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ArQule, Daiichi Sankyo present positive data from Phase 2 combination ARQ 197 trial for lung cancer at ASCO

ArQule, Inc. and Daiichi Sankyo Co., Ltd. today announced the presentation of data from a Phase 2 clinical trial at the 2010 Annual Meeting of the American Society of Clinical Oncology (ASCO) showing encouraging overall survival (OS) results with ARQ 197 in combination with erlotinib among patients with advanced, refractory non-small cell lung cancer.

7 Jun 2010

Sexsomnia more common in men than women

Sexsomnia was reported by almost eight percent of patients at a sleep disorders center and was more common in men than women, according to a research abstract that will be presented Monday, June 7, 2010, in San Antonio, Texas, at SLEEP 2010, the 24th annual meeting of the Associated Professional Sleep Societies LLC.

7 Jun 2010

ZymoGenetics' IL-21 Phase 2 clinical trial in metastatic melanoma meets primary endpoint

ZymoGenetics, Inc. today announced positive results from a Phase 2 clinical trial in metastatic melanoma with recombinant Interleukin 21 (IL-21) as a single agent. The trial met the primary endpoint of efficacy, as measured by objective response rate or lack of early disease progression. Overall response rate was 23.1%, in evaluable patients, and median progression-free survival was 4.3 months. The results were presented at the American Society of Clinical Oncology meeting.

7 Jun 2010

Humana sees strong future in Medicare; AHIP seeks more cost containment measures

The Louisville Courier Journal: "While private Medicare Advantage plans face funding pressure from Washington, Medicare 'is actually a very good place to be,' the chief executive of Louisville-based Humana said. 'The federal government "can be relied upon to pay their bills," Michael McCallister said at the Bernstein Strategic Decisions investor conference. 'Medicare is going to be a very big business in the future'"(6/5).

7 Jun 2010

Celldex Therapeutics reports mature data from CDX-011 Phase 1/2 study in advanced breast cancer

Celldex Therapeutics, Inc. today announced that mature results from a Phase 1/2 study evaluating CDX-011 in advanced stage breast cancer patients were presented at the 46th Annual Meeting of the American Society of Clinical Oncology (ASCO). CDX-011 is an experimental antibody-drug conjugate (ADC) directed against glycoprotein NMB (GPNMB) and linked to a potent cancer cell-killing drug, monomethyl-auristatin E (MMAE).

7 Jun 2010

Chronic insomnia increases mortality risk

Individuals with chronic insomnia have an elevated risk of death, according to a research abstract that will be presented Monday, June 7, 2010, in San Antonio, Texas, at SLEEP 2010, the 24th annual meeting of the Associated Professional Sleep Societies LLC.

7 Jun 2010

Positive phase III clinical trial data of NovoCure's NovoTTF device for recurrent GBM presented at ASCO

Data from the first phase III clinical trial of NovoCure's NovoTTF device for treatment of patients with recurrent glioblastoma (GBM) were presented today as a late breaking abstract during the Neuro-Oncology session at the American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago. Study results show that NovoTTF, a novel, non-invasive, portable medical device, may be as or more effective than the best available chemotherapies for GBM, but without the toxicity usually associated with cytotoxic or targeted treatments.

7 Jun 2010

Health overhaul supporters plan $25 million promotion campaign

The New York Times: "Close allies of the Obama administration, seeking to rally the public behind President Obama's landmark health care bill, are planning to spend $25 million over the next five years to promote the measure and beat back mischaracterizations of it that could harm Democratic candidates. Mr. Obama's former communications director, Anita Dunn, and longtime Democratic strategist Andrew Grossman, have teamed up to form two new tax-exempt groups.

7 Jun 2010

Hunger-signaling hormone ghrelin regulates circulation of cholesterol in brain

Circulation of cholesterol is regulated in the brain by the hunger-signaling hormone ghrelin, researchers say. The finding points to a new potential target for the pharmacologic control of cholesterol levels.

7 Jun 2010

Alder Biopharmaceuticals reports positive data from ALD518 Phase 2a clinical trial for NSCLC

Alder Biopharmaceuticals Inc. today announced that patients with late-stage non-small cell lung cancer (NSCLC) showed improvement in cancer-related anemia and symptoms of the disease in a Phase 2a clinical trial of ALD518, a monoclonal antibody directed against interleukin-6 (IL-6).

7 Jun 2010

Phase Ib/II trial data for trastuzumab-DM1 in combination with pertuzumab presented at ASCO 2010

ImmunoGen, Inc., a biopharmaceutical company that develops targeted anticancer therapeutics, today announced the presentation of clinical data from a Phase Ib/II trial conducted by Roche and Genentech to investigate the safety and preliminary efficacy of trastuzumab-DM1 (T-DM1) used in combination with Roche's investigational antibody, pertuzumab.

7 Jun 2010

Congress returns to controversy over COBRA, doctors' Medicare pay

CongressDaily reports that when members of Congress return to Washington Monday "they face a raft of unfinished business on tax 'extender' legislation. … The Senate will look to take up a $114.5 billion package of unemployment benefits, tax breaks, physician payments and other provisions this week amid calls from the right to scale it back, from the left to expand it and from businesses to mitigate its tax increases.

7 Jun 2010

ChemGenex reports positive safety findings from two OMAPRO clinical trials at ASCO 2010

ChemGenex Pharmaceuticals Limited announced that positive safety findings from a combined analysis of two clinical trials for its lead product candidate, OMAPRO™ (omacetaxine mepesuccinate), were presented today during a poster discussion session at the 2010 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago, Illinois.

7 Jun 2010

Expansion of e-mental health necessary for better care

Assistance for mental ailments especially in the youth via internet could be a very cost effective measure say researchers. The researchers have identified the gaps between the demand and supply of mental healthcare services in Australia.

6 Jun 2010

WA health budget can afford the wigs for cancer patients again

The West Australian government has withdrawn funds allotted for wigs for cancer patients at Sir Charles Gairdner Hospital. Cancer patients typically lose their hair during therapy. The measure was undertaken to cut costs and has been severely criticized by the opposition.

6 Jun 2010

Bowel cancer affecting more and more Australians

Bowel cancer or colon cancer was till now considered a disease that affected elderly men. Recent trends however show that it is affecting more and more Australians in a younger age group.

6 Jun 2010

Scientists make water-free liquid from blood protein

Scientists at the University of Bristol have discovered a way to make a highly concentrated water-free liquid of a key blood protein, myoglobin, opening up the possibility of new types of biomedical materials.

6 Jun 2010

Positive results from new analyses of denosumab Phase 3 trials

Amgen today announced positive results from several new analyses of two Phase 3 trials studying denosumab compared with Zometa® (zoledronic acid), the current standard of care, for the treatment of bone metastases in patients with advanced breast cancer ("136 study") and solid tumors or multiple myeloma ("244 study"). Results from these trials reinforce denosumab's consistent ability to delay the complications of bone metastases in patients with advanced cancer. These results are being presented during the 2010 American Society of Clinical Oncology Annual Meeting in Chicago.

5 Jun 2010

Decline in populations of endangered fish species at Ash Meadows

Every minute, 10,000 gallons of water mysteriously gush out of the desert floor at a place called Ash Meadows, an oasis that is home to 24 plant and animal species found nowhere else in the world.

5 Jun 2010

New symbiotic starter culture investigated for production of original yogurt

Yogurt production is traditional branch in our food industry. Yogurt is a fermented milk product that contains the characteristic bacterial cultures Lactobacillus bulgaricus and Streptococcus thermophilus. One of them is invented and used for the first time in our country and that's why it is named after Bulgaria.

5 Jun 2010

Medical News

ArQule, Daiichi Sankyo present positive data from Phase 2 combination ARQ 197 trial for lung cancer at ASCO

Sexsomnia more common in men than women

ZymoGenetics' IL-21 Phase 2 clinical trial in metastatic melanoma meets primary endpoint

Humana sees strong future in Medicare; AHIP seeks more cost containment measures

Celldex Therapeutics reports mature data from CDX-011 Phase 1/2 study in advanced breast cancer

Chronic insomnia increases mortality risk

Positive phase III clinical trial data of NovoCure's NovoTTF device for recurrent GBM presented at ASCO

Health overhaul supporters plan $25 million promotion campaign

Hunger-signaling hormone ghrelin regulates circulation of cholesterol in brain

Alder Biopharmaceuticals reports positive data from ALD518 Phase 2a clinical trial for NSCLC

Phase Ib/II trial data for trastuzumab-DM1 in combination with pertuzumab presented at ASCO 2010

Congress returns to controversy over COBRA, doctors' Medicare pay

ChemGenex reports positive safety findings from two OMAPRO clinical trials at ASCO 2010

Expansion of e-mental health necessary for better care

WA health budget can afford the wigs for cancer patients again

Bowel cancer affecting more and more Australians

Scientists make water-free liquid from blood protein

Positive results from new analyses of denosumab Phase 3 trials

Decline in populations of endangered fish species at Ash Meadows

New symbiotic starter culture investigated for production of original yogurt

Synthetic Biology and the Pursuit of Living Diagnostics

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

Shaping the future of lab automation through AI and robotics

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