Bone Marrow News and Research

RSS

Bone Marrow is the soft, sponge-like tissue in the center of most bones. It produces white blood cells, red blood cells, and platelets.

FDA approves drug to treat patients with newly diagnosed CD33-positive AML

The U.S. Food and Drug Administration today approved Mylotarg (gemtuzumab ozogamicin) for the treatment of adults with newly diagnosed acute myeloid leukemia whose tumors express the CD33 antigen (CD33-positive AML).

1 Sep 2017

Spot Leukaemia campaign launched to reduce delays in diagnosis

A UK leukemia charity, Leukaemia CARE, has launched the Spot Leukaemia campaign to raise awareness of the signs and symptoms of leukemia after a survey revealed that leukemia diagnoses are commonly delayed due to poor understanding.

1 Sep 2017

Study explores periodontal status of patients with Chédiak-Higashi syndrome

The International and American Associations for Dental Research have published an article titled "Periodontitis in Chédiak-Higashi Syndrome: An Altered Immunoinflammatory Response" in the JDR Clinical & Translational Research.

31 Aug 2017

UChicago Medicine working with Novartis to offer breakthrough gene therapy for pediatric ALL patients

The University of Chicago Medicine is one of a limited number of U.S. sites working to offer a breakthrough gene therapy for pediatric acute lymphoblastic leukemia (ALL), which was just approved by the U.S. Food and Drug Administration.

31 Aug 2017

FDA makes the first gene therapy Kymriah available for treatment of pediatric ALL

The U.S. Food and Drug Administration (FDA) has issued a press release making the first even gene therapy available for treatment of children with a form of acute lymphoblastic leukemia (ALL).

30 Aug 2017

$Novartis gets FDA approval for novel immunocellular therapy to treat relapsed or refractory B-cell ALL$

Novartis gets FDA approval for novel immunocellular therapy to treat relapsed or refractory B-cell ALL

Novartis announced today that the US Food and Drug Administration has approved Kymriah (tisagenlecleucel) suspension for intravenous infusion, formerly CTL019, the first chimeric antigen receptor T cell (CAR-T) therapy, for the treatment of patients up to 25 years of age with B-cell precursor acute lymphoblastic leukemia (ALL) that is refractory or in second or later relapse.

30 Aug 2017

Pioneering cancer gene therapy gets green light — and $475,000 price tag

The country's first approved gene therapy — approved Wednesday to fight leukemia that resists standard therapies — will cost $475,000 for a one-time treatment, its manufacturer announced.

30 Aug 2017

New biomedical tool using nanoparticles could improve therapies for many diseases

A new biomedical tool using nanoparticles that deliver transient gene changes to targeted cells could make therapies for a variety of diseases - including cancer, diabetes and HIV - faster and cheaper to develop, and more customizable.

30 Aug 2017

FDA approves first cell-based gene therapy for use in the United States

The U.S. Food and Drug Administration issued a historic action today making the first gene therapy available in the United States, ushering in a new approach to the treatment of cancer and other serious and life-threatening diseases.

30 Aug 2017

FDA grants accelerated approval to new treatment for children with Chagas disease

The U.S. Food and Drug Administration today granted accelerated approval to benznidazole for use in children ages 2 to 12 years old with Chagas disease. It is the first treatment approved in the United States for the treatment of Chagas disease.

29 Aug 2017

Extensive analysis reveals immune system dynamics after stem cell transplantation in leukemia patients

By combining new system-biological analyses and advanced data analysis, researchers at Karolinska Institutet have been able to monitor the maturation process of the immune system of leukemia patients who have undergone stem cell transplantation.

29 Aug 2017

Targeting bone marrow protein could be effective way to improve stem cell transplants

Bone marrow contains hematopoetic stem cells, the precursors to every blood cell type. These cells spring into action following bone marrow transplants, bone marrow injury and during systemic infection, creating new blood cells, including immune cells, in a process known as hematopoiesis.

28 Aug 2017

UC San Diego researchers receive $18.2 million grant for B cell cancer clinical trial

The Independent Citizens Oversight Committee of the California Institute for Regenerative Medicine today unanimously approved an $18.29 million grant to University of California San Diego School of Medicine researchers to fund a phase Ib/IIa clinical trial of a novel combination drug therapy for B-cell cancers.

26 Aug 2017

First FDA-approved stem cell trial for shoulder injuries reaches full enrollment

The trial is the first in the United States to offer an FDA-approved adipose-derived stem cell trial for shoulder injuries.

24 Aug 2017

Bacterial infections may trigger dysregulation of blood formation

It has been thought that only immune cells would act as the line of defense during bacterial infection. However, recent research has revealed that hematopoietic stem cells, cells that create all other blood cells throughout an individual's lifetime, are also able to respond to the infection.

24 Aug 2017

Researchers identify important adenovirus receptor in macrophages of mice

Adenoviral infections have a mild disease progression in healthy people, but it can be dangerous for immunocompromised people.

24 Aug 2017

Our body contains more diverse microbes than previously known, new survey suggests

A new survey of DNA fragments circulating in human blood suggests our bodies contain vastly more diverse microbes than anyone previously understood.

23 Aug 2017

‘Breakthrough’ leukemia drug also portends ‘quantum leap’ in cost

When doctors talk about a new leukemia drug from Novartis, they ooze enthusiasm, using words like "breakthrough," "revolutionary" and "a watershed moment."

23 Aug 2017

FDA approves Besponsa – Pfizer’s new drug for rare form of acute lymphoblastic leukemia

The U.S. Food and Drug Administration (FDA) today approved Besponsa (inotuzumab ozogamicin) in the treatment of adults with relapsed or refractory B-cell precursor acute lymphoblastic leukemia (ALL) - a rare form of ALL.

17 Aug 2017

Researchers get closer to creating new blood test that can identify breast cancer brain metastasis

Houston Methodist cancer researchers are now closer to creating a blood test that can identify breast cancer patients who are at increased risk for developing brain metastasis, and also monitor disease progression and response to therapy in real time.

17 Aug 2017

Bone Marrow News and Research

Further Reading

FDA approves drug to treat patients with newly diagnosed CD33-positive AML

Spot Leukaemia campaign launched to reduce delays in diagnosis

Study explores periodontal status of patients with Chédiak-Higashi syndrome

UChicago Medicine working with Novartis to offer breakthrough gene therapy for pediatric ALL patients

FDA makes the first gene therapy Kymriah available for treatment of pediatric ALL

Novartis gets FDA approval for novel immunocellular therapy to treat relapsed or refractory B-cell ALL

Pioneering cancer gene therapy gets green light — and $475,000 price tag

New biomedical tool using nanoparticles could improve therapies for many diseases

FDA approves first cell-based gene therapy for use in the United States

FDA grants accelerated approval to new treatment for children with Chagas disease

Extensive analysis reveals immune system dynamics after stem cell transplantation in leukemia patients

Targeting bone marrow protein could be effective way to improve stem cell transplants

UC San Diego researchers receive $18.2 million grant for B cell cancer clinical trial

First FDA-approved stem cell trial for shoulder injuries reaches full enrollment

Bacterial infections may trigger dysregulation of blood formation

Researchers identify important adenovirus receptor in macrophages of mice

Our body contains more diverse microbes than previously known, new survey suggests

‘Breakthrough’ leukemia drug also portends ‘quantum leap’ in cost

FDA approves Besponsa – Pfizer’s new drug for rare form of acute lymphoblastic leukemia

Researchers get closer to creating new blood test that can identify breast cancer brain metastasis

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News