Mania News and Research

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Antidepressant risk in bipolar patients limited to monotherapy use

Antidepressants may cause problems in patients with bipolar disorder only when they are used in isolation, research suggests.

26 Jun 2014

DBS improves motor and non motor symptoms of patients with early Parkinson's disease

Deep brain stimulation (DBS) has become a well-recognized non-pharmacologic treatment that improves motor symptoms of patients with early and advanced Parkinson's disease.

26 Jun 2014

Depression 5 times common in people with bipolar disorder who have low levels of cortisol

Depression is almost twice as common, and poor quality of life almost five times as common, in people with bipolar disorder who have elevated or low levels of the stress hormone cortisol in the blood.

19 Jun 2014

Johns Hopkins to host 5th annual Graphic Medicine Conference

The Johns Hopkins University School of Medicine’s Department of Art as Applied to Medicine is hosting the fifth annual Graphic Medicine Conference, to take place June 26 to June 28 in the Preclinical Teaching Building on the Johns Hopkins medical campus.

17 Jun 2014

Predictive factors ‘raise suspicion’ for emergence of bipolar disorder

Researchers have identified seven factors that predict which patients initially diagnosed with depression will later meet the diagnostic criteria for bipolar disorder.

5 Jun 2014

Sudden loss of loved one can trigger psychiatric disorders in people with no history of mental illness

The sudden loss of a loved one can trigger a variety of psychiatric disorders in people with no history of mental illness, according to researchers at Columbia University's Mailman School of Public Health and colleagues at Columbia's School of Social Work and Harvard Medical School.

30 May 2014

Bipolar remission influenced by anxiety and OCD

Anxiety disorders and obsessive compulsive disorder may reduce the likelihood of achieving remission for patients with bipolar disorder, study findings indicate.

29 May 2014

Unexpected death may trigger mania in loved ones

The unexpected loss of a loved one can trigger a range of psychiatric disorders, including mania, in patients with no history of mental illness, a study shows.

23 May 2014

Depression does not impact on cognition in early bipolar disorder

Depressive episodes have no additional impact on cognition in patients early in the course of bipolar disorder, research suggests.

21 May 2014

Bipolar at-risk criteria identify ‘relevant clinical minority’

A set of ultra-high-risk criteria for bipolar disorder identifies a group of help-seeking patients with a high rate of new-onset mania or hypomania over the following year, say researchers.

19 May 2014

Age and onset age may influence bipolar treatment response

Some differences in treatment response emerge when patients with bipolar disorder are grouped according to their age and their age at bipolar onset, say researchers.

14 May 2014

Life events link to mania bolstered

Study findings support a role for childhood and adulthood stressors in the risk of both new-onset and recurrent mania.

8 May 2014

Smartphone app shows promise for detecting early signs of mood changes in people with bipolar disorder

A smartphone app that monitors subtle qualities of a person's voice during everyday phone conversations shows promise for detecting early signs of mood changes in people with bipolar disorder, a University of Michigan team reports.

8 May 2014

Migraine a depressing issue in bipolar disorder

Patients with bipolar disorder have a markedly increased prevalence of migraine, report researchers.

1 May 2014

Forest Laboratories, Richter report positive results from cariprazine Phase IIb trial for bipolar depression

Forest Laboratories, Inc. and Gedeon Richter Plc. today announced positive topline results from a Phase IIb trial evaluating the efficacy and safety of the investigational antipsychotic cariprazine in patients with bipolar depression.

31 Mar 2014

EEG findings specific to mood state in bipolar disorder

The electrical activity of the brain differs in patients with bipolar disorder according to whether they are experiencing a manic or depressed phase, research shows.

27 Mar 2014

Bidirectional link between life events and mood episodes

The link between life events and mood episodes in patients with bipolar disorder is bidirectional, with positive and negative life events having different effects, report researchers.

27 Mar 2014

Six dimensions explain mania symptom variability

Researchers have identified a six-factor latent structure that they say best describes the symptomatology of hospitalized patients with bipolar mania.

21 Mar 2014

Distinct motor activity patterns for bipolar depression and mania

Acutely ill patients with bipolar disorder show distinct differences in motor activity regulation during episodes of mania and depression, research indicates.

13 Mar 2014

BDNF abnormalities may predict bipolar disorder

Patients with bipolar disorder show abnormalities in the conversion of pro-brain derived neurotrophic factor to the mature form, which may be used to aid diagnosis of the condition.

28 Feb 2014