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The epigenetic alterations of monocytes in severe COVID-19

Researchers performed DNA methylation analysis on monocytes in the peripheral blood samples obtained from severe COVID-19 patients.

28 Oct 2022

When monkeypox reaches rural communities, it collides with strained public health systems

When a case of monkeypox was reported in Nevada's Humboldt County in August, it was the state's first detected occurrence of the virus in a rural area. Soon, cases were found in other rural counties — Nye, Lyon, and Elko — posing another hurdle for public health systems that have been worn thin by the covid-19 pandemic.

28 Oct 2022

Association of COVID-19 severity with nasopharyngeal fungal colonization and interleukin-17 induction

Researchers evaluated the concurrent colonization of fungi in the nasopharynx of severe COVID-19 patients.

28 Oct 2022

The dynamics of COVID-19 conspiracist ideation

Researchers studied the dynamics of COVID-19 conspiracist ideation—a general tendency to believe in conspiracy theories.

28 Oct 2022

Overall cancer death rates continue to decline in the United States, says Annual Report to the Nation

Overall cancer death rates continued to decline among men, women, children, and adolescents and young adults in every major racial and ethnic group in the United States from 2015 to 2019, according to the latest Annual Report to the Nation on the Status of Cancer. From 2014 to 2018, overall cancer incidence, or new cases of cancer, remained stable for men and children but increased for women and adolescents and young adults.

28 Oct 2022

AI models improve the accuracy of diagnosing coronary artery disease

Several recent discoveries show that the accuracy of diagnosing coronary artery disease and predicting patient risk is improved with the help of artificial intelligence (AI) models developed by scientists in the Division of Artificial Intelligence in Medicine at Cedars-Sinai.

28 Oct 2022

Research reveals a differential clinical response to pembrolizumab in uterine cancer patients

New research from Yale Cancer Center reveals for the first time ever a differential clinical response to pembrolizumab in Lynch-like (mutated) vs methylated microsatellite instability-high (MSI-H) uterine cancer patients, increasing our understanding about the proportion of patients that derive benefit from immune checkpoint blockade.

28 Oct 2022

New breakthrough in understanding how deletion of certain genes can lead to cancer growth

Genetic mutations kick start cancers. Some mutations shuffle the genetic code, others come from the deletion of key genes.

28 Oct 2022

ADOS testing not required for ASD diagnosis by developmental-behavioral pediatricians

Trained developmental-behavioral pediatricians can generally diagnose autism spectrum disorder (ASD) in young children without the need for additional Autism Diagnostic Observation Schedule (ADOS) testing, finds a prospective multicenter study.

28 Oct 2022

Low-density granulocytes are phenotypically altered in people with long-COVID

In a recent study posted to the bioRxiv* preprint server, researchers characterized low-density granulocyte (LDG) neutrophil (NP) proportion among individuals up to 14 months post-SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) infection.

28 Oct 2022

Scientists computationally restore the potency of an antibody against SARS-CoV-2 Omicron subvariants

A team of researchers from the United States computationally modified the COV2-2130 monoclonal antibody to restore its neutralizing ability against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron subvariants, while retaining efficacy against the Delta and wild-type strains.

27 Oct 2022

Commensal gut microbes from IBD patients produce genotoxic metabolites

Functional screening of human gut microbiota reveals a family of small molecule genotoxins called indolimines in patients with inflammatory bowel disease (IBD), according to a new study.

27 Oct 2022

Combination of multi-specificity and antibody avidity enhances protection against SARS-CoV-2

In a recent study posted to the bioRxiv* preprint server, an international team of researchers leveraged the human light chain apoferritin protomer-derived MULTI-specific, multi-Affinity antibody (Multabody, MB) platform for the generation of broad and potent SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2)-neutralizing antibodies (Abs).

27 Oct 2022

Rutgers physicians take newer approach in successfully treating a mysterious disease

The prognosis for the sick child, who hadn't responded to standard treatment, was dire. But a team of Rutgers physicians believed there might be hope despite the conventional wisdom against pursuing any further treatment.

27 Oct 2022

Researchers use CRISPR-edited T cells to treat seriously ill children with resistant leukaemia

Researchers at Great Ormond Street Hospital for Children (GOSH) and UCL Great Ormond Street Institute of Child Health (UCL GOS ICH) have used CRISPR/Cas9 technology to engineer donor T cells to try to treat seriously ill children with resistant leukaemia, who had otherwise exhausted all available therapies.

27 Oct 2022

Newly developed chemical compounds show promise as potential anticancer therapy

A University of Kentucky Markey Cancer Center researcher's team developed new chemical compounds that show promise as a potential anticancer therapy to treat aggressive tumors.

27 Oct 2022

Updapted BA.4/5 COVID vaccines boost protection but might not surpass original formula

In a recent study posted to the bioRxiv* preprint server, researchers at Beth Israel Deaconess Medical Center assessed the immunogenicity associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) BA.5 bivalent messenger ribonucleic acid (mRNA) vaccine boosters.

27 Oct 2022

An unprecedented list of health-threatening fungi released by the WHO

The WHO fungal priority pathogens list ranks pathogens that pose a serious risk of morbidity and mortality in humans.

27 Oct 2022

New report highlights the health impacts of air pollution in Africa

Nearly all the African continent faces some of the most severe health impacts in the world caused by air pollution, with several countries experiencing some of the highest levels of air pollution in the world, according to a new report published by the U.S.-based research organization Health Effects Institute.

27 Oct 2022

New initiative to improve post-acute stroke care across Montana, Nebraska and North Dakota

The American Heart Association, the world's leading voluntary organization focused on heart and brain health for all, is launching a two-year initiative to expand and enhance post-acute stroke care across Montana, Nebraska and North Dakota, giving all patients the best chance at independent life after stroke.

27 Oct 2022

Medical News

The epigenetic alterations of monocytes in severe COVID-19

When monkeypox reaches rural communities, it collides with strained public health systems

Association of COVID-19 severity with nasopharyngeal fungal colonization and interleukin-17 induction

The dynamics of COVID-19 conspiracist ideation

Overall cancer death rates continue to decline in the United States, says Annual Report to the Nation

AI models improve the accuracy of diagnosing coronary artery disease

Research reveals a differential clinical response to pembrolizumab in uterine cancer patients

New breakthrough in understanding how deletion of certain genes can lead to cancer growth

ADOS testing not required for ASD diagnosis by developmental-behavioral pediatricians

Low-density granulocytes are phenotypically altered in people with long-COVID

Scientists computationally restore the potency of an antibody against SARS-CoV-2 Omicron subvariants

Commensal gut microbes from IBD patients produce genotoxic metabolites

Combination of multi-specificity and antibody avidity enhances protection against SARS-CoV-2

Rutgers physicians take newer approach in successfully treating a mysterious disease

Researchers use CRISPR-edited T cells to treat seriously ill children with resistant leukaemia

Newly developed chemical compounds show promise as potential anticancer therapy

Updapted BA.4/5 COVID vaccines boost protection but might not surpass original formula

An unprecedented list of health-threatening fungi released by the WHO

New report highlights the health impacts of air pollution in Africa

New initiative to improve post-acute stroke care across Montana, Nebraska and North Dakota

Advancing Menopause Care: Non-Hormonal Treatments for Vasomotor Symptoms

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

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