1. ste 30 ste 30 United States says:

    While very exciting, the approach is hardly new. Several groups has already demonstrated that live-attenuated vaccine are significantly more effective than the subunit gD-2 approaches. For instance: Halford WP, Püschel R, Gershburg E, Wilber A, Gershburg S, et al. (2011) A Live-Attenuated HSV-2 ICP0− Virus Elicits 10 to 100 Times Greater Protection against Genital Herpes than a Glycoprotein D Subunit Vaccine. PLoS ONE 6(3): e17748. doi:10.1371/journal.pone.0017748

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