Metastasis News and Research

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Metastasis is the spread of cancer from one part of the body to another. A tumor formed by cells that have spread is called a “metastatic tumor” or a “metastasis.” The metastatic tumor contains cells that are like those in the original (primary) tumor. The plural form of metastasis is metastases

Study shows involvement of lipid metabolism in tumour metastasis

A study headed by Salvador Aznar Benitah, ICREA researcher at the Institute for Research in Biomedicine, and published today in Nature identifies metastasis-initiating cells through a specific marker, namely the protein CD36.

7 Dec 2016

Study highlights requirement of protein in initiation of apoptosis in uveal melanoma

New research from the University of Liverpool has identified the role of a specific protein in the human body that can help prevent the survival and spread of eye cancer, by initiating cancer 'cell-suicide'.

6 Dec 2016

Scientists identify potential dual-acting therapeutic strategy for aggressive form of breast cancer

A promising new combination therapy for a particularly aggressive form of breast cancer has been identified by Weizmann Institute scientists, as was recently reported in Cancer Research.

5 Dec 2016

ACS approves $1.7 million funding for new research grants to Yale University

The American Cancer Society, the largest non-government, not-for-profit funding source of cancer research in the United States, has approved funding for three new research grants totaling over $1.7 million to investigators at Yale University.

2 Dec 2016

Novel imaging agent can rapidly and accurately detect metastasis of prostate cancer

New research demonstrates that a novel imaging agent can quickly and accurately detect metastasis of prostate cancer, even in areas where detection has previously been difficult.

2 Dec 2016

Scientists identify cell-surface receptor for progranulin

Progranulin is produced and secreted by most cells in the body. From skin to immune cells, brain to bone marrow cells, progranulin plays a key role in maintaining normal cellular function.

30 Nov 2016

MGH researchers develop new methods for mapping and measuring solid stress in tumors

Massachusetts General Hospital investigators have developed new methods for mapping and measuring solid stress - the force exerted by solid and elastic components - within tumors, an accomplishment that may lead to improved understanding of those forces and their consequences and to novel treatment strategies.

29 Nov 2016

New ULB study shows how cancer cell of origin controls malignant transition

Researchers at the Université libre de Bruxelles, ULB define for the first time how the cancer cell of origin controls invasive and metastatic properties of tumor cells.

24 Nov 2016

Low-dose chemotherapy regimens may be more effective at treating certain breast and pancreatic cancer types

Conventional, high-dose chemotherapy treatments can cause the fibroblast cells surrounding tumors to secrete proteins that promote the tumors' recurrence in more aggressive forms, researchers at Taipei Medical University and the National Institute of Cancer Research in Taiwan and University of California, San Francisco, have discovered.

24 Nov 2016

NUS scientists find new mechanism to inhibit breast cancer metastasis

A team of researchers from the Cancer Science Institute of Singapore at the National University of Singapore has found that controlling the levels of the TIP60 protein, which is a tumour suppressor, could potentially prevent the spread of breast cancer cells.

23 Nov 2016

Research shows cellular component may play vital role in how lung cancer spreads

A cellular component known as the Golgi apparatus may play a role in how lung cancer metastasizes, according to researchers at The University of Texas MD Anderson Cancer Center whose findings were reported in the Nov. 21 online issue of the Journal of Clinical Investigation.

21 Nov 2016

Blocking key nutrient uptake may be effective way of treating triple negative breast cancer

Cancer rewires the metabolism of tumor cells, converting them into lean, mean, replicating machines.

21 Nov 2016

Study uncovers mechanism that causes chemo resistance of pancreatic cancer cells

A pioneering University of Liverpool research team have published a study that identifies the mechanism in the human body that causes resistance of pancreatic cancer cells to chemotherapy.

21 Nov 2016

Sleep apnea can make lung cancer more dangerous by increasing tumor growth

A team of researchers from the University of Chicago and the University of Barcelona has found that intermittent hypoxia, or an irregular lack of air experienced by people with sleep apnea, can increase tumor growth by promoting the release of circulating exosomes.

17 Nov 2016

BUSM researchers discover new pathway and protein involved in metastasis of breast cancer

Researchers have identified a new pathway and with it a protein, BRD4, necessary for breast cancer cells to spread.

15 Nov 2016

Researcher investigating drugs to prevent lung cancer from spreading

The American Cancer Society has reported that lung cancer, which kills more Americans than any other type of cancer, is expected result in an estimated 158,080 deaths in 2016.

11 Nov 2016

Researchers describe new method that can reveal distinct invasive properties of cancer cells

A research team at Georgetown Lombardi Comprehensive Cancer Center has described the steps, in both written and video format, that allow cancer investigators to track, in real time, cancer cell invasion and metastasis in transparent zebrafish embryos.

4 Nov 2016

Researchers identify marker of aggressive disease for papillary thyroid cancer

A new discovery from University of Alberta scientists represents an important milestone in the fight against thyroid cancer. In a study published in EBioMedicine and recently presented at the American Thyroid Association annual meeting, the team has identified a marker of aggressive disease for papillary thyroid cancer, which comprises about 90 per cent of all thyroid cancers.

3 Nov 2016

Research shows way to directly target genes within specific cell type

The cornerstone of genetics is the loss-of-function experiment. In short, this means that to figure out what exactly gene X is doing in a tissue of interest—be it developing brain cells or a pancreatic tumor—you somehow cut out, switch off or otherwise destroy gene X in that tissue and then watch what happens.

1 Nov 2016

Scientists discover how MEK inhibitor boosts antitumor activity and slows cancer progression

Understanding the effects of certain targeted therapies on antitumor immunity is necessary to design combined interventions for more effective cancer treatment.

1 Nov 2016

Metastasis News and Research

Further Reading

Study shows involvement of lipid metabolism in tumour metastasis

Study highlights requirement of protein in initiation of apoptosis in uveal melanoma

Scientists identify potential dual-acting therapeutic strategy for aggressive form of breast cancer

ACS approves $1.7 million funding for new research grants to Yale University

Novel imaging agent can rapidly and accurately detect metastasis of prostate cancer

Scientists identify cell-surface receptor for progranulin

MGH researchers develop new methods for mapping and measuring solid stress in tumors

New ULB study shows how cancer cell of origin controls malignant transition

Low-dose chemotherapy regimens may be more effective at treating certain breast and pancreatic cancer types

NUS scientists find new mechanism to inhibit breast cancer metastasis

Research shows cellular component may play vital role in how lung cancer spreads

Blocking key nutrient uptake may be effective way of treating triple negative breast cancer

Study uncovers mechanism that causes chemo resistance of pancreatic cancer cells

Sleep apnea can make lung cancer more dangerous by increasing tumor growth

BUSM researchers discover new pathway and protein involved in metastasis of breast cancer

Researcher investigating drugs to prevent lung cancer from spreading

Researchers describe new method that can reveal distinct invasive properties of cancer cells

Researchers identify marker of aggressive disease for papillary thyroid cancer

Research shows way to directly target genes within specific cell type

Scientists discover how MEK inhibitor boosts antitumor activity and slows cancer progression

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