Muscle Wasting News and Research

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SLU scientists provide promising approach in designing new drugs for DMD

In a paper published in the Nature journal Scientific Reports, Saint Louis University researchers report that a new drug reduces fibrosis (scarring) and prevents loss of muscle function in an animal model of Duchenne muscular dystrophy (DMD), providing a promising approach in designing new medications for those suffering from DMD.

8 Dec 2017

Regular exercise may protect smokers from muscle loss and inflammation

Regular exercise may protect smokers from some of the negative effects associated with smoking, such as muscle loss and inflammation, according to a new study.

28 Nov 2017

New review addresses aspects of nutrition in liver transplant candidates with cirrhosis

Poor nutrition is common in patients with liver failure, or cirrhosis, and it can lead to muscle wasting, weakness, fatigue, and worse outcomes before and after patients undergo liver transplantation.

26 Oct 2017

CRISPR-Gold corrects gene mutations in mice with Duchenne muscular dystrophy

Scientists at the University of California, Berkeley, have engineered a new way to deliver CRISPR-Cas9 gene-editing technology inside cells and have demonstrated in mice that the technology can repair the mutation that causes Duchenne muscular dystrophy, a severe muscle-wasting disease.

4 Oct 2017

Cellular antennae play key role in muscle-to-fat transformation

Like it or not, as we age, our muscle cells are slowly exchanged, one by one, for fat cells. This process quickens when we injure a muscle, and an extreme form of this process is also seen in muscle-wasting diseases such as Duchenne muscular dystrophy (DMD).

13 Jul 2017

New approach could potentially prevent muscle wasting in muscular dystrophy and cancer

Monash University's Biomedicine Discovery Institute researchers have collaboratively developed a therapeutic approach that dramatically promotes the growth of muscle mass, which could potentially prevent muscle wasting in diseases including muscular dystrophy and cancer.

14 Jun 2017

Researchers discover connection between processes that keep the heart from repairing itself

Heart muscle is one of the least renewable tissues in the body, which is one of the reasons that heart disease is the leading cause of death for both men and women in the United States, according to the Centers for Disease Control and Prevention.

5 Jun 2017

Weekly doses of steroids help hasten recovery in muscle injuries

Weekly doses of glucocorticoid steroids, such as prednisone, help speed recovery in muscle injuries, reports a new Northwestern Medicine study. The weekly steroids also repaired muscles damaged by muscular dystrophy.

17 May 2017

Study unravels new clues to cause and treatment of spinal muscular atrophy

Spinal muscular atrophy, a neurodegenerative disease that causes progressive muscle wasting and paralysis, may be partly due to abnormalities in the synapses that connect sensory neurons and motor neurons, according to researchers at Columbia University Medical Center.

16 May 2017

Research sheds new light on the body's response to high salt intake

When you eat salty food, you get thirsty and drink water. Right? Maybe in the short-term, but within 24 hours, you actually get less thirsty because your body starts to conserve and produce more water.

17 Apr 2017

Research findings suggest potential strategies to combat IBMPFD and other degenerative diseases

UCLA researchers have discovered the molecular basis of, and identified potential treatment for, an incurable disease known as inclusion body myopathy, Paget disease with frontotemporal dementia, or IBMPFD.

21 Mar 2017

Gene therapy treats myotubular myopathy in dogs

The rare disorder, called myotubular myopathy, or MTM, affects only males. It causes fatal muscle wasting. Both dogs and boys with the disease typically succumb in early life due to breathing difficulties.

16 Feb 2017

Duke Health researchers identify potential new drug target for Huntington's disease

The loss of motor function and mental acuity associated with Huntington's disease might be treatable by restoring a cellular quality control process, which Duke Health researchers have identified as a key factor in the degenerative illness.

13 Feb 2017

Study discovers new form of congenital muscular dystrophy caused by faulty INPP5K gene

A new form of congenital muscular dystrophy has been discovered which is caused by mutations in a previously un-linked gene.

9 Feb 2017

FDA approves first drug to treat children and adults with spinal muscular atrophy

The U.S. Food and Drug Administration today approved Spinraza (nusinersen), the first drug approved to treat children and adults with spinal muscular atrophy (SMA), a rare and often fatal genetic disease affecting muscle strength and movement.

23 Dec 2016

TSRI scientists develop new methods to design precision medicines against disease-causing RNAs

Scientists on the Florida campus of The Scripps Research Institute have developed broad methods to design precision medicines against currently incurable diseases caused by RNA.

20 Dec 2016

Biologic drugs may help prevent progressive bone loss in patients with RA

A new review by the International Osteoporosis Foundation Chronic Inflammation and Bone Structure Working Group concludes that early and aggressive treatment of Rheumatoid Arthritis (RA) with biologic drugs, specifically biological disease-modifying anti-rheumatic drugs (DMARDs), may be most effective in halting progressive bone loss in patients with RA.

7 Nov 2016

Muscle Wasting News and Research

SLU scientists provide promising approach in designing new drugs for DMD

Regular exercise may protect smokers from muscle loss and inflammation

New review addresses aspects of nutrition in liver transplant candidates with cirrhosis

CRISPR-Gold corrects gene mutations in mice with Duchenne muscular dystrophy

Cellular antennae play key role in muscle-to-fat transformation

New approach could potentially prevent muscle wasting in muscular dystrophy and cancer

Researchers discover connection between processes that keep the heart from repairing itself

Weekly doses of steroids help hasten recovery in muscle injuries

Study unravels new clues to cause and treatment of spinal muscular atrophy

Research sheds new light on the body's response to high salt intake

Research findings suggest potential strategies to combat IBMPFD and other degenerative diseases

Gene therapy treats myotubular myopathy in dogs

Duke Health researchers identify potential new drug target for Huntington's disease

Study discovers new form of congenital muscular dystrophy caused by faulty INPP5K gene

FDA approves first drug to treat children and adults with spinal muscular atrophy

TSRI scientists develop new methods to design precision medicines against disease-causing RNAs

Biologic drugs may help prevent progressive bone loss in patients with RA

New, practical tool may help doctors to easily diagnose cachexia in cancer patients

Climbing Mount Kilimanjaro to research oxygen deprivation

Scientists find new target that may lead to future treatments for Kennedy's disease

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