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Solid organ transplant may increase risk of cancer

Patients who have received a solid organ transplant, such as kidney, liver, heart or lung, have an overall cancer risk that is double that of the general population, with an increased risk for many different types of malignancies, according to a study in the November 2 issue of JAMA.

2 Nov 2011

Congress should grant PEPFAR future security because program is 'desperately needed'

In this CNN opinion piece, Julian Zelizer, an author and professor of history and public affairs at Princeton University, reports on how, "as the super-committee deliberates over how to reduce the deficit and other congressional committees struggle to cut spending, the fate of important programs," such as PEPFAR, "hangs in the balance."

2 Nov 2011

TERE1 gene mutation also contributes to invasive bladder cancer

Research conducted by Dr. Jayne S. Weiss, Professor and Chair of Ophthalmology at LSU Health Sciences Center New Orleans, and colleagues has found that a defect in a gene involved in a rare disease of the cornea also contributes to the progression of invasive bladder cancer.

2 Nov 2011

NIH-funded project to discover biomarkers for type 2 diabetes

Arizona State University will lead a four-year, $5 million expanded initiative sponsored by the National Institutes of Health to discover proteins, or biomarkers, to help predict cardiovascular disease and to assess potential new treatments in people with type 2 diabetes.

2 Nov 2011

Age is no longer a barrier to allogeneic stem cell transplantation

Age alone no longer should be considered a defining factor when determining whether an older patient with blood cancer is a candidate for stem cell transplantation. That's the conclusion of the first study summarizing long-term outcomes from a series of prospective clinical trials of patients age 60 and over who were treated with the mini-transplant, a "kinder, gentler" form of allogeneic (donor cell) stem cell transplantation developed at Fred Hutchinson Cancer Research Center.

2 Nov 2011

Health risk associated with harmful substances in food may be underestimated

Mice are often used to test whether substances in food are harmful to humans. This requires that mice and humans metabolise substances in the same way. Humans have certain enzymes in more parts of the body than mice. The health risk associated with harmful substances in food may therefore be underestimated.

2 Nov 2011

Alliances form among super committee members

Reuters reports that three Republicans and three Democrats are joining together in an effort to develop the framework of a deal themselves. Meanwhile, an outside organization - the AFL-CIO - is launching a campaign to defeat any Medicare, Medicaid or Social Security cuts the panel may ultimately propose. And, according to Politico, Social Security is in play as the panel's deliberations continue.

2 Nov 2011

Researchers identify small-molecule drug candidates for many metabolic conditions

A new discovery by Californian scientists may lead to a pharmaceutical breakthrough for a wide range of illnesses that involve the hydration of cells that line the inner surfaces of our body's organs and tissues. In a new report appearing in the FASEB Journal, the researchers describe how they used high-throughput screening to identify small-molecule drug candidates which help cells bypass defective channels that normally move salt and water through cell membranes.

2 Nov 2011

Zanzibar's Islamic leaders use Qur'an to shift attitudes about sex, contraception, HIV/AIDS

The Guardian's "Poverty Matters Blog" examines how religious leaders on the island of Zanzibar, a semi-autonomous part of Tanzania, are using the Qur'an to shift attitudes about the issues of sex, contraception, and HIV/AIDS in an effort to reduce HIV infection, improve maternal health and curb rapid population growth. "Their aim is to shift deep-rooted views in their devout Islamic society that contraception is a sin," according to the blog.

2 Nov 2011

First study to evaluate mycoestrogens in young girls

Puberty is a time in a girl's life considered highly sensitive to stimulation by the hormone estrogen and a critical window during which estrogen exposure could greatly influence the risk of breast cancer later in life. An early onset of puberty also has been consistently shown in studies to increase the risk of breast cancer.

2 Nov 2011

State roundup: Ga., Minn. move slowly on exchanges

The entire Massachusetts congressional delegation is asking CMS to preserve the level of safety net funding and provider payments as the state tries to renew its Medicaid waiver. "We are concerned that changes proposed by CMS could significantly threaten payments to Massachusetts health care providers providing care for the most vulnerable populations," Sens. John Kerry and Scott Brown and the 10 House members in the state's delegation wrote.

2 Nov 2011

Study finds multidrug-resistant Acinetobacter baumannii in 48% of infected patient rooms

Multidrug-resistant Acinetobacter baumannii (MDR-AB) was found in the environment of 48 percent of the rooms of patients colonized or infected with the pathogen, according to a new study published in the November issue of the American Journal of Infection Control, the official publication of APIC - the Association for Professionals in Infection Control and Epidemiology.

2 Nov 2011

Home health payments will fall 2.3% in 2012

The pay cut for home health agencies was announced in a regulation that was issued Monday. Although this reduction is less than initially proposed and will be phased in over two years, industry voices described it as "severe."

2 Nov 2011

Elevated body temperature helps certain types of immune cells to work better

With cold and flu season almost here, the next time you're sick, think twice before taking something for your fever. That's because scientists have found more evidence that elevated body temperature helps certain types of immune cells to work better.

2 Nov 2011

Obama takes action to address drug shortages

President Barack Obama issued an executive order Monday directing the Food and Drug Administration to, among other steps, speed up reviews of manufacturers' applications to begin or alter production of a drug in potentially short supply.

2 Nov 2011

Prostate cancer patients with bone metastases benefit from repeated 188Re-HEDP therapy

For prostate cancer patients with bone metastases, repeated administrations of radionuclide therapy with 188Re-HEDP are shown to improve overall survival rates and reduce pain, according to new research published in the November issue of The Journal of Nuclear Medicine.

2 Nov 2011

Early retirees' health insurance fund running out

A federal report predicts this $5 billion account created as part of the health law will be drained by 2012. In related news, one senator criticizes the program's handling. Also drawing criticism are exchange regulations, which advocates say could undermine the law's goal of expanding health insurance. Meanwhile, the Department of Health and Human Services finalized standards - part of the administration's efforts to reduce health disparities - to track factors that affect people's health.

2 Nov 2011

Johns Hopkins breast cancer researcher wins BioMaryland LIFE Prize

A Johns Hopkins breast cancer researcher is the recipient of a $50,000 award designed to encourage rapid translation of her basic research on biomarkers into a commercially available test that could predict the best treatment options for some women with breast cancer.

2 Nov 2011

Debating 'RomneyCare's' parenthood

The video is a lively - though civil - Republican-Democrat debate about whether it's fair to consider Massachusetts health reform as the "parent" of the federal health overhaul. As CommonWealth magazine executive editor Michael Jonas introduces it: Talking over the issue are Tim Murphy, who was Romney's secretary of health and human services and John McDonough, who was in the thick of the 2006 reform as director of Health Care for All.

2 Nov 2011

ADHD medications do not increase risk of heart attack in children, young adults

Attention Deficit Hyperactivity Disorder (ADHD) medications do not increase the risk for heart disease or heart attack in children and young adults, according to a Vanderbilt study of 1.2 million patients taking drugs including Ritalin, Adderall, Concerta and Strattera between 1998 and 2005.

2 Nov 2011