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Clinical trial results do not support the use of fish oil supplements to prevent depression

Results from the largest clinical trial of its kind do not support the use of fish oil supplements - a source of omega-3 fatty acid - to help prevent depression.

21 Dec 2021

Alternative statistical method can make clinical trials more reliable and trustworthy

An alternative statistical method honed and advanced by Cornell researchers can make clinical trials more reliable and trustworthy while also helping to remedy what has been called a "replicability crisis" in the scientific community.

21 Dec 2021

Simple, inexpensive method to predict the risk of functional disability in older people

Researchers at the Federal University of São Carlos in the state of São Paulo, Brazil, in partnership with colleagues at University College London in the UK have discovered an efficient, simple and inexpensive method of predicting the risk of functional disability in older people.

21 Dec 2021

National U.S trial confirms effectiveness of mRNA COVID-19 vaccines

In a recent study, published in the Annals of Internal Medicine, scientists conducted a target trial emulation study and documented that among the elderly in the U.S. (with significant comorbidities), the efficacy of messenger RNA (mRNA) vaccines was much lower in terms of preventing infection, than previously reported. However, the effectiveness against death was found to be high.

21 Dec 2021

Proportion of ‘frequent attenders’ has risen over the past two decades, study reveals

'Frequent attenders' now make up around 4 in every 10 family doctor (GP) consultations in England, and the proportion of such patients has risen over the past two decades, reveals a large long term study published in the open access journal BMJ Open.

21 Dec 2021

Doctors advised to prescribe fewer antidepressants and for shorter periods of time

Doctors should prescribe fewer antidepressants and for shorter periods of time, because of the ongoing uncertainties about their effectiveness and the potential severity and durability of the withdrawal symptoms associated with them, suggests a review of the evidence on antidepressant use, published online in the Drug and Therapeutics Bulletin.

21 Dec 2021

Promising new drug target for TB identified

Mycobacterium tuberculosis (Mtb), the hardy bacterial species that causes tuberculosis (TB), has an unexpected vulnerability that future drugs may be able to exploit, according to a study from researchers at Weill Cornell Medicine.

21 Dec 2021

3D-printed tracheal replacement splint offers hope for treating rare developmental abnormality

Ramiah Martin isn't like other little girls, and that's perfectly fine with her mother. "She is nothing short of a miracle," Leanne Martin said of her daughter, who was facing long odds before her birth in December 2017, after being diagnosed with heart problems during a prenatal ultrasound.

21 Dec 2021

Comparison of SARS-CoV-2 rapid antigen tests

Researchers test commercially rapid antigen tests to evaluate their analytical sensitivity and specificity, as well as clinical sensitivity for detecting SARS-CoV-2.

21 Dec 2021

Early administration of SARS-CoV-2 convalescent plasma reduces outpatient hospitalizations

The results of a nationwide, multicenter clinical trial led by Johns Hopkins Medicine and the Johns Hopkins Bloomberg School of Public Health provides solid evidence for the use of plasma from convalescent patients — those who have recovered from the disease and whose blood contains antibodies against SARS-CoV-2, the virus that causes COVID-19 — as an early treatment.

21 Dec 2021

Risk of exposure to SARS-CoV-2 by workplace and trade

Researchers investigate the risk of SARS-CoV-2 exposure to people in workplaces across different occupations over time.

21 Dec 2021

FDA approval of long-acting injectable drug marks a vital expansion of HIV prevention options

Yesterday the U.S. Food and Drug Administration announced its first approval of a long-acting HIV prevention medication. Developed by ViiV Healthcare, the medicine is long-acting cabotegravir injected once every two months.

21 Dec 2021

How the SARS-CoV-2 Omicron variant spike protein is changing

The study assesses the degree to which the D614G mutation in the SARS-CoV-2 RBD allows access of spike protein trimers to LA-binding-like conformations.

21 Dec 2021

Comparison of point-of-care SARS-CoV-2 diagnostic kits

A multinational group of scientists investigates the performance characteristics of several point-of-care diagnostic kits for SARS-CoV-2.

21 Dec 2021

What are the long-term effects of COVID-19 on mental health?

Researchers determine the long-term adverse mental health symptoms associated with COVID-19 by estimating acute infection severity.

21 Dec 2021

UK research investigates relationship between COVID-19 vaccination and Guillain-Barré syndrome

Researchers investigate the possible relationship between COVID-19 vaccination and the incidences of Guillain-Barre syndrome.

21 Dec 2021

Molecular mechanism of SARS-Cov-2-induced thrombosis

Researchers demonstrate that the exposure of platelets to the SARS-CoV-2 spike protein promotes their activation and adhesion.

21 Dec 2021

Booster doses offer broader protection in SARS-CoV-2 infected and vaccinated individuals

Researchers determined IgG titers of vaccinated healthcare workers 11 months following primary COVID-19 vaccination.

21 Dec 2021

Severe COVID-19 found to be associated with disrupted intestinal Peyer’s patches

A new study demonstrates significantly altered structure and cellularity of Peyer’s patches in deceased COVID-19 patients.

21 Dec 2021

Diagnostic assays that use the 2019-nCoV-N1 primer-probe are unlikely to be impacted by Omicron variant

A new study aimed to detect the genomic material of SARS-CoV-2 and its variants, such as the recently emerged variant of concern (VOC) Omicron.

21 Dec 2021

Medical News

Clinical trial results do not support the use of fish oil supplements to prevent depression

Alternative statistical method can make clinical trials more reliable and trustworthy

Simple, inexpensive method to predict the risk of functional disability in older people

National U.S trial confirms effectiveness of mRNA COVID-19 vaccines

Proportion of ‘frequent attenders’ has risen over the past two decades, study reveals

Doctors advised to prescribe fewer antidepressants and for shorter periods of time

Promising new drug target for TB identified

3D-printed tracheal replacement splint offers hope for treating rare developmental abnormality

Comparison of SARS-CoV-2 rapid antigen tests

Early administration of SARS-CoV-2 convalescent plasma reduces outpatient hospitalizations

Risk of exposure to SARS-CoV-2 by workplace and trade

FDA approval of long-acting injectable drug marks a vital expansion of HIV prevention options

How the SARS-CoV-2 Omicron variant spike protein is changing

Comparison of point-of-care SARS-CoV-2 diagnostic kits

What are the long-term effects of COVID-19 on mental health?

UK research investigates relationship between COVID-19 vaccination and Guillain-Barré syndrome

Molecular mechanism of SARS-Cov-2-induced thrombosis

Booster doses offer broader protection in SARS-CoV-2 infected and vaccinated individuals

Severe COVID-19 found to be associated with disrupted intestinal Peyer’s patches

Diagnostic assays that use the 2019-nCoV-N1 primer-probe are unlikely to be impacted by Omicron variant

Voltammetry and machine learning for real-time neurotransmitter detection

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

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