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Acute stress modifies DNA methylation and activity of certain genes

Acute stress alters the methylation of the DNA and thus the activity of certain genes. This is reported by researchers at the Ruhr-Universität Bochum together with colleagues from Basel, Trier and London for the first time in the journal Translational Psychiatry. "The results provide evidence how stress could be related to a higher risk of mental or physical illness", says Prof. Dr. Gunther Meinlschmidt from the Clinic of Psychosomatic Medicine and Psychotherapy at the LWL University Hospital of the RUB.

16 Aug 2012

Cleveland Eye Clinic surgeons perform Corneal Cross-Linking procedure

For years, patients with an eye disease called keratoconus have had little to no hope of continuing to see well without glasses or contacts, and a portion of them had a high risk corneal transplant in their future. Keratoconus is an eye disease that causes the cornea (the clear covering on the eye) to become thin and steep over time. Patients with keratoconus can wear special contact lenses or in some cases glasses. Many of them lose the ability to see well even with corrective eye wear.

18 May 2012

Avedro, ACOS commence accelerated corneal cross-linking Phase 3 study

ACOS and Avedro, Inc. jointly announced today the initiation of a Phase 3, multi-center, randomized, controlled evaluation to study accelerated corneal collagen cross-linking in eyes with keratoconus or corneal ectasia after refractive surgery.

3 Apr 2012

Combination of everolimus and exemestane reduces spread of cancer in the bone

Results from a phase III clinical trial evaluating a new treatment for breast cancer in post-menopausal women show that the combination of two cancer drugs, everolimus and exemestane, significantly improves bone strength and reduces the chances of cancer spreading (metastasising) in the bone.

23 Mar 2012

Researchers describe preparation of chitosan nanoparticles

Nanoparticles containing chitosan have been shown to have effective antimicrobial activity against Staphylococcus saprophyticus and Escherichia coli. The materials could be used as a protective wound-healing material to avoid opportunistic infection as well as working to facilitate wound healing.

17 Mar 2012

Avedro submits VibeX/KXL System NDA with FDA to treat keratoconus, corneal ectasia

Avedro, Inc. announced today that the Company submitted a New Drug Application (NDA) to the United States Food and Drug Administration (FDA) for its VibeX (riboflavin ophthalmic solution) /KXL System for the treatment of keratoconus and corneal ectasia following refractive surgery.

9 Mar 2012

Neomend receives PMA from FDA for Progel Extended Applicator Spray Tip

Neomend, Inc., a leading innovator in sealant and adhesion-prevention products for the surgical marketplace, said it has received premarket approval from the U.S. Food and Drug Administration for use of the company's new Progel Extended Applicator Spray Tip.

9 Jan 2012

Avedro's Lasik Xtra procedure receives CE Approval

Avedro, Inc. announced today that the Company's proprietary Lasik Xtra procedure has received CE Approval. Lasik Xtra is a two minute procedure used in conjunction with standard Lasik to restore the biomechanical integrity and strength to the cornea after a Lasik procedure.

4 Jan 2012

Collagen crosslinking for keratoconus may receive FDA approval in 2012

Patients in the United States who have the cornea-damaging disease keratoconus may soon be able to benefit from a new treatment that is already proving effective in Europe and other parts of the world.

24 Oct 2011

UB scientists discover promising new drug target for Alzheimer's

A tiny piece of a critical receptor that fuels the brain and without which sentient beings cannot live has been discovered by University at Buffalo scientists as a promising new drug target for Alzheimer's and other neurodegenerative diseases.

12 Oct 2011

Researchers combine 3-D printing technology and multiphoton polymerization to develop artificial blood vessels

Researchers have been working at growing tissue and organs in the laboratory for a long time. These days, tissue engineering enables us to build up artificial tissue, although science still hasn't been successful with larger organs. Now, researchers at Fraunhofer are applying new techniques and materials to come up with artificial blood vessels in their BioRap project that will be able to supply artificial tissue and maybe even complex organs in future.

14 Sep 2011

Avedro acquires proprietary and patent pending transepithelial ParaCel riboflavin formulation

Avedro, Inc announced today that it has acquired all the intellectual property rights to produce, market, and distribute a breakthrough transepithelial riboflavin formulation based on the research of Roberto Pinelli, MD at the Istituto Laser Microchirurgia Oculare (ILMO) in Brescia, Italy.

14 Sep 2011

FDA grants orphan drug designation for Avedro's VibeX to treat Keratoconus

Avedro, Inc. announced today that the U.S. Food and Drug Administration (FDA) has granted orphan drug designation to the Company's VibeX for use with its KXL System (UVA irradiation) for Corneal Cross-linking to treat Keratoconus.

12 Sep 2011

Developing technologies to improve treatment of craniosynostosis in babies

Engineers and surgeons are working together to improve the treatment of babies born with craniosynostosis, a condition that causes the bone plates in the skull to fuse too soon. Treating this condition typically requires surgery after birth to remove portions of the fused skull bones, and in some cases the bones grow together again too quickly -- requiring additional surgeries.

8 Sep 2011

Patient recruitment complete in Kuros' KUR-023 dural sealant European clinical trial

Kuros Biosurgery AG, a biotechnology company focused on the development of novel biomaterials and bioactive-biomaterial combination products for trauma, wound and spinal indications, announced today that it has completed patient recruitment in a clinical trial investigating the safety and efficacy of KUR-023, its novel dural sealant product candidate.

17 Aug 2011

Insight into how molecular motor proteins save energy

The transport system inside living cells is a well-oiled machine with tiny protein motors hauling chromosomes, neurotransmitters and other vital cargo around the cell. These molecular motors are responsible for a variety of critical transport jobs, but they are not always on the go. They can put themselves into "energy save mode" to conserve cellular fuel and, as a consequence, control what gets moved around the cell, and when.

12 Aug 2011

New liquid material shows promise for people with facial deformities

Biomedical engineers at Johns Hopkins have developed a new liquid material that in early experiments in rats and humans shows promise in restoring damaged soft tissue relatively safely and durably.

2 Aug 2011

Shinagawa LASIK Center expands commercial relationship with Avedro

Avedro, Inc announced today that Shinagawa LASIK Centers has made a significant investment in expanding its use of Avedro products.

20 Jul 2011

Hydrogel capsule could simultaneously deliver different types of drugs

Researchers at the Georgia Institute of Technology have designed a multiple-compartment gel capsule that could be used to simultaneously deliver drugs of different types. The researchers used a simple "one-pot" method to prepare the hydrogel capsules, which measure less than one micron.

7 Jul 2011

Avedro receives Gold MDEA award for Vedera System

Avedro, Inc. announced today that the Vedera System for performing Keraflex has received the prestigious Gold level 2011 Medical Design Excellence Award.

22 Jun 2011