Posted in | Preclinical Imaging

How microCT Can Provide Insight into Dynamic Disease Processes

In this webinar, Professor Greetje Vande Velde will give an overview of her work, which involves lung and brain infections.  Professor Vande Velde will describe how high-field MRI and low dose microCT complement each other; where microCT gives high contrast in the lungs and MRI allows clear visualization of the brain.

The webinar will also introduce the use of the Skyscan 1278 microCT from Bruker, that was used in Professor Vande Velde’s experiments, as is a non-invasive imaging technique that can be used with the same animal multiple times - to not only create high quality images, but to also minimize the number of animals used in the trials.


Greetje Vande Velde

Greetje Vande Velde
Assistant Professor, KU Leuven

Greetje Vande Velde is an Assistant Professor in Imaging and Pathology at The KU Leuven (University of Leuven). Since completing her Ph.D. at KU Leuven, Greetje has held multiple research positions within and outside the university, and has published over 60 journal papers focused around imaging lung diseases and infections.

What to Expect?

This webinar will look at how non-invasive imaging can yield much better results at the preclinical stage and how the ethics of preclinical research can also be improved. Expect to see how the Skyscan 1278 microCT in combination with a BioSpec 9.4 T MRI can be used to improve the data generated from animals, regardless of the species or disease type. Viewers should also expect to see the many benefits this technique offers, as well as the types of disease that it is useful for.

Key Topics

Introduction to Micro CT


  • Data Processing (better and more relevant data)
  • Higher Image Quality
  • Ability to Image an animal multiple times
  • High spatial & temporal resolution
  • Low radiation dosage
  • Improved preclinical workflow

Combining CT with MRI


  • Lung disease
  • Cardiac disease
  • Metabolic diseases
  • Cancerous tumors
  • Brain imaging
  • Animal disease model phenotyping

Improving Ethics

  • Reducing the number of (transgenic) animals used in preclinical research/studies
  • Non-invasive

Who Should Attend?

The webinar is primarily aimed at those who work with animals, in particular transgenic animals, and are looking to refine and reduce, or improve their workflow. Additionally, people who are involved in lung, cardiac and neuroscience research would find this webinar useful.

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