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PharmAthene completes 1,500 liter engineering production run for SparVax anthrax vaccine

PharmAthene, Inc. announced today that it has achieved significant progress in the development of its second generation anthrax vaccine, SparVax.

12 Sep 2011

Human gliomas release excess levels of glutamate and trigger seizures

Glioma, one of the most deadly and common types of brain tumor, is often associated with seizures, but the origins of these seizures and effective treatments for them have been elusive. Now a team funded by the National Institutes of Health has found that human gliomas implanted in mice release excess levels of the brain chemical glutamate, overstimulating neurons near the tumor and triggering seizures.

12 Sep 2011

Candidate malaria vaccine represents 'potentially encouraging anti-malaria strategy,' researchers say

A team of researchers led by Stephen Hoffman of Sanaria Inc. has created a candidate malaria vaccine against Plasmodium falciparum, the most deadly of the malaria parasites, using live but weakened parasites that "represents a potentially encouraging anti-malaria strategy," an NIH/National Institute of Allergy and Infectious Diseases press release reports.

12 Sep 2011

Researchers describe new function of HCN channels in the heart

The heartbeat is the result of rhythmic contractions of the heart muscle, which are in turn regulated by electrical signals called action potentials. Action potentials result from the controlled flow of ions into heart muscle cells (depolarization) through channels in their membranes, and are followed by a compensating reverse ion current (repolarization), which restores the original state. If the duration of the repolarization phase is not just right, the risk of ventricular arrhythmia and sudden cardiac death increases significantly.

12 Sep 2011

Taiwan residents to receive two month free access to The Cochrane Library

Taiwan residents will receive free access to The Cochrane Library in August and September 2011, in collaboration with the Taiwan Evidence Based Medicine Association at their Annual Conferencein September, whereDr. Charles Young, VP and Publishing Director for Global Clinical Solutions, atThe Cochrane Library's publisher, Wiley-Blackwell, will be presenting a session.

12 Sep 2011

Access to lifesaving generic medicines threatened by U.S. trade pact

"Access to affordable lifesaving medicines will be threatened where they are needed most -- in parts of the developing world -- if the U.S. insists on implementing restrictive intellectual property policies in the Trans-Pacific Partnership (TPP) trade agreement," states a press release from Doctors Without Borders.

12 Sep 2011

Common genetic variant may predispose people to acute dissections

Richard Holbrooke, John Ritter, Lucille Ball, Jonathan Larson and Great Britain's King George II were all taken by the same silent killer: an acute aortic dissection. Now, scientists led by researchers at The University of Texas Health Science Center at Houston and Baylor College of Medicine have found an association with a common genetic variant in the population that predisposes people to acute dissections and can approximately double a person's chances of having the disease.

12 Sep 2011

WSU researcher receives $418,000 NINDS grant to study spinal muscular atrophy

Graham Parker, Ph.D., assistant professor of research in the Department of Pediatrics at Wayne State University's School of Medicine, was awarded $418,000 from the National Institute of Neurological Disorders and Stroke of the National Institutes of Health to study how a particular gene might be involved in the progression of spinal muscular atrophy (SMA) - the number one genetic killer of children younger than 2 years old.

12 Sep 2011

Scientists identify 28 blood pressure-associated genetic variants

A new report from scientists at Massachusetts General Hospital (MGH) and their colleagues in centers around the world finds that common variants in 28 regions of DNA are associated with blood pressure in human patients.

12 Sep 2011

UMSOM to receive FDA approval for whole parasite malaria vaccine clinical trials

For the first time, a malaria vaccine that uses the entire malaria parasite has proven safe and shown promise to produce a strong immune response in a clinical trial, according to a new study co-authored by researchers at the University of Maryland School of Medicine Center for Vaccine Development.

12 Sep 2011

Febrile seizures in children may be linked to respiratory alkalosis

New research shows that febrile seizures in children may be linked to respiratory alkalosis, indicated by elevated blood pH and low carbon dioxide levels caused by hyperventilation, and independent of the underlying infection severity.

12 Sep 2011

Researchers identify 29 DNA sequence variations linked with blood pressure

A study involving more than 200,000 people worldwide has identified 29 DNA sequence variations in locations across the human genome that influence blood pressure.

12 Sep 2011

Study: Regional differences exist in treatment of patients with acute cerebral infarction

Considerable regional differences exist in the treatment of patients with acute cerebral infarction. This is the finding presented by Erwin Stolz and his co-authors in the current issue of Deutsches Ärzteblatt International.

12 Sep 2011

Australian scientists create iron-rich 'super rice'

Scientists from three universities in South Australia and the University of Melbourne have created genetically modified rice that "has up to four times more iron than conventional rice and twice as much zinc" in an effort to "provide a solution to the iron and zinc deficiency disorders that affect billions of people throughout the world," News Corp Australian Papers/Fox News reports.

12 Sep 2011

NIH awards $13M grant to BMC for brain abnormality study in former ELGANS

Researchers and clinicians from Boston Medical Center (BMC) have been awarded a four year, more than $13 million grant from the National Institutes of Health (NIH) to study neurological and brain abnormalities in former extremely low gestational age newborns.

12 Sep 2011

Researchers discover 16 new gene regions that influence blood pressure

Findings, published today in Nature and Nature Genetics by the International Consortium for Blood Pressure Genome-Wide Association Studies represent a major advance in our understanding of the inherited influences on blood pressure and offer new potential therapeutic targets for prevention of heart disease and stroke - the biggest cause of death worldwide.

12 Sep 2011

NASA selects nine projects to investigate space radiation's effect on human explorers

NASA is funding nine proposals from eight states to investigate space radiation's effect on human explorers. The proposals from researchers in California, Colorado, Florida, Georgia, Maryland, Massachusetts, New York and Texas have a total value of approximately $12 million.

12 Sep 2011

Study pinpoints relationship between primary brain tumors and onset of epileptic seizures

New research from the University of Alabama at Birmingham pinpoints the relationship between primary brain tumors and the onset of epileptic seizures and reveals that a drug used to treat Crohn's disease inhibits those seizures and may be able to slow a tumor's growth.

12 Sep 2011

Nektar announces positive results from NKTR-102 Phase 2 study on metastatic breast cancer

Nektar Therapeutics announced today that positive results from the company's Phase 2 clinical study of NKTR-102 in patients with metastatic breast cancer were presented at the ASCO 2011 Breast Cancer Symposium in San Francisco, California.

12 Sep 2011

Former president of Chile, Michelle Bachelet, on the importance of family planning as global population approaches 7 billion

The GlobalPost's "Global Pulse" blog reports on an event held on Wednesday at the Aspen Institute in Washington, D.C., entitled "7 Billion: Conversations that Matter," at which Michelle Bachelet, former president of Chile and now the under secretary-general and executive director of UN Women, spoke about the importance of family planning as the global population approaches the seven billion mark.

12 Sep 2011

Medical News

PharmAthene completes 1,500 liter engineering production run for SparVax anthrax vaccine

Human gliomas release excess levels of glutamate and trigger seizures

Candidate malaria vaccine represents 'potentially encouraging anti-malaria strategy,' researchers say

Researchers describe new function of HCN channels in the heart

Taiwan residents to receive two month free access to The Cochrane Library

Access to lifesaving generic medicines threatened by U.S. trade pact

Common genetic variant may predispose people to acute dissections

WSU researcher receives $418,000 NINDS grant to study spinal muscular atrophy

Scientists identify 28 blood pressure-associated genetic variants

UMSOM to receive FDA approval for whole parasite malaria vaccine clinical trials

Febrile seizures in children may be linked to respiratory alkalosis

Researchers identify 29 DNA sequence variations linked with blood pressure

Study: Regional differences exist in treatment of patients with acute cerebral infarction

Australian scientists create iron-rich 'super rice'

NIH awards $13M grant to BMC for brain abnormality study in former ELGANS

Researchers discover 16 new gene regions that influence blood pressure

NASA selects nine projects to investigate space radiation's effect on human explorers

Study pinpoints relationship between primary brain tumors and onset of epileptic seizures

Nektar announces positive results from NKTR-102 Phase 2 study on metastatic breast cancer

Former president of Chile, Michelle Bachelet, on the importance of family planning as global population approaches 7 billion

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

A new method to measure intracellular water in biological systems

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