1. Jason Adamcewicz Jason Adamcewicz Canada says:

    My understanding of the article is that the vaccine produces stronger/enhanced immune response to fungi, particularly candida albicans. Regarding other viruses, bacteria and fungi, it states that inflammatory cytokine production was "altered." The word "reduced" was used but it was to describe anti-inflammatory response to fungi, ie. increased inflammatory response which is another way of saying stronger immune response.

    I believe Indians with those fungal infections were naturally infected, not vaccinated, but the connection to what this article suggests has me concerned, as vaccination is meant to mimic infection in some ways. As someone who's suffered with chronic sinusitis of unknown cause (never been swabbed for fungal or bacterial cultures) for a long time, and having just received first Moderna dose, I am quite concerned.

    • Rick Boden Rick Boden Canada says:

      I'm responding to your post because I also have chronic sinusitis and suffered badly this winter to the extent it affected my sleep.  Nothing scientific about this but shortly after receiving the Pfizer shot, the symptoms almost completely disappeared.  Could be the changing season, who knows.

    • Guy Agin Guy Agin Canada says:

      You misunderstood the text. "In addition, the production of the anti-inflammatory cytokine interleukin-1Ra was reduced in response to Toll-like receptor 4 and C. albicans. This also suggests a shift towards increased inflammatory responses to fungi following vaccination, say the researchers."

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