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Stopping necroptosis in keratinocytes prevents skin inflammation

The outer layer of the skin, called the epidermis, forms a critical physical and immunological wall that serves as the body's first line of defense against potentially harmful microorganisms. Most of the epidermis consists of cells called keratinocytes that build a mechanical barrier but also perform immune functions.

14 Oct 2011

Faster cerebral cortex growth in infancy may lead to higher intelligence

New research suggests the growth rate of the brain's cerebral cortex in babies born prematurely may predict how well they are able to think, speak, plan and pay attention later in childhood. The research is published in the October 12, 2011, online issue of Neurology®, the medical journal of the American Academy of Neurology.

14 Oct 2011

Oncobiologics signs two major pharmaceutical agreements

Oncobiologics announced today that it has signed two major agreements. The first is with Parilis Biopharmaceuticals, an early-stage biotech company, and involves worldwide licensing for an undisclosed biotherapeutic product. The second is with a US based large pharmaceutical company to conduct research focused on solving issues related to downstream processing of monoclonal antibodies.

14 Oct 2011

Dual drug sneaks across the blood-brain barrier to fight HIV

In an advance toward eliminating pockets of infection in the brain that help make HIV disease incurable, scientists report the development of new substances that first plug the biological vacuum cleaner that prevents anti-HIV drugs from reaching the brain and then revert to an active drug to treat HIV.

14 Oct 2011

Continued access to hospital pharmacists increases patient safety and care

Making sure patients and their primary caregivers are ready for the return home is critical in the recovery process. So Gottlieb Memorial Hospital, part of Loyola University Health System, is adding an extra measure of patient safety and care by offering increased communication with inpatient pharmacists.

14 Oct 2011

Cylene advances preclinical development of CX-5461 for treatment of cancer

Cylene Pharmaceuticals, Inc. has advanced its targeted, non-genotoxic, activator of p53 for the treatment of leukemias, lymphomas and multiple myeloma through formal preclinical development, the Company announced today.

14 Oct 2011

Bonuses tied to Medicare Advantage's star system reward insurers on quality marks

For the first time, a government-backed quality rating will have a financial meaning to health insurance companies looking to attract millions of older Americans to privately run Medicare coverage next year.

14 Oct 2011

Reducing medicine to economics makes mockery of doctor-patient bond

Physicians who once only grappled with learning the language of medicine must now also cope with a health care world that has turned hospitals into factories and reduced clinical encounters to economic transactions, two Beth Israel Deaconess Medical Center physicians lament.

14 Oct 2011

DRC worst off among 26 countries facing 'alarming' or 'extremely alarming' hunger levels, according to new Global Hunger Index

"Twenty-six countries have 'alarming' or 'extremely alarming' hunger levels, with the situation deteriorating particularly badly in Democratic Republic of Congo (DRC), according to this year's Global Hunger Index," AlertNet reports.

14 Oct 2011

Noven claims patent infringement over Daytrana, files lawsuit against Watson

Noven Pharmaceuticals, Inc. announced today that it has filed a lawsuit in the U.S. District Court of New Jersey against Watson Pharmaceuticals for infringement of certain Noven patents by Watson.

14 Oct 2011

One in six mobile phones in the UK is contaminated with fecal bacteria

One in six mobile phones in Britain is contaminated with faecal matter, according to new research released ahead of Global Handwashing Day.

14 Oct 2011

Study: miR-34b gene associated with aggressive form of melanoma

A certain microRNA gene, miR-34b, could be a useful biomarker in early diagnosis of the most lethal forms of melanoma, according to new research published by KGI Professor Animesh Ray and his research collaborators.

14 Oct 2011

Maternal attachment, television viewing influence adolescents' sexual attitudes

Can teenagers' relationship with their mother protect them from the negative effects that television has on their sexual attitudes? It depends on their gender, according to a new study by Laura Vandenbosch and Steven Eggermont, from Katholieke Universiteit Leuven in Belgium. For girls, a good relationship with mom is protective.

14 Oct 2011

Longer looks: Miss. ballot-initiative on abortion; personal fortune may have helped Herman Cain battle cancer; for doctors, breaking up is hard to do

One evening in late September John Perkins, a veteran of the civil-rights movement, attended a rally at a Baptist church in Jackson in support of what he called "a total justice issue," … It was concerned with Amendment 26, a measure on Mississippi's ballot this November that defines a person as being "every human being from the moment of fertilisation, cloning or the functional equivalent thereof". The reason for the measure is straightforward; its consequences less so. The Supreme Court, in its landmark Roe v Wade ruling in 1973, held that the right of a woman to terminate her pregnancy in the first trimester was guaranteed by her constitutional right to privacy.

14 Oct 2011

Limited decision-making ability of individual cells is bolstered in masses

Researchers from Johns Hopkins have quantified the number of possible decisions that an individual cell can make after receiving a cue from its environment, and surprisingly, it's only two.

14 Oct 2011

Tips to strengthen family connections

Combined with increasingly hectic work, school and extracurricular schedules, the advent of wireless technology has led to less quality time between parents and children. University of Missouri human development specialists say powering down digital devices is a vital step in maintaining family relationships and health.

14 Oct 2011

Patients with episodic gallbladder pain may benefit from cholecystectomy

According to a new study in Clinical Gastroenterology and Hepatology, better understanding of a patient's abdominal pain could help physicians know which patients will benefit most from surgical removal of the gallbladder.

14 Oct 2011

UNH scientists to explore small-scale ecological experiments

University of New Hampshire scientists have received National Science Foundation (NSF) funding to explore how small-scale ecological experiments can be applied to understand the behavior of entire ecosystems, part of the agency's nascent effort to investigate large-scale biological responses to climate and land-use change.

14 Oct 2011

AMCs must make systematic changes to improve quality of life, productivity of their faculty

Academic medical centers (AMCs) must make systematic changes to improve quality of life—and thus productivity—of their faculty, according to a commentary that will appear in the October 12 issue of Science Translational Medicine.

14 Oct 2011

New technique stimulates stem cells after liver transplant to prevent rejection

Johns Hopkins researchers have developed a way to stimulate a rat's stem cells after a liver transplant as a means of preventing rejection of the new organ without the need for lifelong immunosuppressant drugs.

14 Oct 2011