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Pupil can constrict without any input from brain

You've seen it on television: A doctor shines a bright light into an unconscious patient's eye to check for brain death. If the pupil constricts, the brain is OK, because in mammals, the brain controls the pupil. Or does it? Now, researchers at Johns Hopkins have discovered that in most mammals, in fact in most vertebrates, the pupil can constrict without any input from the brain.

3 Nov 2011

Allergy shots are cost-effective and deliver relief in weeks

Allergy shots, an age-old treatment for allergy sufferers, are getting a shot in the arm from new research. This proven therapy saves money; accelerated schedules deliver relief in weeks, rather than months; and alternative methods are on the horizon, according to allergists at the annual scientific meeting of the American College of Allergy, Asthma and Immunology in Boston, Nov 3-8.

3 Nov 2011

Novel indirect screener can identify women at risk for illicit drug use

A team of researchers at Wayne State University's Parent Health Lab in the School of Medicine have developed a novel indirect screener that identifies women at risk for drug use by evaluating correlates of illicit drug use rather than drug use itself. In phase I testing, this new screener proved to be more sensitive than any alternative approach at detecting recent drug use.

3 Nov 2011

Clinical-grade viral vector can cure choroideremia

Researchers at Ohio State University Medical Center and Nationwide Children's Hospital have developed a viral vector designed to deliver a gene into the eyes of people born with an inherited, progressive form of blindness that affects mainly males.

3 Nov 2011

Replacing short auto trips with bicycle trips would yield major health benefits

Cutting out short auto trips and replacing them with mass transit and active transport would yield major health benefits, according to a study just published in the scientific journal Environmental Health Perspectives.

3 Nov 2011

UCSD, Rady Children's to host Building Sustainable Surgical Systems conference

UC San Diego School of Medicine and Rady Children's Hospital are hosting a joint Alliance for Surgery and Anesthesia (ASAP) and World Health Organization Global Initiative for Emergency and Essential Surgical Care (GIEESC) meeting November 9-11, 2011.

3 Nov 2011

OECD with Eurostat, WHO publishes manual on accounting practices for health service spending

The Organisation for Economic Co-operation and Development (OECD) "is urging all countries to meet a global standard in the way they account for their health service spending," BMJ reports, adding, "In October the OECD, in collaboration with Eurostat and the World Health Organization, published what it describes as a 'monster of a manual' called A System of Health Accounts.

3 Nov 2011

FEIBA drug safe and effective for patients with hemophilia A

An international research team led by Dr. Cindy Leissinger of Tulane University School of Medicine, along with Dr. Alessandro Gringeri from the University of Milan, has found that a drug commonly used to treat bleeding events in people with a type of severe hemophilia can also be used to prevent such events from happening in the first place.

3 Nov 2011

MSCs can be reprogrammed to have enhanced survival and therapeutic efficacy

Chinese stem cell scientists have published new research that improves the survival and effectiveness of transplanted stem cells. The research led by Dr Hsiao Chang Chan, from the Chinese University of Hong Kong, is published in Stem Cells.

3 Nov 2011

New laser technique could create tissue scaffolds, microneedles

In the emerging field of tissue engineering, scientists encourage cells to grow on carefully designed support scaffolds. The ultimate goal is to create living structures that might one day be used to replace lost or damaged tissue, but the manufacture of appropriately detailed scaffolds presents a significant challenge that has kept most tissue engineering applications confined to the research lab.

3 Nov 2011

Ivacaftor drug improves lung function in people with cystic fibrosis

A new study has confirmed that the drug, ivacaftor (VX-770), significantly improves lung function in some people with cystic fibrosis (CF). The results of the phase III clinical trial study, "A CFTR Potentiator in Patients with Cystic Fibrosis and the G551D Mutation," led by Bonnie W. Ramsey, MD of Seattle Children's Research Institute and the University of Washington, were published today in the New England Journal of Medicine.

3 Nov 2011

Combination of Mediterranean diet, physical activity can help improve symptoms of OSAS

Eating a Mediterranean diet combined with physical activity can help to improve some of the symptoms of sleep apnoea, according to new research.

3 Nov 2011

Promedior's Pentraxin-2 effectively suppresses liver fibrosis

Promedior, Inc., a clinical stage biotechnology company developing novel therapies to treat fibrotic, inflammatory and neovascular diseases, today announced that data from preclinical studies of Serum Amyloid P (Pentraxin-2) will be presented at the Annual Meeting of the American Association for the Study of Liver Diseases (AASLD 2011), being held November 4-8, 2011, in San Francisco, CA.

3 Nov 2011

Study reveals new role for the 'hormone of love'

Much of the body's chemistry is controlled by the brain - from blood pressure to appetite to food metabolism. In a study published recently in Developmental Cell, a team of scientists led by Dr. Gil Levkowitz of the Weizmann Institute has revealed the exact structure of one crucial brain area in which biochemical commands are passed from the brain cells to the bloodstream and from there to the body. In the process, they discovered a surprising new role for the 'hormone of love,' showing that it helps to direct the development of this brain structure.

3 Nov 2011

UC Merced professor designs powerful chemical inhibitor against HIV

In a significant step toward reducing the threat of HIV, UC Merced Professor Patricia LiWang has designed what may be the most effective chemical inhibitor against infection of the virus.

3 Nov 2011

Biomoda submits new U.S. Patent application for CyPath lung cancer assay

Cancer diagnostics company Biomoda, Inc. filed an application for a new U.S. Patent that refines the use of fluorescent microscopy to increase the accuracy, sensitivity and specificity of the CyPath diagnostic assay for lung cancer.

3 Nov 2011

Nearly half of pregnant women in Southern China's poor areas do not get tested for syphilis, study shows

"Nearly half of pregnant women do not get tested for syphilis in poor areas of southern China where the sexually transmitted disease has seen a resurgence, researchers said Wednesday" in a study published in the WHO's November 2011 Bulletin, the Associated Press/Washington Post reports.

3 Nov 2011

Medtronic initiates CoreValve System trial to treat severe aortic stenosis in Japan

Medtronic, Inc. today announced the first implant in a clinical trial in Japan that will evaluate the safety and effectiveness of the Medtronic CoreValve System.

From Medtronic 3 Nov 2011

Edwards Lifescience receives FDA approval for Sapien Transcatheter Heart Valve

The U.S. Food and Drug Administration today approved the first artificial heart valve that can replace an aortic heart valve damaged by senile aortic valve stenosis without open-heart surgery.

3 Nov 2011

Affective symptoms can help diagnose early psychotic disorders

Functional psychosis can be diagnosed from the first indications of the patient, thanks to affective symptomatology. Depressive moods, hyperactivity and lack of concentration are affective symptoms that can present themselves during the first psychotic episodes, and the presence or absence of any of them may contribute to differentiating, at an early stage, between the different variations of the mental disease.

3 Nov 2011