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Gilead to amend design of ongoing clinical trials against chronic hepatitis C

Gilead Sciences, Inc. today announced that, in consultation with the U.S. Food and Drug Administration (FDA), the company will amend the design of ongoing clinical trials to discontinue dosing of GS 9190 in hepatitis C-infected patients who are receiving that compound in combination with pegylated interferon and ribavirin, and another direct-acting antiviral agent.

5 Sep 2011

Teenagers use medicines frequently without receiving targeted information about risks and benefits

A large proportion of teenagers regularly and frequently take some form of medication without receiving targeted information about the risks and benefits, according to a review of current research, to be presented at the annual congress of the International Pharmaceutical Federation.

5 Sep 2011

C. sporogenes bacterium could be used as vehicle to deliver drugs in frontline cancer therapy

A bacterial strain that specifically targets tumours could soon be used as a vehicle to deliver drugs in frontline cancer therapy. The strain is expected to be tested in cancer patients in 2013 says a scientist at the Society for General Microbiology's Autumn Conference at the University of York.

5 Sep 2011

Inflammation boosts activity of two proteins that can normalize blood sugar in diabetics

Increased low-grade inflammation in the body resulting from obesity is widely viewed as contributing to type 2 diabetes. Going against this long-held belief, researchers from Children's Hospital Boston report that two proteins activated by inflammation are actually crucial for maintaining good blood sugar levels - and that boosting the activity of these proteins can normalize blood sugar in severely obese and diabetic mice.

5 Sep 2011

IKEPLUS immunization completely eliminates TB bacteria from infected tissues

A potential vaccine against tuberculosis has been found to completely eliminate tuberculosis bacteria from infected tissues in some mice. The vaccine was created with a strain of bacteria that, due to the absence of a few genes, are unable to avoid its host's first-line immune response.

5 Sep 2011

Researchers discover group of mutations involved in T-cell acute lymphoblastic leukemia

An international team of researchers has found a group of mutations involved in T-cell acute lymphoblastic leukemia (T-ALL), and showed that a group of certain drugs, already in clinical use to treat other diseases, can eliminate the cells carrying these mutations.

5 Sep 2011

Researchers discover new genetic defect that predisposes people to leukemia, myelodysplasia

A new genetic defect that predisposes people to acute myeloid leukemia and myelodysplasia has been discovered. The mutations were found in the GATA2 gene. Among its several regulatory roles, the gene acts as a master control during the transition of primitive blood-forming cells into white blood cells.

5 Sep 2011

Berlin to market wide range of Acino Pharma's current and future products in Thailand

Berlin Pharmaceutical Industry Co., Ltd. and Acino Pharma AG signed a long term partnership agreement under which Berlin will market a wide range of the Swiss company's current and future products in Thailand.

5 Sep 2011

Exposure to household smoke increases school absenteeism among children

Children who live in households where they are exposed to tobacco smoke miss more days of school than do children living in smoke-free homes, a new nationwide study confirms.

5 Sep 2011

Scientists identify human colon stem cells and grow them in lab-plates

Human colon stem cells have been identified and grown in a lab-plate for the first time. This achievement, made by researchers of the Colorectal Cancer Lab at the Institute for Research in Biomedicine and published in Nature Medicine, is a crucial advance towards regenerative medicine.

5 Sep 2011

Einstein researchers develop tuberculosis vaccine candidate

Researchers at Albert Einstein College of Medicine of Yeshiva University report in the September 4 online edition of Nature Medicine that they have developed a tuberculosis (TB) vaccine candidate that proved both potent and safe in animal studies.

5 Sep 2011

Study describes new class of anti-diabetic compound that targets unique molecular switch

In a joint study, scientists from The Scripps Research Institute and Harvard University's Dana-Farber Cancer Institute have established a new class of anti-diabetic compound that targets a unique molecular switch.

5 Sep 2011

Scientists sequence ten variants of E. coli O104:H4 outbreak strain across the world

Ten variants of the deadly Escherichia coli strain that hit Germany in May 2011 have been sequenced across the world. The unprecedented level of collaboration across the scientific community should give insight into how the outbreak arose, says a scientist at the Society for General Microbiology's Autumn Conference 2011.

5 Sep 2011

For 3 key GOP candidates, health care efforts show wide spectrum

The three most prominent current or former governors running for president - Rick Perry, Mitt Romney and Jon M. Huntsman Jr. - are firmly united in their commitment to repealing President Obama's health care law. But that unanimity masks a broad divergence in their approaches to the issue while in office, spanning the spectrum of Republican positioning.

5 Sep 2011

UNFPA Executive Director to visit refugee camps in Kenya on 3 September

Dr. Babatunde Osotimehin, Executive Director of UNFPA, the United Nations Population Fund, is visiting refugee camps in Kenya to underscore the urgent needs of women affected by the famine in the Horn of Africa.

3 Sep 2011

Radiologists should become knowledgeable with regard to meaningful use

Authors of a study in the September issue of the Journal of the American College of Radiology say, with an estimated $1.5 billion in potential bonus payments for radiology professionals at stake, radiologists should study and respond to recent federal regulations related to meaningful use of complete certified ambulatory electronic health records and their equivalents.

3 Sep 2011

Researchers help explain elusive mechanics of complex cell transport system

Every cell in the human body contains a complex system to transport essential cargoes such as proteins and membrane vesicles, from point A to point B. These tiny molecular motor proteins move at blistering speeds on miniature railways carrying components of the cell to their proper destinations.

3 Sep 2011

Scientists hope to create models that can more accurately predict spread of disease

Northwestern University professor Dirk Brockmann and his group at the McCormick School of Engineering and Applied Science have investigated the outcomes of a previously ignored mechanism in modeling how humans travel.

3 Sep 2011

Researchers discover mechanism of low-dose LDN on cell proliferative-related disorders

Researchers at The Pennsylvania State University College of Medicine, Hershey, Pennsylvania have discovered the mechanism by which a low dose of the opioid antagonist naltrexone (LDN), an agent used clinically to treat cancer and autoimmune diseases, exerts a profound inhibitory effect on cell proliferation.

3 Sep 2011

Child's homework motivation would improve if parents have more positive attitude

Parents who want to improve their child's motivation to complete homework this school year need to change their own attitude and behavior, according to a new study by Ben-Gurion University of the Negev (BGU) researchers.

3 Sep 2011

Medical News

Gilead to amend design of ongoing clinical trials against chronic hepatitis C

Teenagers use medicines frequently without receiving targeted information about risks and benefits

C. sporogenes bacterium could be used as vehicle to deliver drugs in frontline cancer therapy

Inflammation boosts activity of two proteins that can normalize blood sugar in diabetics

IKEPLUS immunization completely eliminates TB bacteria from infected tissues

Researchers discover group of mutations involved in T-cell acute lymphoblastic leukemia

Researchers discover new genetic defect that predisposes people to leukemia, myelodysplasia

Berlin to market wide range of Acino Pharma's current and future products in Thailand

Exposure to household smoke increases school absenteeism among children

Scientists identify human colon stem cells and grow them in lab-plates

Einstein researchers develop tuberculosis vaccine candidate

Study describes new class of anti-diabetic compound that targets unique molecular switch

Scientists sequence ten variants of E. coli O104:H4 outbreak strain across the world

For 3 key GOP candidates, health care efforts show wide spectrum

UNFPA Executive Director to visit refugee camps in Kenya on 3 September

Radiologists should become knowledgeable with regard to meaningful use

Researchers help explain elusive mechanics of complex cell transport system

Scientists hope to create models that can more accurately predict spread of disease

Researchers discover mechanism of low-dose LDN on cell proliferative-related disorders

Child's homework motivation would improve if parents have more positive attitude

Membrane proteins in focus: Turning high-risk targets into routine workflows

How metabolic phenotyping can detect viral infections in minutes

Directed enzyme evolution and the Nobel Prize: Making enzymes evolve in the lab

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