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Research reveals why a common genetic variant worsens outcomes for people with ALS and FTD

A pioneering new study led by UCL and National Institutes of Health (NIH) scientists has revealed, for the first time, why a common genetic variant worsens disease outcomes for people with the devastating adult-onset neurodegenerative diseases amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).

24 Feb 2022

Study examines the effect of sevoflurane on sleep disturbance caused by systemic inflammation

Getting a good night's sleep can sometimes be a challenge, but inflammation may make it even more difficult.

24 Feb 2022

Immune responses in patients with varying degrees of SARS-CoV-2 infection

In a recent research article published in the journal PLoS ONE, researchers looked at immunological responses in relation to established risk factors for serious illness. This prospective cohort study reports on long-lasting SARS-CoV-2 specific antibody and T-cellular immune responses six months after infection in rt-PCR confirmed cases of different illness severity (community and hospitalized patients).

24 Feb 2022

Edible egg-derived IgY antibodies against SARS-CoV-2 Omicron

A new study posted to the bioRxiv* preprint server reports on the development of anti-RBD immunoglobulin Y (IgY) antibodies from chicken eggs to block the binding of the viral RBD to human ACE2 receptors. This approach has several advantages since chicken egg-derived IgY can be edible and polyclonal can target multiple epitopes, enhancing neutralizing activity.

23 Feb 2022

Scientists discover how a rare genetic disorder disrupts key neural interactions in the developing brain

Every time you chew, talk, yawn, or sense the zap of a toothache, cranial nerve cells are shuttling electrochemical signals to your brain.

23 Feb 2022

First reported case of a cat infected with SARS-CoV-2 Delta AY.3 variant

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is hurting our loved ones — even those that walk on four legs. Researchers from the University of Pennsylvania documented the recovery of an 11-year old indoor housecat living in Delaware who first presented to the veterinary hospital after experiencing distressing gastrointestinal symptoms.

23 Feb 2022

Abdominal obesity may lead to greater risk of COPD and asthma in women

Obesity has been linked to a wide array of health problems. A new study suggests that abdominal obesity as measured by body mass index (BMI) and waist circumference, may result in a greater risk of chronic obstructive pulmonary disease (COPD) and asthma.

23 Feb 2022

New studies explore the potential role of bariatric surgery in reducing breast cancer risk

New studies aim to clarify the relationship between obesity and breast cancer, and explore the potential role of bariatric surgery in reducing this risk, according to a review published online in Obesity, The Obesity Society's flagship journal.

23 Feb 2022

Research shows the importance of stopping drug use in early adulthood

Young people who use drugs but quit before adulthood are – on average – not harming their future life chances, according to new research which tracked thousands of people over a 16-year period.

23 Feb 2022

Study on Omicron related mortality in cancer patients during recent COVID wave

A recent pre-proof study published in the journal Cancer Cell assessed the CFR of cancer patients during the third wave of the coronavirus disease 2019 (COVID-19) pandemic caused by the SARS-CoV-2 Omicron variant.

23 Feb 2022

Researchers explore possible use of stress reduction in atrial fibrillation management

Stress has been linked with poor health outcomes, though the exact mechanism remains poorly defined. Psychological stress is recognized as a contributing factor in atrial fibrillation (AFib), both in initiation and heightening of AFib.

23 Feb 2022

Tiny lipid-based nanoparticles carry genetic instructions directly into the lungs

Researchers at the Tufts University School of Engineering are building a reputation for precision targeting in drug delivery.

23 Feb 2022

Discovery of signaling pathway in immune cells may lead to new therapeutic approach for autoimmune diseases

Autoimmune diseases are triggered when the immune system malfunctions and attacks the body's own structures.

23 Feb 2022

Neanderthal gene makes people susceptible to COVID-19, but protects against HIV

A study recently published in the top-tier journal Proceedings of the National Academy of Sciences of the United States of America (PNAS) shows how a specific gene flow from Neandertals can act as a double-edged sword by increasing the risk for the development of severe coronavirus disease 2019 (COVID-19), and at the same time decreasing the risk for the infection with the human immunodeficiency virus (HIV).

23 Feb 2022

Firearms surpass car crashes as the leading cause of premature traumatic deaths in the U.S.

Firearms have overtaken car crashes as the main cause of premature deaths due to trauma in the US since 2017, finds research published online in the journal Trauma Surgery & Acute Care Open.

23 Feb 2022

Nearly 1% of all US adults prescribed opioids are also taking various other sedatives

As many as 2.6 million Americans—equivalent to 1 per cent of all US adults —prescribed opioids are also taking various other sedatives, including benzodiazepines plus another type of sedative drug, estimates research published online in the journal Regional Anesthesia & Pain Medicine.

23 Feb 2022

Periconceptional maternal smoking associated with delay in embryonic development

Smoking by mothers during the period immediately before and after conception is linked to a delay in embryonic development, smaller foetuses at the time of the 20-week ultrasound scan, and lower birth weight.

23 Feb 2022

Study shows positive effects of growing up with a sibling with disabilities

Having a child with a disability or a developmental delay is often a stressful experience for a family. Siblings in such families may be exposed to greater stress and challenges.

23 Feb 2022

Artificially intelligent olfactory system may diagnose Parkinson’s disease at an early stage

A couple of years ago, a woman named Joy Milne made headlines when scientists discovered that she could "smell" Parkinson's disease (PD) on people with the neurodegenerative disorder.

23 Feb 2022

Cell stress-related biochemical events may be partly driving Parkinson's disease

Parkinson's disease may be driven in part by cell stress-related biochemical events that disrupt a key cellular cleanup system, leading to the spread of harmful protein aggregates in the brain, according to a new study from scientists at Scripps Research.

23 Feb 2022

Medical News

Research reveals why a common genetic variant worsens outcomes for people with ALS and FTD

Study examines the effect of sevoflurane on sleep disturbance caused by systemic inflammation

Immune responses in patients with varying degrees of SARS-CoV-2 infection

Edible egg-derived IgY antibodies against SARS-CoV-2 Omicron

Scientists discover how a rare genetic disorder disrupts key neural interactions in the developing brain

First reported case of a cat infected with SARS-CoV-2 Delta AY.3 variant

Abdominal obesity may lead to greater risk of COPD and asthma in women

New studies explore the potential role of bariatric surgery in reducing breast cancer risk

Research shows the importance of stopping drug use in early adulthood

Study on Omicron related mortality in cancer patients during recent COVID wave

Researchers explore possible use of stress reduction in atrial fibrillation management

Tiny lipid-based nanoparticles carry genetic instructions directly into the lungs

Discovery of signaling pathway in immune cells may lead to new therapeutic approach for autoimmune diseases

Neanderthal gene makes people susceptible to COVID-19, but protects against HIV

Firearms surpass car crashes as the leading cause of premature traumatic deaths in the U.S.

Nearly 1% of all US adults prescribed opioids are also taking various other sedatives

Periconceptional maternal smoking associated with delay in embryonic development

Study shows positive effects of growing up with a sibling with disabilities

Artificially intelligent olfactory system may diagnose Parkinson’s disease at an early stage

Cell stress-related biochemical events may be partly driving Parkinson's disease

How Programmable Nanobiology Could Drive the Fifth Industrial Revolution

Dr. Anthony Grice

Building quality into drug development for safer, faster medicines

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