to improve its tracking of research programs supported with taxpayer dollars," according to a Commission press release.

22 Dec 2011

Truths and myths about pregnancy, obesity

Ironically, despite excessive caloric intake, many obese women are deficient in vitamins vital to a healthy pregnancy. This and other startling statistics abound when obesity and pregnancy collide. Together, they present a unique set of challenges that women and their doctors must tackle in order to achieve the best possible outcome for mom and baby.

22 Dec 2011

FDA approves Infrascanner to detect life-threatening brain bleeding

Battlefield corpsmen and medical professionals across the country gained a valuable tool last week, as the Food and Drug Administration approved the first hand-held device to detect life-threatening bleeding in the brain.

22 Dec 2011

ORNL tool reveals previously undiscovered role of retinoblastoma

Armed with a new ability to find retinal anomalies at the cellular level, neurobiologists at St. Jude Children's Research Hospital have made a discovery they hope will ultimately lead to a treatment for cancer of the retina.

22 Dec 2011

Medical News

Researchers map every apparent physical interaction of HIV virus with human cells

Report outlines steps for transition of PEPFAR service delivery to S. African government

Scientists discover N-cadherin as promising therapeutic target for pancreatic cancer

Researchers discover how c-MYC facilitates tumor growth

Autism Speaks announces 47 new ASD research grants

Study hopes to explain premature births and failed inductions of labour

Government, humanitarian agencies respond to flooding in Philippines, warn of disease threat

JAMA commentary argues that vitamin therapy still plays a role in reducing stroke

TriVascular treats first Canadian patients with Ovation Abdominal Stent Graft

Scott & White gynecologist receives Honorary Fellowship from RANZCOG

Researchers evaluate Clade C HIV envelope protein in Phase I trial

Calif. gets $118 million for high risk pool; Mo. legislator urges suspension of health exchange plans

Gottlieb surgeon's evaluations of top five winter sports

CNVs appear to play a significant role in early onset bipolar disorder

Study measures brain activity in infants to better understand their pain response

Scientists model brain structure to help computers recognize objects

Current U.S. rules, regulations sufficient to protect volunteers in federally funded research, report says

Truths and myths about pregnancy, obesity

FDA approves Infrascanner to detect life-threatening brain bleeding

ORNL tool reveals previously undiscovered role of retinoblastoma

Membrane proteins in focus: Turning high-risk targets into routine workflows

How metabolic phenotyping can detect viral infections in minutes

Directed enzyme evolution and the Nobel Prize: Making enzymes evolve in the lab

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