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Study demonstrates potential of nontoxic envelope proteins as an alternative to pseudotype lentiviral vectors

Therapeutic lentiviral vectors are emerging as vital tools for molecular medicine as evidenced by the growing number of clinical trials using these vector systems. From a basic research standpoint, lentiviral vectors are very intriguing substrates. On the one hand, the HIV-1 genome offers expanded cloning capacity and the capability to transduce nondividing cells such as hematopoietic stem cells (HSCs) and neurons.

4 Oct 2010

$3.4M grant for study to distinguish bacterial infections from viral infections in infants with fevers

Octavio Ramilo, MD, chief of Infectious Diseases at Nationwide Children's Hospital, is one of three principal investigators who will share in a five-year, $3.4 million grant from the Eunice Kennedy Shriver National Institute of Child Health and Human Development. Dr. Ramilo and a team of more than 50 physicians across the United States are investigating the use of novel technologies for distinguishing between bacterial and viral infections in infants with fevers within emergency departments.

4 Oct 2010

Mandatory contraceptive policy in clinical trials is excessive and can safely be relaxed

Research ethics review committees often require all women of childbearing age who enroll in clinical trials to use contraceptives to protect against a developing fetus being exposed to potentially harmful drugs. A mandatory contraceptive policy is often imposed even when there is no evidence that a trial drug could harm a fetus or when women have no chance of becoming pregnancy. This requirement is excessive and can safely be relaxed in many cases, according to a report in IRB: Ethics & Human Research.

4 Oct 2010

Benitec announces USPTO's reversal of all previous rejections in '099 Graham patent appeal

Benitec Limited, a leading Australian based company specialising in RNA interference (RNAi) technology is pleased to announce the United States Patent and Trademark Office's (USPTO) Board of Patent Appeals and Interferences decision ("the Decision") reversing all previous rejections in the US 6,573,099 (the '099 Graham patent) appeal.

4 Oct 2010

Cancer patients likely to experience memory impairment: Study

People with a history of cancer have a 40 percent greater likelihood of experiencing memory problems that interfere with daily functioning, compared with those who have not had cancer, according to results of a new, large study.

4 Oct 2010

Characteristics that help dialysis centers achieve higher patient survival rates

Characteristics such as patient engagement, physician communication, and staff coordination may help to explain why some dialysis centers achieve higher patient survival rates than others, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN).

4 Oct 2010

USDA NIFA awards $3.8M to develop healthier food products for humanitarian assistance programs

The USDA's National Institute of Food and Agriculture awarded nearly $3.8 million to develop healthier food products for humanitarian assistance programs.

4 Oct 2010

New quantitative methods to detect small signs of tremor

Sensitive new quantitive methods could be used to detect small signs of increased tremor and impaired motor skills caused by exposure to certain metals, and to follow up the treatment of neurological disorders, reveals a thesis from the University of Gothenburg, Sweden.

4 Oct 2010

Maven Semantic updates Urinary Incontinence research database

Maven Semantic announces updates to their Urinary Incontinence research database.

4 Oct 2010

UCI awarded $10M grant to explore ways of preventing staph infections in people harboring MRSA bacteria

A UC Irvine infectious disease specialist has received a three-year, $10 million grant to explore the effectiveness of new methods to prevent staph infections in people who harbor MRSA bacteria when they're discharged from the hospital.

4 Oct 2010

New report presents scientific data on environmental causes of breast cancer

A report released today by the Breast Cancer Fund presents a comprehensive summary of the scientific data on the environmental causes of breast cancer. The report catalogues the growing evidence linking breast cancer to synthetic hormones in pharmaceuticals, cosmetics and meat; pesticides in food; solvents in household cleaning products; BPA in food containers; flame retardants in furniture; and radiation from medical treatments.

4 Oct 2010

Single-incision, robot surgery at UT Southwestern helps fix congenital narrowing of ureters

A stabbing pain in Cameron Giammalva's abdomen came on so suddenly one day during his freshman year of college that he and his friends mistook it for appendicitis.

4 Oct 2010

Scientists discover c-Abl protein role in Parkinson's disease progression

Johns Hopkins scientists have discovered that the over-activation of a single protein may shut down the brain-protecting effects of a molecule and facilitate the most common form of Parkinson's disease.

4 Oct 2010

Welch Allyn launches Connex ProBP handheld automated digital blood pressure device

Welch Allyn, a leading global provider of frontline medical products and solutions, today introduced the Connex® ProBP™ 3400, an automated digital blood pressure device designed to fit in the palm of the hand. Borrowing Welch Allyn SureBP™ technology from the company's multiparameter vital signs devices, the Connex ProBP delivers fast, accurate blood pressure readings with the durability of Welch Allyn's popular hospital-grade vital signs devices.

4 Oct 2010

Researchers find new way to increase number of blood-forming stem cells when grown outside the body

One of the major challenges in stem cell transplants is how to obtain sufficient numbers of these remarkably rare cells to put into patients. To help overcome this issue, research from the Centenary Institute, Royal Prince Alfred Hospital and the University of Sydney has found a way to increase the number of blood-forming stem cells when growing them outside of the body.

4 Oct 2010

NIH announces T-R01 project award to examine human microbiome

The National Institutes of Health (NIH) announced today that Martin J. Blaser, MD, the Frederick H. King Professor of Internal Medicine at NYU Langone Medical Center has been awarded one of only twenty NIH Director's Transformative Research Projects (T-R01) award for research entitled "Disappearing Gastrointestinal Microbiota in Epidemic Obesity.

4 Oct 2010

Researchers identify ways to predict embryonic developmental success

Two-thirds of all human embryos fail to develop successfully. Now, in a new study, researchers at the Stanford University School of Medicine have shown that they can predict with 93 percent certainty which fertilized eggs will make it to a critical developmental milestone and which will stall and die. The findings are important to the understanding of the fundamentals of human development at the earliest stages, which have largely remained a mystery despite the attention given to human embryonic stem cell research.

4 Oct 2010

Researchers create new cell lines from mesenchymal stem cells

Biomedical researchers at the University at Buffalo have engineered adult stem cells that scientists can grow continuously in culture, a discovery that could speed development of cost-effective treatments for diseases including heart disease, diabetes, immune disorders and neurodegenerative diseases.

4 Oct 2010

Advances in treatment and management of neurological disorders

The latest advances in treating neurologic disorders such as stroke, headache, Parkinson's disease, epilepsy and sleep disorders are detailed in a special issue of the journal Neurologic Clinics.

4 Oct 2010

New edition of Sturge-Weber Syndrome textbook published

Eleven years after the first edition, a new edition of the Sturge-Weber Syndrome textbook has been published by the Sturge-Weber Foundation in New Jersey. Co-author E. Steve Roach, MD, is chief of Neurology and vice-chair of Pediatrics at Nationwide Children's Hospital.

4 Oct 2010

Medical News

Study demonstrates potential of nontoxic envelope proteins as an alternative to pseudotype lentiviral vectors

$3.4M grant for study to distinguish bacterial infections from viral infections in infants with fevers

Mandatory contraceptive policy in clinical trials is excessive and can safely be relaxed

Benitec announces USPTO's reversal of all previous rejections in '099 Graham patent appeal

Cancer patients likely to experience memory impairment: Study

Characteristics that help dialysis centers achieve higher patient survival rates

USDA NIFA awards $3.8M to develop healthier food products for humanitarian assistance programs

New quantitative methods to detect small signs of tremor

Maven Semantic updates Urinary Incontinence research database

UCI awarded $10M grant to explore ways of preventing staph infections in people harboring MRSA bacteria

New report presents scientific data on environmental causes of breast cancer

Single-incision, robot surgery at UT Southwestern helps fix congenital narrowing of ureters

Scientists discover c-Abl protein role in Parkinson's disease progression

Welch Allyn launches Connex ProBP handheld automated digital blood pressure device

Researchers find new way to increase number of blood-forming stem cells when grown outside the body

NIH announces T-R01 project award to examine human microbiome

Researchers identify ways to predict embryonic developmental success

Researchers create new cell lines from mesenchymal stem cells

Advances in treatment and management of neurological disorders

New edition of Sturge-Weber Syndrome textbook published

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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