Opioid Drug News and Research

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Watson Pharmaceuticals receives FDA approval for generic Duragesic

Watson Pharmaceuticals, Inc. announced today that it has received final approval from the United States (U.S.) Food and Drug Administration (FDA) on its Abbreviated New Drug Application (ANDA) for fentanyl transdermal system in the 25, 50, 75 & 100 mcg/hour strengths.

21 Aug 2007

Breakthrough pain medication

Cancer patients frequently experience two types of pain: persistent and breakthrough.

17 Aug 2007

Cannabis mouth spray eases pain of cancer patients

Canadian health authorities have given approval for a new cannabis-based painkiller for use with cancer patients.

8 Aug 2007

Gastroenterologist-directed sedation safe and effective for endoscopic procedures

The use of an evidence-based sedation protocol for endoscopic procedures improves the quality of practice and reduces the incidence of sedation-related adverse events, according to an AGA Institute Review of Endoscopic Sedation published in the August issue of Gastroenterology , the official journal of the American Gastroenterological Association (AGA) Institute.

3 Aug 2007

National study to treat addiction to prescription pain medications

Researchers funded by the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health, launched the first large-scale national study evaluating a treatment for addiction to prescription opioid analgesics (i.e., painkillers) such as Vicodin and OxyContin.

10 Jul 2007

Abiraterone reduces levels of prostate specific antigen

For prostate cancer patients whose tumors have continued to grow despite medical or surgical castration, a new drug candidate that inhibits production of male hormones anywhere in the body is showing promise in early trials.

9 Jul 2007

Targeted nalmefene with simple medical management in the treatment of heavy drinkers

Problem drinkers who took a craving-curbing drug whenever they felt the desire to imbibe reported fewer heavy drinking days each month than drinkers who took a look-alike placebo pill, but both groups reported marked reductions in heavy drinking days.

4 Jul 2007

Pain management is a fundamental human right

A growing international consensus urges change in several areas - including increased availability of controlled medications such as opioids - toward the goal of recognizing effective treatment for pain as a fundamental human right, according to a special article in the July issue of Anesthesia & Analgesia, the official publication of the International Anesthesia Research Society and published by Lippincott Williams & Wilkins.

27 Jun 2007

First comprehensive description of sleep and wake patterns of cancer patients using continuous polysomnography

Patients with advanced-stage cancer experience very poor sleep quality and often have troubling staying awake, says Emory University researcher Kathy Parker, PhD, RN.

14 Jun 2007

AMPAKINE drugs may provide protection from drug-induced respiratory depression

Drug-induced respiratory depression is a life-threatening condition caused by analgesic, hypnotic, and anesthesia medications.

5 Jun 2007

JRRD releases issue on pain

Effects of depression and pain severity on satisfaction in medical outpatients: Analysis of the Medical Outcomes Study, pg. 143 Patient satisfaction is a critical measure of healthcare quality.

1 Jun 2007

New gene therapy can nearly eliminate arthritis pain

Early-stage research has found that a new gene therapy can nearly eliminate arthritis pain, and significantly reduce long-term damage to the affected joints, according to a study published today in the journal Arthritis and Rheumatism.

28 May 2007

Caring for the sick now a public health priority for developing countries

Palliative care is commonly used in developed countries to improve the quality of life of patients with life-threatening illnesses, through strategies aimed mainly at pain relief.

10 May 2007

BEMA Fentanyl demonstrates substantial transmucosal delivery

BioDelivery Sciences International, Inc. (Nasdaq:BDSI) announced the results of a 12 subject, crossover study comparing the absorption of fentanyl from both single and multiple BEMA? Fentanyl discs, as well as oral and intravenous doses of fentanyl.

8 May 2007

Drug abuse in the U.S. not confined to minority groups

Researchers in the U.S. say more than 10 percent of American adults at some point in their lives, abuse or become addicted to drugs.

8 May 2007

Research paves the way for new therapies designed to manage heart disease in older population

Ischaemic heart disease, characterised by reduced blood flow to the heart, is Australia's and the world's leading cause of death.

4 May 2007

Food-associated cues linked to obesity

A unique pattern of gene expression observed in rats may be linked to a conditioned desire for food and excessive food intake, an article published in BMC Biology suggests.

27 Apr 2007

New theory of addiction as a disease of learning and memory

Morphine, as little as a single dose, blocks the brain's ability to strengthen connections at inhibitory synapses, according to new Brown University research published in Nature.

26 Apr 2007

Neuromed licenses chronic pain product from ALZA Corporation

Neuromed Pharmaceuticals has announced that it has licensed from ALZA Corporation the exclusive U.S. rights to develop and commercialize OROS(R) Hydromorphone, an extended release formulation of a potent opioid analgesic in Phase 3 clinical development.

25 Apr 2007

FDA approves Alpharma's KADIAN 10mg strength capsule

Alpharma Inc. has announced that it has been notified by the United States Food and Drug Administration(FDA) that its pending application for KADIAN 10mg strength capsule has received approval.

24 Apr 2007