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Lack of kidney dopamine leads to high blood pressure and shorter life span

The neurotransmitter dopamine is best known for its roles in the brain - in signaling pathways that control movement, motivation, reward, learning and memory.

20 Jul 2011

New transgenic mouse could predict toxicity of targeted cancer drugs

Only one in twenty cancer drugs makes its way from the laboratory to become an approved pharmaceutical product. The majority of new agents are only shown to be unsuitable in the later phases of clinical development which would explain the exorbitantly high development costs of 500 to 600 million euros per new cancer drug.

20 Jul 2011

Millennium submits VELCADE sNDA to FDA to add OS data for previously untreated multiple myeloma

Millennium: The Takeda Oncology Company with its parent company Takeda Pharmaceutical Company Limited today announced the submission of a supplemental New Drug Application (sNDA) with the U.S. Food and Drug Administration for VELCADE® (bortezomib) for injection to add overall survival data after a five-year follow up to the product label.

20 Jul 2011

High rates of osteoarthritis in athletes linked to femur damage during adolescence

New study links high rates of osteoarthritis in athletes to femur damage during adolescence, as a result of participation in high-intensity sports.

20 Jul 2011

Nuclear Factor I/B appears to drive progression of small cell lung cancer

A major challenge for cancer biologists is figuring out which among the hundreds of genetic mutations found in a cancer cell are most important for driving the cancer's spread.

20 Jul 2011

State roundup: Maine, Minn. GOP want insurance changes

Maine Gov. Paul LePage (R) told an enthusiastic crowd at the Heritage Foundation on Monday that his Republican administration thinks "taking off the shackles" from insurers is the way to keep healthcare costs low for rural residents.

20 Jul 2011

Falls, balance problems linked to early stages of Alzheimer's

Falls and balance problems may be early indicators of Alzheimer's disease, researchers at Washington University School of Medicine in St. Louis reported July 17, 2011, at the Alzheimer's Association International Conference on Alzheimer's Disease in Paris.

20 Jul 2011

Valeant, sanofi-aventis partner to market and distribute Zuacta cream

Valeant Pharmaceuticals International, Inc. announced today that its subsidiary, Valeant International SRL, has entered into an agreement with sanofi-aventis Canada Inc.

20 Jul 2011

Patients who use anti-depressants more likely to suffer relapses

Patients who use anti-depressants are much more likely to suffer relapses of major depression than those who use no medication at all, concludes a McMaster researcher.

20 Jul 2011

Gel Company, Biomerix partner to market and distribute 3D Scaffold

Biomerix Corporation and Gel Company today announced a strategic distribution agreement for the Biomerix 3D Scaffold, a novel three-dimensional tissue scaffold. Under the agreement, Gel Company will market and distribute the Biomerix 3D Scaffold to researchers in the life science community across the United States.

20 Jul 2011

Altogen Labs introduces pyrosequencing services for hospitals, research institutions

Altogen Labs, a biology contract research organization and provider of pre-clinical research services, announced its launch of a pyrosequencing service today.

20 Jul 2011

CEL-SCI expands licensing agreement with Teva for Multikine cancer drug

CEL-SCI Corporation announced today that it has expanded the licensing agreement with Teva Pharmaceutical Industries Ltd. for its cancer drug Multikine.

20 Jul 2011

Tips for preventing heat-related illness

With "feels-like" temperatures approaching or exceeding 100 degrees forecast for parts of Pennsylvania this week, the Department of Health is reminding all Pennsylvanians of important steps they can take to protect their health.

20 Jul 2011

Tyco reaches agreement to acquire Chemguard

Tyco International Ltd. announced today that it has reached an agreement to acquire privately-held Chemguard, Inc., a leading provider of firefighting foam concentrates and equipment, foam systems, services and specialty chemicals. Chemguard will be integrated into Tyco's Fire Protection Products business unit.

20 Jul 2011

Viewpoints: Suggestions for reducing Medicare spending; Medicaid cuts hurt; personal health responsibility

Over the past months, Republicans enjoyed enormous advantages. Opinion polls showed that voters are eager to reduce the federal debt, and they want to do it mostly but not entirely through spending cuts. There was a Democratic president eager to move to the center. He floated certain ideas that would be normally unheard of from a Democrat.

20 Jul 2011

DNA vaccine developer Coridon in U.S. collaboration

DNA vaccine development company Coridon Pty Ltd. today announced that it has entered into a research collaboration agreement with The Ohio State University to progress its Epstein Barr Virus (EBV) project.

19 Jul 2011

Surgeons' behavior in operating room affects patient outcomes, healthcare costs

A surgeon's behavior in the operating room affects patient outcomes, healthcare costs, medical errors and patient- and staff-satisfaction, says a commentary in the July issue of Archives of Surgery.

19 Jul 2011

Two key genes may help prevent childhood leukemia

Researchers at The University of Western Ontario have identified genes that may be important for preventing childhood leukemia. Acute lymphoblastic leukemia (ALL) is a cancer of the blood that occurs primarily in young children.

19 Jul 2011

Main Street completes $6.5 million new portfolio investment

Main Street Capital Corporation announced today that it has completed a new portfolio investment totaling $6.5 million.

19 Jul 2011

Sigma introduces CompoZr Targeted Integration Kit – mRosa26

Sigma Life Science, the innovative biological products and services research business of Sigma-Aldrich Corporation today announced the launch of CompoZr Targeted Integration Kit – mRosa26, which can precisely and rapidly integrate transgenes into the mouse genome at the Rosa26 safe harbor locus.

19 Jul 2011