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USP announces revision schedule for Model Guidelines Version 5.0

As the Medicare Model Guidelines-a listing of therapeutic categories and pharmacologic classes that Medicare Part D plans can utilize when developing their formularies-undergo revision for the first time in three years, the U.S. Pharmacopeial Convention (USP) is announcing its revision schedule and the expanded opportunities for public input as it develops Version 5.0.

6 Oct 2010

Amino acid mixture increases survival in mice

When mice are given drinking water laced with a special concoction of amino acids, they live longer than your average mouse, according to a new report in the October issue of Cell Metabolism, a Cell Press publication. The key ingredients in the supplemental mixture are so-called branched-chain amino acids, which account for 3 of the 20 amino acids (specifically leucine, isoleucine, and valine) that are the building blocks of proteins.

6 Oct 2010

Accountable Care Organizations trigger legal worries from health care providers and insurers

Kaiser Health News staff writers Jenny Gold and Phil Galewitz report: "Doctors and hospitals eager to pursue a new model of health care being promoted by the Obama administration are raising concerns that they could run afoul of antitrust and anti-fraud laws, while insurers are warning that the new arrangements could lead to higher prices for medical care" (Gold and Galewitz, 10/5).

6 Oct 2010

ADRCs cells improve survival in acute kidney injury animal model

Preclinical data was published today on research performed by Cytori Therapeutics (NASDAQ:CYTX) showing adipose (fat)-derived stem and regenerative cells (ADRCs), either fresh or banked, demonstrated statistically significant improvements in animal survival and kidney function in an acute kidney injury animal model.

6 Oct 2010

Profectus BioSciences awarded $3.1M Fast Track SBIR grant to develop prophylactic vaccine against HIV

Profectus BioSciences, Inc., a technology based vaccine company devoted to the treatment and prevention of chronic viral diseases, today announced the award of a Fast Track SBIR from the Division of AIDS, National Institutes of Health for $3.1M to support the development of the Company's Transition State Vaccine (TSV) technology for a prophylactic HIV Vaccine.

6 Oct 2010

IDMC recommends early termination of Phase 3 intramuscular depot aripiprazole trial

Otsuka Pharmaceutical Co., Ltd. (OPC) and Otsuka Pharmaceutical Development & Commercialization, Inc. (OPDC) announced today that an independent data monitoring committee (IDMC) has recommended the early termination of its Phase 3, 52-week, placebo-controlled, intramuscular depot aripiprazole trial.

6 Oct 2010

Fish oil induces severe colitis and colon cancer in mice

Fish oil - long encouraged by doctors as a supplement to support heart and joint health, among other benefits - induced severe colitis and colon cancer in mice in research led by Michigan State University and published this month in the journal Cancer Research.

6 Oct 2010

Sebelius: Medicare Advantage cuts won't hurt plans

Will the health law curb private Medicare insurance plans, known as Medicare Advantage, or won't it? Health and Human Services Secretary Kathleen Sebelius told reporters Monday that it won't, the Pittsburgh Post-Gazette reports. "Ms. Sebelius said the decision by a large Massachusetts insurer to leave the Medicare Advantage market is not a harbinger of the program's decline.

6 Oct 2010

Medtronic launches new KYPHON Express Curette for scraping or scoring bone in the spine

Medtronic Inc. today announced the launch of the new KYPHON® Express™ Curette for scraping or scoring bone in the spine, including during treatment of vertebral compression fractures with minimally invasive KYPHON® Balloon Kyphoplasty.

6 Oct 2010

Researchers find exposure to air pollution increases severity of asthma symptoms

Exposure to dirty air is linked to decreased function of a gene that appears to increase the severity of asthma in children, according to a joint study by researchers at Stanford University and the University of California, Berkeley.

6 Oct 2010

Cancer cells utilize energy-rich intermediates of sugar metabolism: Research

Cancer research is facing a radical change of direction. Cancer cells do not obtain their energy from the breakdown of sugar to carbon dioxide and water, but from energy-rich intermediates of sugar metabolism instead.

6 Oct 2010

Today's OpEds: ACOs, Health care honesty and the sanctity of health insurance

This year, some workers might see a new acronym in the alphabet soup of HMOs and PPOs. This one is called ACO, and it might be just the thing our health care system needs (Dr. Paul Grundy, 10/5).

6 Oct 2010

Researchers develop new method to assess stress vulnerability

An impressive body of knowledge has linked stress to illness vulnerability. Yet stress is inextricably linked to everyday life. A group of researchers of the University of Bologna headed by Prof. Giovanni Fava has developed a new method for assessing it that is described in the current issue of Psychotherapy and Psychosomatics.

6 Oct 2010

Novel invasive surgery for children with scoliosis may eliminate need for spinal fusion

A novel minimally invasive surgery for young children living with a difficult-to-treat progressive form of scoliosis, known as juvenile idiopathic scoliosis, may eliminate the need for spinal fusion later in adolescence, according to new research by surgeons from Children's Mercy Hospitals and Clinics in Kansas City, Mo. The study was presented at the American Academy of Pediatrics National Conference and Exhibition in San Francisco.

6 Oct 2010

Weight loss success linked to amount of sleep: Study

A new study released Tuesday in the Annals of Internal Medicine suggests that sleeping may help one to lose fat. The study compared two groups of people who were trying to lose weight. One group was assigned to sleep 5.5 hours each night for two weeks, while the other was able to sleep 8.5 hours. The scientists found that the sleep deprived people had higher levels of ghrelin. It may be this hormone that drives appetite that leads to excess eating, believe researchers.

6 Oct 2010

Altravax receives two SBIR grants for antibody-inducing vaccines research on HIV-1

Altravax, Inc. announced today that it has been awarded two SBIR grants totaling $1.2 million from the NIH's National Institute of Allergy and Infectious Diseases for research on antibody-inducing vaccines for HIV-1.

6 Oct 2010

New approach method could simplify study and treatment of human diseases

Therapeutic antibodies can be an efficient alternative when common drugs do not work anymore. However, antibodies obtained from blood of animals such as mice could not be used: The human immune system recognizes them as foreign and rejects them.

6 Oct 2010

Lixte, NCI collaborate for clinical evaluation of LB-100 compound

Lixte Biotechnology Holdings announced today that the National Cancer Institute Experimental Therapeutics (NExT) Program Senior Advisory Committee (SAC), Division of Cancer Treatment and Diagnosis (DCTD), National Cancer Institute (NCI), National Institutes of Health (NIH), signed a NExT Material Transfer Agreement formalizing a collaboration with Lixte Biotechnology Holdings, Inc. for clinical evaluation of LB-100, one of Lixte's lead anti-cancer compounds.

6 Oct 2010

Knome announces winners of KnomeDISCOVERY Awards

Knome, Inc. today announced the winners of its inaugural KnomeDISCOVERY Awards, a program designed to spur new genetic insights into health.

6 Oct 2010

Isogenica, NovaBiotics to accelerate the development of peptide anti-infective technology

Isogenica Ltd, today announced that it has entered into a collaboration agreement with NovaBiotics, a leading clinical-stage biotechnology company to fast-track the development of NovaBiotic's platform peptide anti-infective technology.

6 Oct 2010

Medical News

USP announces revision schedule for Model Guidelines Version 5.0

Amino acid mixture increases survival in mice

Accountable Care Organizations trigger legal worries from health care providers and insurers

ADRCs cells improve survival in acute kidney injury animal model

Profectus BioSciences awarded $3.1M Fast Track SBIR grant to develop prophylactic vaccine against HIV

IDMC recommends early termination of Phase 3 intramuscular depot aripiprazole trial

Fish oil induces severe colitis and colon cancer in mice

Sebelius: Medicare Advantage cuts won't hurt plans

Medtronic launches new KYPHON Express Curette for scraping or scoring bone in the spine

Researchers find exposure to air pollution increases severity of asthma symptoms

Cancer cells utilize energy-rich intermediates of sugar metabolism: Research

Today's OpEds: ACOs, Health care honesty and the sanctity of health insurance

Researchers develop new method to assess stress vulnerability

Novel invasive surgery for children with scoliosis may eliminate need for spinal fusion

Weight loss success linked to amount of sleep: Study

Altravax receives two SBIR grants for antibody-inducing vaccines research on HIV-1

New approach method could simplify study and treatment of human diseases

Lixte, NCI collaborate for clinical evaluation of LB-100 compound

Knome announces winners of KnomeDISCOVERY Awards

Isogenica, NovaBiotics to accelerate the development of peptide anti-infective technology

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

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